Identification of Fungicidal 2,6-Disubstituted Quinolines with Activity against Candida Biofilms

por Delattin, Nicolas, Bardiot, Dorothée, Marchand, Arnaud, Chaltin, Patrick, De Brucker, Katrijn, Cammue, Bruno P. A., Thevissen, Karin
Publicado 2012

Differential antiviral activities of respiratory syncytial virus (RSV) inhibitors in human airway epithelium

por Mirabelli, Carmen, Jaspers, Martine, Boon, Mieke, Jorissen, Mark, Koukni, Mohamed, Bardiot, Dorothée, Chaltin, Patrick, Marchand, Arnaud, Neyts, Johan, Jochmans, Dirk
Publicado 2018

Dual inhibition of SARS-CoV-2 and human rhinovirus with protease inhibitors in clinical development

por Liu, Cheng, Boland, Sandro, Scholle, Michael D., Bardiot, Dorothee, Marchand, Arnaud, Chaltin, Patrick, Blatt, Lawrence M., Beigelman, Leonid, Symons, Julian A., Raboisson, Pierre, Gurard-Levin, Zachary A., Vandyck, Koen, Deval, Jerome
Publicado 2021

ALG-097111, a potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease inhibitor exhibits in vivo efficacy in a Syrian Hamster model

por Vandyck, Koen, Abdelnabi, Rana, Gupta, Kusum, Jochmans, Dirk, Jekle, Andreas, Deval, Jerome, Misner, Dinah, Bardiot, Dorothée, Foo, Caroline S., Liu, Cheng, Ren, Suping, Beigelman, Leonid, Blatt, Lawrence M., Boland, Sandro, Vangeel, Laura, Dejonghe, Steven, Chaltin, Patrick, Marchand, Arnaud, Serebryany, Vladimir, Stoycheva, Antitsa, Chanda, Sushmita, Symons, Julian A., Raboisson, Pierre, Neyts, Johan
Publicado 2021

The Substitutions L50F, E166A, and L167F in SARS-CoV-2 3CLpro Are Selected by a Protease Inhibitor In Vitro and Confer Resistance To Nirmatrelvir

por Jochmans, Dirk, Liu, Cheng, Donckers, Kim, Stoycheva, Antitsa, Boland, Sandro, Stevens, Sarah K., De Vita, Chloe, Vanmechelen, Bert, Maes, Piet, Trüeb, Bettina, Ebert, Nadine, Thiel, Volker, De Jonghe, Steven, Vangeel, Laura, Bardiot, Dorothée, Jekle, Andreas, Blatt, Lawrence M., Beigelman, Leonid, Symons, Julian A., Raboisson, Pierre, Chaltin, Patrick, Marchand, Arnaud, Neyts, Johan, Deval, Jerome, Vandyck, Koen
Publicado 2023

Synthesis, Structure–Activity Relationships, and Antiviral Profiling of 1-Heteroaryl-2-Alkoxyphenyl Analogs as Inhibitors of SARS-CoV-2 Replication

por Bardiot, Dorothée, Vangeel, Laura, Koukni, Mohamed, Arzel, Philippe, Zwaagstra, Marleen, Lyoo, Heyrhyoung, Wanningen, Patrick, Ahmad, Shamshad, Zhang, Linlin, Sun, Xinyuanyuan, Delpal, Adrien, Eydoux, Cecilia, Guillemot, Jean-Claude, Lescrinier, Eveline, Klaassen, Hugo, Leyssen, Pieter, Jochmans, Dirk, Castermans, Karolien, Hilgenfeld, Rolf, Robinson, Colin, Decroly, Etienne, Canard, Bruno, Snijder, Eric J., van Hemert, Martijn J., van Kuppeveld, Frank, Chaltin, Patrick, Neyts, Johan, De Jonghe, Steven, Marchand, Arnaud
Publicado 2022

Blocking NS3–NS4B interaction inhibits dengue virus in non-human primates

por Goethals, Olivia, Kaptein, Suzanne J. F., Kesteleyn, Bart, Bonfanti, Jean-François, Van Wesenbeeck, Liesbeth, Bardiot, Dorothée, Verschoor, Ernst J., Verstrepen, Babs E., Fagrouch, Zahra, Putnak, J. Robert, Kiemel, Dominik, Ackaert, Oliver, Straetemans, Roel, Lachau-Durand, Sophie, Geluykens, Peggy, Crabbe, Marjolein, Thys, Kim, Stoops, Bart, Lenz, Oliver, Tambuyzer, Lotke, De Meyer, Sandra, Dallmeier, Kai, McCracken, Michael K., Gromowski, Gregory D., Rutvisuttinunt, Wiriya, Jarman, Richard G., Karasavvas, Nicos, Touret, Franck, Querat, Gilles, de Lamballerie, Xavier, Chatel-Chaix, Laurent, Milligan, Gregg N., Beasley, David W. C., Bourne, Nigel, Barrett, Alan D. T., Marchand, Arnaud, Jonckers, Tim H. M., Raboisson, Pierre, Simmen, Kenny, Chaltin, Patrick, Bartenschlager, Ralf, Bogers, Willy M., Neyts, Johan, Van Loock, Marnix
Publicado 2023