Targeting Epigenetic Aberrations in Pancreatic Cancer, a New Path to Improve Patient Outcomes?

por Paradise, Brooke D., Barham, Whitney, Fernandez-Zapico, Martín E.
Publicado 2018

Thymoquinone enhances cisplatin-response through direct tumor effects in a syngeneic mouse model of ovarian cancer

por Wilson, Andrew J., Saskowski, Jeanette, Barham, Whitney, Yull, Fiona, Khabele, Dineo
Publicado 2015

Microenvironmental effects limit efficacy of thymoquinone treatment in a mouse model of ovarian cancer

por Wilson, Andrew J., Saskowski, Jeanette, Barham, Whitney, Khabele, Dineo, Yull, Fiona
Publicado 2015

Paradox-driven adventures in the development of cancer immunology and immunotherapy

por Barham, Whitney, Gicobi, Joanina K., Yan, Yiyi, Dronca, Roxana S., Dong, Haidong
Publicado 2019

Case Report: Simultaneous Hyperprogression and Fulminant Myocarditis in a Patient With Advanced Melanoma Following Treatment With Immune Checkpoint Inhibitor Therapy

por Barham, Whitney, Guo, Ruifeng, Park, Sean S., Herrmann, Joerg, Dong, Haidong, Yan, Yiyi
Publicado 2021

Manipulating the NF-κB pathway in macrophages using mannosylated, siRNA-delivering nanoparticles can induce immunostimulatory and tumor cytotoxic functions

por Ortega, Ryan A, Barham, Whitney, Sharman, Kavya, Tikhomirov, Oleg, Giorgio, Todd D, Yull, Fiona E
Publicado 2016

Inhibition of NF-kappaB activity in mammary epithelium increases tumor latency and decreases tumor burden

por Connelly, Linda, Barham, Whitney, Onishko, Halina M., Sherrill, Taylor, Chodosh, Lewis A., Blackwell, Timothy S., Yull, Fiona E.
Publicado 2010

Tracking NF-κB activity in tumor cells during ovarian cancer progression in a syngeneic mouse model

por Wilson, Andrew J, Barham, Whitney, Saskowski, Jeanette, Tikhomirov, Oleg, Chen, Lianyi, Lee, Hye-Jeong, Yull, Fiona, Khabele, Dineo
Publicado 2013

Aberrant activation of NF-κB signaling in mammary epithelium leads to abnormal growth and ductal carcinoma in situ

por Barham, Whitney, Chen, Lianyi, Tikhomirov, Oleg, Onishko, Halina, Gleaves, Linda, Stricker, Thomas P., Blackwell, Timothy S., Yull, Fiona E.
Publicado 2015

NF-kappaB activation within macrophages leads to an anti-tumor phenotype in a mammary tumor lung metastasis model

por Connelly, Linda, Barham, Whitney, Onishko, Halina M, Chen, Lianyi, Sherrill, Taylor P, Zabuawala, Tahera, Ostrowski, Michael C, Blackwell, Timothy S, Yull, Fiona E
Publicado 2011

A Novel Humanized PD-1/PD-L1 Mouse Model Permits Direct Comparison of Antitumor Immunity Generated by Food and Drug Administration–Approved PD-1 and PD-L1 Inhibitors

por Barham, Whitney, Hsu, Michelle, Liu, Xin, Harrington, Susan M., Hirdler, Jacob B., Gicobi, Joanina K., Zhu, Xingxing, Zeng, Hu, Pavelko, Kevin D., Yan, Yiyi, Mansfield, Aaron S., Dong, Haidong
Publicado 2023

Increased canonical NF-kappaB signaling specifically in macrophages is sufficient to limit tumor progression in syngeneic murine models of ovarian cancer

por Hoover, Alyssa A., Hufnagel, Demetra H., Harris, Whitney, Bullock, Kennady, Glass, Evan B., Liu, Esther, Barham, Whitney, Crispens, Marta A., Khabele, Dineo, Giorgio, Todd D., Wilson, Andrew J., Yull, Fiona E.
Publicado 2020

Immunity drives TET1 regulation in cancer through NF-κB

por Collignon, Evelyne, Canale, Annalisa, Al Wardi, Clémence, Bizet, Martin, Calonne, Emilie, Dedeurwaerder, Sarah, Garaud, Soizic, Naveaux, Céline, Barham, Whitney, Wilson, Andrew, Bouchat, Sophie, Hubert, Pascale, Van Lint, Carine, Yull, Fiona, Sotiriou, Christos, Willard-Gallo, Karen, Noel, Agnès, Fuks, François
Publicado 2018

Salvage therapy expands highly cytotoxic and metabolically fit resilient CD8(+) T cells via ME1 up-regulation

por Gicobi, Joanina K., Mao, Zhiming, DeFranco, Grace, Hirdler, Jacob B., Li, Ying, Vianzon, Vianca V., Dellacecca, Emilia R., Hsu, Michelle A., Barham, Whitney, Yan, Yiyi, Mansfield, Aaron S., Lin, Yi, Wu, Xiaosheng, Hitosugi, Taro, Owen, Dawn, Grams, Michael P., Orme, Jacob J., Lucien, Fabrice, Zeng, Hu, Park, Sean S., Dong, Haidong
Publicado 2023

NKG7 Is a T-cell–Intrinsic Therapeutic Target for Improving Antitumor Cytotoxicity and Cancer Immunotherapy

por Wen, Ti, Barham, Whitney, Li, Ying, Zhang, Henan, Gicobi, Joanina K., Hirdler, Jacob B., Liu, Xin, Ham, Hyoungjun, Peterson Martinez, Kodi E., Lucien, Fabrice, Lavoie, Roxane R., Li, Hu, Correia, Cristina, Monie, Dileep D., An, Zesheng, Harrington, Susan M., Wu, Xiaosheng, Guo, Ruifeng, Dronca, Roxana S., Mansfield, Aaron S., Yan, Yiyi, Markovic, Svetomir N., Park, Sean S., Sun, Jie, Qin, Hong, Liu, Minetta C., Vasmatzis, George, Billadeau, Daniel D., Dong, Haidong
Publicado 2022