Rationally Designed Anti-CRISPR Nucleic Acid Inhibitors of CRISPR-Cas9

por Barkau, Christopher L., O'Reilly, Daniel, Rohilla, Kushal J., Damha, Masad J., Gagnon, Keith T.
Publicado 2019

Binding to the conserved and stably folded guide RNA pseudoknot induces Cas12a conformational changes during ribonucleoprotein assembly

por Sudhakar, Sruthi, Barkau, Christopher L., Chilamkurthy, Ramadevi, Barber, Halle M., Pater, Adrian A., Moran, Sean D., Damha, Masad J., Pradeepkumar, P.I., Gagnon, Keith T.
Publicado 2023

Extensive CRISPR RNA modification reveals chemical compatibility and structure-activity relationships for Cas9 biochemical activity

por O’Reilly, Daniel, Kartje, Zachary J, Ageely, Eman A, Malek-Adamian, Elise, Habibian, Maryam, Schofield, Annabelle, Barkau, Christopher L, Rohilla, Kushal J, DeRossett, Lauren B, Weigle, Austin T, Damha, Masad J, Gagnon, Keith T
Publicado 2019

High throughput nanopore sequencing of SARS-CoV-2 viral genomes from patient samples

por Pater, Adrian A., Bosmeny, Michael S., White, Adam A., Sylvain, Rourke J., Eddington, Seth B., Parasrampuria, Mansi, Ovington, Katy N., Metz, Paige E., Yinusa, Abadat O., Barkau, Christopher L., Chilamkurthy, Ramadevi, Benzinger, Scott W., Hebert, Madison. M., Gagnon, Keith T.
Publicado 2021