Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2

por Barker, Harlan, Parkkila, Seppo
Publicado 2020

Molecular Mechanisms Associated with ROR1-Mediated Drug Resistance: Crosstalk with Hippo-YAP/TAZ and BMI-1 Pathways

por Karvonen, Hanna, Barker, Harlan, Kaleva, Laura, Niininen, Wilhelmiina, Ungureanu, Daniela
Publicado 2019

Bioinformatic analysis of beta carbonic anhydrase sequences from protozoans and metazoans

por Zolfaghari Emameh, Reza, Barker, Harlan, Tolvanen, Martti E E, Ortutay, Csaba, Parkkila, Seppo
Publicado 2014

A reverse vaccinology approach on transmembrane carbonic anhydrases from Plasmodium species as vaccine candidates for malaria prevention

por Zolfaghari Emameh, Reza, Barker, Harlan R., Turpeinen, Hannu, Parkkila, Seppo, Hytönen, Vesa P.
Publicado 2022

Beta carbonic anhydrases: novel targets for pesticides and anti-parasitic agents in agriculture and livestock husbandry

por Zolfaghari Emameh, Reza, Barker, Harlan, Hytönen, Vesa P, Tolvanen, Martti E E, Parkkila, Seppo
Publicado 2014

Ascaris lumbricoides β carbonic anhydrase: a potential target enzyme for treatment of ascariasis

por Zolfaghari Emameh, Reza, Kuuslahti, Marianne, Vullo, Daniela, Barker, Harlan R., Supuran, Claudiu T., Parkkila, Seppo
Publicado 2015

Horizontal transfer of β-carbonic anhydrase genes from prokaryotes to protozoans, insects, and nematodes

por Zolfaghari Emameh, Reza, Barker, Harlan R., Tolvanen, Martti E. E., Parkkila, Seppo, Hytönen, Vesa P.
Publicado 2016

Carbonic anhydrase related protein expression in astrocytomas and oligodendroglial tumors

por Karjalainen, Sini L., Haapasalo, Hannu K., Aspatwar, Ashok, Barker, Harlan, Parkkila, Seppo, Haapasalo, Joonas A.
Publicado 2018

Evaluating Targeted Therapies in Ovarian Cancer Metabolism: Novel Role for PCSK9 and Second Generation mTOR Inhibitors

por Jacome Sanz, Dafne, Raivola, Juuli, Karvonen, Hanna, Arjama, Mariliina, Barker, Harlan, Murumägi, Astrid, Ungureanu, Daniela
Publicado 2021

Chromatin accessibility is associated with CRISPR-Cas9 efficiency in the zebrafish (Danio rerio)

por Uusi-Mäkelä, Meri I. E., Barker, Harlan R., Bäuerlein, Carina A., Häkkinen, Tomi, Nykter, Matti, Rämet, Mika
Publicado 2018

Zebrafish as a Model Organism for the Development of Drugs for Skin Cancer

por Bootorabi, Fatemeh, Manouchehri, Hamed, Changizi, Reza, Barker, Harlan, Palazzo, Elisabetta, Saltari, Annalisa, Parikka, Mataleena, Pincelli, Carlo, Aspatwar, Ashok
Publicado 2017

β-CA-specific inhibitor dithiocarbamate Fc14–584B: a novel antimycobacterial agent with potential to treat drug-resistant tuberculosis

por Aspatwar, Ashok, Hammarén, Milka, Koskinen, Sanni, Luukinen, Bruno, Barker, Harlan, Carta, Fabrizio, Supuran, Claudiu T., Parikka, Mataleena, Parkkila, Seppo
Publicado 2017

Design, synthesis, in vitro inhibition and toxicological evaluation of human carbonic anhydrases I, II and IX inhibitors in 5-nitroimidazole series

por Aspatwar, Ashok, Parvathaneni, Nanda Kumar, Barker, Harlan, Anduran, Emilie, Supuran, Claudiu T., Dubois, Ludwig, Lambin, Philippe, Parkkila, Seppo, Winum, Jean-Yves
Publicado 2019

The production and biochemical characterization of α-carbonic anhydrase from Lactobacillus rhamnosus GG

por Urbański, Linda J., Bua, Silvia, Angeli, Andrea, Emameh, Reza Zolfaghari, Barker, Harlan R., Kuuslahti, Marianne, Hytönen, Vesa P., Parkkila, Seppo, Supuran, Claudiu T.
Publicado 2022

Cloning, purification, kinetic and anion inhibition studies of a recombinant β-carbonic anhydrase from the Atlantic salmon parasite platyhelminth Gyrodactylus salaris

por Aspatwar, Ashok, Barker, Harlan, Aisala, Heidi, Zueva, Ksenia, Kuuslahti, Marianne, Tolvanen, Martti, Primmer, Craig R., Lumme, Jaakko, Bonardi, Alessandro, Tripathi, Amit, Parkkila, Seppo, Supuran, Claudiu T.
Publicado 2022

Nitroimidazole-based inhibitors DTP338 and DTP348 are safe for zebrafish embryos and efficiently inhibit the activity of human CA IX in Xenopus oocytes

por Aspatwar, Ashok, Becker, Holger M., Parvathaneni, Nanda Kumar, Hammaren, Milka, Svorjova, Aleksandra, Barker, Harlan, Supuran, Claudiu T., Dubois, Ludwig, Lambin, Philippe, Parikka, Mataleena, Parkkila, Seppo, Winum, Jean-Yves
Publicado 2018

Role of carbonic anhydrases in skin wound healing

por Barker, Harlan, Aaltonen, Marleena, Pan, Peiwen, Vähätupa, Maria, Kaipiainen, Pirkka, May, Ulrike, Prince, Stuart, Uusitalo-Järvinen, Hannele, Waheed, Abdul, Pastoreková, Silvia, Sly, William S, Parkkila, Seppo, Järvinen, Tero AH
Publicado 2017

Glucocorticoids induce differentiation and chemoresistance in ovarian cancer by promoting ROR1-mediated stemness

por Karvonen, Hanna, Arjama, Mariliina, Kaleva, Laura, Niininen, Wilhelmiina, Barker, Harlan, Koivisto-Korander, Riitta, Tapper, Johanna, Pakarinen, Päivi, Lassus, Heini, Loukovaara, Mikko, Bützow, Ralf, Kallioniemi, Olli, Murumägi, Astrid, Ungureanu, Daniela
Publicado 2020

Inactivation of ca10a and ca10b Genes Leads to Abnormal Embryonic Development and Alters Movement Pattern in Zebrafish

por Aspatwar, Ashok, Tolvanen, Martti E. E., Ojanen, Markus J. T., Barker, Harlan R., Saralahti, Anni K., Bäuerlein, Carina A., Ortutay, Csaba, Pan, Peiwen, Kuuslahti, Marianne, Parikka, Mataleena, Rämet, Mika, Parkkila, Seppo
Publicado 2015

Identification and characterization of a novel zebrafish (Danio rerio) pentraxin–carbonic anhydrase

por Patrikainen, Maarit S., Tolvanen, Martti E.E., Aspatwar, Ashok, Barker, Harlan R., Ortutay, Csaba, Jänis, Janne, Laitaoja, Mikko, Hytönen, Vesa P., Azizi, Latifeh, Manandhar, Prajwol, Jáger, Edit, Vullo, Daniela, Kukkurainen, Sampo, Hilvo, Mika, Supuran, Claudiu T., Parkkila, Seppo
Publicado 2017