Update on psoriasis immunopathogenesis and targeted immunotherapy

por Mahil, Satveer K., Capon, Francesca, Barker, Jonathan N.
Publicado 2015

Psoriasis and other complex trait dermatoses: from loci to functional pathways

por Capon, Francesca, Burden, A David, Trembath, Richard C, Barker, Jonathan N
Publicado 2011

Psoriasis and Genetics

por DAND, Nick, MAHIL, Satveer K., CAPON, Francesca, SMITH, Catherine H., SIMPSON, Michael A., BARKER, Jonathan N.
Publicado 2020

Genetic Validation of Psoriasis Phenotyping in UK Biobank Supports the Utility of Self-Reported Data and Composite Definitions for Large Genetic and Epidemiological Studies

por Saklatvala, Jake R., Hanscombe, Ken B., Mahil, Satveer K., Tsoi, Lam C., Elder, James T., Barker, Jonathan N., Simpson, Michael A., Smith, Catherine H., Dand, Nick
Publicado 2023

The IL23R A/Gln381 Allele Promotes IL-23 Unresponsiveness in Human Memory T-Helper 17 Cells and Impairs Th17 Responses in Psoriasis Patients

por Di Meglio, Paola, Villanova, Federica, Napolitano, Luca, Tosi, Isabella, Terranova Barberio, Manuela, Mak, Rose K, Nutland, Sarah, Smith, Catherine H, Barker, Jonathan N W N, Todd, John A, Nestle, Frank O
Publicado 2013

Allele-specific cytokine responses at the HLA-C locus, implications for psoriasis

por Hundhausen, Christian, Bertoni, Anna, Mak, Rose K, Botti, Elisabetta, Di Meglio, Paola, Clop, Alex, Laggner, Ute, Chimenti, Sergio, Hayday, Adrian C, Barker, Jonathan N, Trembath, Richard C, Capon, Francesca, Nestle, Frank O
Publicado 2011

CYP1A1 Enzymatic Activity Influences Skin Inflammation Via Regulation of the AHR Pathway

por Kyoreva, Mariela, Li, Ying, Hoosenally, Mariyah, Hardman-Smart, Jonathan, Morrison, Kirsten, Tosi, Isabella, Tolaini, Mauro, Barinaga, Guillermo, Stockinger, Brigitta, Mrowietz, Ulrich, Nestle, Frank O., Smith, Catherine H., Barker, Jonathan N., Di Meglio, Paola
Publicado 2021

IL-36 Promotes Systemic IFN-I Responses in Severe Forms of Psoriasis

por Catapano, Marika, Vergnano, Marta, Romano, Marco, Mahil, Satveer K., Choon, Siew-Eng, Burden, A. David, Young, Helen S., Carr, Ian M., Lachmann, Helen J., Lombardi, Giovanna, Smith, Catherine H., Ciccarelli, Francesca D., Barker, Jonathan N., Capon, Francesca
Publicado 2020

An In-Depth Characterization of the Major Psoriasis Susceptibility Locus Identifies Candidate Susceptibility Alleles within an HLA-C Enhancer Element

por Clop, Alex, Bertoni, Anna, Spain, Sarah L., Simpson, Michael A., Pullabhatla, Venu, Tonda, Raul, Hundhausen, Christian, Di Meglio, Paola, De Jong, Pieter, Hayday, Adrian C., Nestle, Frank O., Barker, Jonathan N., Bell, Robert J. A., Capon, Francesca, Trembath, Richard C.
Publicado 2013

Application of information theoretic feature selection and machine learning methods for the development of genetic risk prediction models

por Jalali-najafabadi, Farideh, Stadler, Michael, Dand, Nick, Jadon, Deepak, Soomro, Mehreen, Ho, Pauline, Marzo-Ortega, Helen, Helliwell, Philip, Korendowych, Eleanor, Simpson, Michael A., Packham, Jonathan, Smith, Catherine H., Barker, Jonathan N., McHugh, Neil, Warren, Richard B., Barton, Anne, Bowes, John
Publicado 2021

Systematic review of deep learning image analyses for the diagnosis and monitoring of skin disease

por Choy, Shern Ping, Kim, Byung Jin, Paolino, Alexandra, Tan, Wei Ren, Lim, Sarah Man Lin, Seo, Jessica, Tan, Sze Ping, Francis, Luc, Tsakok, Teresa, Simpson, Michael, Barker, Jonathan N. W. N., Lynch, Magnus D., Corbett, Mark S., Smith, Catherine H., Mahil, Satveer K.
Publicado 2023

Phenome-wide association study using research participants’ self-reported data provides insight into the Th17 and IL-17 pathway

por Ehm, Margaret G., Aponte, Jennifer L., Chiano, Mathias N., Yerges-Armstrong, Laura M., Johnson, Toby, Barker, Jonathan N., Cook, Suzanne F., Gupta, Akanksha, Hinds, David A., Li, Li, Nelson, Matthew R., Simpson, Michael A., Tian, Chao, McCarthy, Linda C., Rajpal, Deepak K., Waterworth, Dawn M.
Publicado 2017

Humoral and cellular immunogenicity to a second dose of COVID-19 vaccine BNT162b2 in people receiving methotrexate or targeted immunosuppression: a longitudinal cohort study

por Mahil, Satveer K, Bechman, Katie, Raharja, Antony, Domingo-Vila, Clara, Baudry, David, Brown, Matthew A, Cope, Andrew P, Dasandi, Tejus, Graham, Carl, Khan, Hataf, Lechmere, Thomas, Malim, Michael H, Meynell, Freya, Pollock, Emily, Sychowska, Kamila, Barker, Jonathan N, Norton, Sam, Galloway, James B, Doores, Katie J, Tree, Timothy, Smith, Catherine H
Publicado 2021

The effect of methotrexate and targeted immunosuppression on humoral and cellular immune responses to the COVID-19 vaccine BNT162b2: a cohort study

por Mahil, Satveer K, Bechman, Katie, Raharja, Antony, Domingo-Vila, Clara, Baudry, David, Brown, Matthew A, Cope, Andrew P, Dasandi, Tejus, Graham, Carl, Lechmere, Thomas, Malim, Michael H, Meynell, Freya, Pollock, Emily, Seow, Jeffery, Sychowska, Kamila, Barker, Jonathan N, Norton, Sam, Galloway, James B, Doores, Katie J, Tree, Timothy I M, Smith, Catherine H
Publicado 2021

Enhanced NF-κB signaling in type-2 dendritic cells at baseline predicts non-response to adalimumab in psoriasis

por Andres-Ejarque, Rosa, Ale, Hira Bahadur, Grys, Katarzyna, Tosi, Isabella, Solanky, Shane, Ainali, Chrysanthi, Catak, Zeynep, Sreeneebus, Hemawtee, Saklatvala, Jake, Dand, Nick, de Rinaldis, Emanuele, Chapman, Anna, Nestle, Frank O., Barnes, Michael R., Warren, Richard B., Reynolds, Nick J., Griffiths, Christopher E. M., Barker, Jonathan N., Smith, Catherine H., Di Meglio, Paola
Publicado 2021

Author Correction: Enhanced NF-κB signaling in type-2 dendritic cells at baseline predicts non-response to adalimumab in psoriasis

por Andres-Ejarque, Rosa, Ale, Hira Bahadur, Grys, Katarzyna, Tosi, Isabella, Solanky, Shane, Ainali, Chrysanthi, Catak, Zeynep, Sreeneebus, Hemawtee, Saklatvala, Jake, Dand, Nick, de Rinaldis, Emanuele, Chapman, Anna, Nestle, Frank O., Barnes, Michael R., Warren, Richard B., Reynolds, Nick J., Griffiths, Christopher E. M., Barker, Jonathan N., Smith, Catherine H., Di Meglio, Paola
Publicado 2021

Genome-wide association meta-analysis identifies 29 new acne susceptibility loci

por Mitchell, Brittany L., Saklatvala, Jake R., Dand, Nick, Hagenbeek, Fiona A., Li, Xin, Min, Josine L., Thomas, Laurent, Bartels, Meike, Jan Hottenga, Jouke, Lupton, Michelle K., Boomsma, Dorret I., Dong, Xianjun, Hveem, Kristian, Løset, Mari, Martin, Nicholas G., Barker, Jonathan N., Han, Jiali, Smith, Catherine H., Rentería, Miguel E., Simpson, Michael A.
Publicado 2022

Biomarkers of systemic treatment response in people with psoriasis: a scoping review

por Corbett, Mark, Ramessur, Ravi, Marshall, David, Acencio, Marcio L., Ostaszewski, Marek, Barbosa, Ines A., Dand, Nick, Di Meglio, Paola, Haddad, Salma, Jensen, Andreas H.M., Koopmann, Witte, Mahil, Satveer K., Rahmatulla, Seher, Rastrick, Joe, Saklatvala, Jake, Weidinger, Stephan, Wright, Kath, Eyerich, Kilian, Barker, Jonathan N., Ndlovu, Matladi, Conrad, Curdin, Skov, Lone, Smith, Catherine H.
Publicado 2022

Biomarkers of disease progression in people with psoriasis: a scoping review

por Ramessur, Ravi, Corbett, Mark, Marshall, David, Acencio, Marcio L., Barbosa, Ines A., Dand, Nick, Di Meglio, Paola, Haddad, Salma, Jensen, Andreas H.M., Koopmann, Witte, Mahil, Satveer K., Ostaszewski, Marek, Rahmatulla, Seher, Rastrick, Joe, Saklatvala, Jake, Weidinger, Stephan, Wright, Kath, Eyerich, Kilian, Ndlovu, Matladi, Barker, Jonathan N., Skov, Lone, Conrad, Curdin, Smith, Catherine H
Publicado 2022

Cross-phenotype association mapping of the MHC identifies genetic variants that differentiate psoriatic arthritis from psoriasis

por Bowes, John, Ashcroft, James, Dand, Nick, Jalali-najafabadi, Farideh, Bellou, Eftychia, Ho, Pauline, Marzo-Ortega, Helena, Helliwell, Philip S, Feletar, Marie, Ryan, Anthony W, Kane, David J, Korendowych, Eleanor, Simpson, Michael A, Packham, Jonathan, McManus, Ross, Brown, Matthew A, Smith, Catherine H, Barker, Jonathan N, McHugh, Neil, FitzGerald, Oliver, Warren, Richard B, Barton, Anne
Publicado 2017