Quantifying Lgr5-positive stem cell behaviour in the pyloric epithelium

por Leushacke, Marc, Barker, Nick, Pin, Carmen
Publicado 2016

Targeted ablation of Lgr5-expressing intestinal stem cells in diphtheria toxin receptor-based mouse and organoid models

por Lim, Hui Yi Grace, Yada, Swathi, Barker, Nick
Publicado 2022

The Function of Lgr5(+) Cells in the Gastric Antrum Does Not Require Fzd7 or Myc In Vivo

por Flanagan, Dustin, Barker, Nick, Ernst, Matthias, Vincan, Elizabeth, Phesse, Toby
Publicado 2019

A Comprehensive Model of the Spatio-Temporal Stem Cell and Tissue Organisation in the Intestinal Crypt

por Buske, Peter, Galle, Jörg, Barker, Nick, Aust, Gabriela, Clevers, Hans, Loeffler, Markus
Publicado 2011

A genome-scale CRISPR screen reveals factors regulating Wnt-dependent renewal of mouse gastric epithelial cells

por Murakami, Kazuhiro, Terakado, Yumi, Saito, Kikue, Jomen, Yoshie, Takeda, Haruna, Oshima, Masanobu, Barker, Nick
Publicado 2021

Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo

por Flanagan, Dustin J., Barker, Nick, Nowell, Cameron, Clevers, Hans, Ernst, Matthias, Phesse, Toby J., Vincan, Elizabeth
Publicado 2017

Proteasome inhibitor bortezomib stabilizes and activates p53 in hematopoietic stem/progenitors and double-negative T cells in vivo

por Xue, Yuezhen, San Luis, Boris, Dress, Regine J., Murad, Katzrin Binte Ahmad, Ginhoux, Florent, Barker, Nick, Lane, David
Publicado 2023

p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium

por Cole, Alicia M, Ridgway, Rachel A, Derkits, Sahra E, Parry, Lee, Barker, Nick, Clevers, Hans, Clarke, Alan R, Sansom, Owen J
Publicado 2010

Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach

por Jangphattananont, Nawaphat, Sato, Hiroki, Imamura, Ryu, Sakai, Katsuya, Terakado, Yumi, Murakami, Kazuhiro, Barker, Nick, Oshima, Hiroko, Oshima, Masanobu, Takagi, Junichi, Kato, Yukinari, Yano, Seiji, Matsumoto, Kunio
Publicado 2019

Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development

por Seishima, Ryo, Leung, Carly, Yada, Swathi, Murad, Katzrin Bte Ahmed, Tan, Liang Thing, Hajamohideen, Amin, Tan, Si Hui, Itoh, Hideki, Murakami, Kazuhiro, Ishida, Yoshihiro, Nakamizo, Satoshi, Yoshikawa, Yusuke, Wong, Esther, Barker, Nick
Publicado 2019

Mutant p53 accumulates in cycling and proliferating cells in the normal tissues of p53 R172H mutant mice

por Goh, Amanda M., Xue, Yuezhen, Leushacke, Marc, Li, Ling, Wong, Julin S., Chiam, Poh Cheang, Rahmat, Siti Aishah Binte, Mann, Michael B., Mann, Karen M., Barker, Nick, Lozano, Guillermina, Terzian, Tamara, Lane, David P.
Publicado 2015

Frizzled7 Functions as a Wnt Receptor in Intestinal Epithelial Lgr5(+) Stem Cells

por Flanagan, Dustin J., Phesse, Toby J., Barker, Nick, Schwab, Renate H.M., Amin, Nancy, Malaterre, Jordane, Stange, Daniel E., Nowell, Cameron J., Currie, Scott A., Saw, Jarel T.S., Beuchert, Eva, Ramsay, Robert G., Sansom, Owen J., Ernst, Matthias, Clevers, Hans, Vincan, Elizabeth
Publicado 2015

E-cadherin can limit the transforming properties of activating β-catenin mutations

por Huels, David J, Ridgway, Rachel A, Radulescu, Sorina, Leushacke, Marc, Campbell, Andrew D, Biswas, Sujata, Leedham, Simon, Serra, Stefano, Chetty, Runjan, Moreaux, Guenievre, Parry, Lee, Matthews, James, Song, Fei, Hedley, Ann, Kalna, Gabriela, Ceteci, Fatih, Reed, Karen R, Meniel, Valerie S, Maguire, Aoife, Doyle, Brendan, Söderberg, Ola, Barker, Nick, Watson, Alastair, Larue, Lionel, Clarke, Alan R, Sansom, Owen J
Publicado 2015

Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma

por Cammareri, Patrizia, Rose, Aidan M., Vincent, David F., Wang, Jun, Nagano, Ai, Libertini, Silvana, Ridgway, Rachel A., Athineos, Dimitris, Coates, Philip J., McHugh, Angela, Pourreyron, Celine, Dayal, Jasbani H. S., Larsson, Jonas, Weidlich, Simone, Spender, Lindsay C., Sapkota, Gopal P., Purdie, Karin J., Proby, Charlotte M., Harwood, Catherine A., Leigh, Irene M., Clevers, Hans, Barker, Nick, Karlsson, Stefan, Pritchard, Catrin, Marais, Richard, Chelala, Claude, South, Andrew P., Sansom, Owen J., Inman, Gareth J.
Publicado 2016