Glia in FTLD-GRN: from supporting cast to leading role

por Pinarbasi, Emile S., Barmada, Sami J.
Publicado 2023

Matrin 3 in neuromuscular disease: physiology and pathophysiology

por Malik, Ahmed M., Barmada, Sami J.
Publicado 2021

Autophagy and ALS: mechanistic insights and therapeutic implications

por Chua, Jason P., De Calbiac, Hortense, Kabashi, Edor, Barmada, Sami J.
Publicado 2021

An Intramolecular Salt Bridge Linking TDP43 RNA Binding, Protein Stability, and TDP43-Dependent Neurodegeneration

por Flores, Brittany N., Li, Xingli, Malik, Ahmed M., Martinez, Jose, Beg, Asim A., Barmada, Sami J.
Publicado 2019

Enhanced detection of expanded repeat mRNA foci with hybridization chain reaction

por Glineburg, M. Rebecca, Zhang, Yuan, Krans, Amy, Tank, Elizabeth M., Barmada, Sami J., Todd, Peter K.
Publicado 2021

Development of a specific live-cell assay for native autophagic flux

por Safren, Nathaniel, Tank, Elizabeth M., Malik, Ahmed M., Chua, Jason P., Santoro, Nicholas, Barmada, Sami J.
Publicado 2021

Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization

por Malik, Ahmed M, Miguez, Roberto A, Li, Xingli, Ho, Ye-Shih, Feldman, Eva L, Barmada, Sami J
Publicado 2018

TorsinA is essential for the timing and localization of neuronal nuclear pore complex biogenesis

por Kim, Sumin, Phan, Sébastien, Shaw, Thomas R., Ellisman, Mark H., Veatch, Sarah L., Barmada, Sami J., Pappas, Samuel S., Dauer, William T.
Publicado 2023

The carboxyl termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD

por He, Fang, Flores, Brittany N., Krans, Amy, Frazer, Michelle, Natla, Sam, Niraula, Sarjina, Adefioye, Olamide, Barmada, Sami J., Todd, Peter K.
Publicado 2020

Distinct C9orf72-Associated Dipeptide Repeat Structures Correlate with Neuronal Toxicity

por Flores, Brittany N., Dulchavsky, Mark E., Krans, Amy, Sawaya, Michael R., Paulson, Henry L., Todd, Peter K., Barmada, Sami J., Ivanova, Magdalena I.
Publicado 2016

Overexpression of the essential Sis1 chaperone reduces TDP-43 effects on toxicity and proteolysis

por Park, Sei-Kyoung, Hong, Joo Y., Arslan, Fatih, Kanneganti, Vydehi, Patel, Basant, Tietsort, Alex, Tank, Elizabeth M. H., Li, Xingli, Barmada, Sami J., Liebman, Susan W.
Publicado 2017

RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response

por Green, Katelyn M., Glineburg, M. Rebecca, Kearse, Michael G., Flores, Brittany N., Linsalata, Alexander E., Fedak, Stephen J., Goldstrohm, Aaron C., Barmada, Sami J., Todd, Peter K.
Publicado 2017

Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models

por Barmada, Sami J., Serio, Andrea, Arjun, Arpana, Bilican, Bilada, Daub, Aaron, Ando, D. Michael, Tsvetkov, Andrey, Pleiss, Michael, Li, Xingli, Peisach, Daniel, Shaw, Christopher, Chandran, Siddharthan, Finkbeiner, Steven
Publicado 2014

Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury

por Martens, Lauren Herl, Zhang, Jiasheng, Barmada, Sami J., Zhou, Ping, Kamiya, Sherry, Sun, Binggui, Min, Sang-Won, Gan, Li, Finkbeiner, Steven, Huang, Eric J., Jr, Robert V. Farese
Publicado 2022

CGG repeats trigger translational frameshifts that generate aggregation-prone chimeric proteins

por Wright, Shannon E, Rodriguez, Caitlin M, Monroe, Jeremy, Xing, Jiazheng, Krans, Amy, Flores, Brittany N, Barsur, Venkatesha, Ivanova, Magdalena I, Koutmou, Kristin S, Barmada, Sami J, Todd, Peter K
Publicado 2022

Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats

por Tseng, Yi-Ju, Malik, Indranil, Deng, Xiexiong, Krans, Amy, Jansen-West, Karen, Tank, Elizabeth M.H., Gomez, Nicolas B., Sher, Roger, Petrucelli, Leonard, Barmada, Sami J., Todd, Peter K.
Publicado 2023

TDP43 nuclear export and neurodegeneration in models of amyotrophic lateral sclerosis and frontotemporal dementia

por Archbold, Hilary C., Jackson, Kasey L., Arora, Ayush, Weskamp, Kaitlin, Tank, Elizabeth M.-H., Li, Xingli, Miguez, Roberto, Dayton, Robert D., Tamir, Sharon, Klein, Ronald L., Barmada, Sami J.
Publicado 2018

Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models

por Armakola, Maria, Higgins, Matthew J., Figley, Matthew D., Barmada, Sami J., Scarborough, Emily A., Diaz, Zamia, Fang, Xiaodong, Shorter, James, Krogan, Nevan J., Finkbeiner, Steven, Farese, Robert V., Gitler, Aaron D.
Publicado 2012

Cytoplasmic TDP43 Binds microRNAs: New Disease Targets in Amyotrophic Lateral Sclerosis

por Paez-Colasante, Ximena, Figueroa-Romero, Claudia, Rumora, Amy E., Hur, Junguk, Mendelson, Faye E., Hayes, John M., Backus, Carey, Taubman, Ghislaine F., Heinicke, Laurie, Walter, Nils G., Barmada, Sami J., Sakowski, Stacey A., Feldman, Eva L.
Publicado 2020

Ubiquilin-2 regulates pathological alpha-synuclein

por Sandoval-Pistorius, Stephanie S., Gerson, Julia E., Liggans, Nyjerus, Ryou, Jaimie H., Oak, Kulin, Li, Xingli, Negron-Rios, Keyshla Y., Fischer, Svetlana, Barsh, Henry, Crowley, Emily V., Skinner, Mary E., Sharkey, Lisa M., Barmada, Sami J., Paulson, Henry L.
Publicado 2023