Validation of memory assessment in the Starmaze task: Data from 14 month-old APPPS1 mice and controls

por Schmitt, Julien, Paradis, Anne-Lise, Boucher, Mathieu, Andrieu, Laurent, Barnéoud, Pascal, Rondi-Reig, Laure
Publicado 2021

Data on synthesis, ADME and pharmacological properties and early safety pharmacology evaluation of a series of novel NURR1/NOT agonist potentially useful for the treatment of Parki...

por Malanda, André, Abécassis, Pierre-Yves, Barnéoud, Pascal, Brunel, Pascale, Taupin, Véronique, Vigé, Xavier, Lesuisse, Dominique
Publicado 2019

Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity

por Nguyen, An Phu Tran, Tsika, Elpida, Kelly, Kaela, Levine, Nathan, Chen, Xi, West, Andrew B., Boularand, Sylviane, Barneoud, Pascal, Moore, Darren J.
Publicado 2020

A Nurr1 Agonist Causes Neuroprotection in a Parkinson’s Disease Lesion Model Primed with the Toll-Like Receptor 3 dsRNA Inflammatory Stimulant Poly(I:C)

por Smith, Gaynor A., Rocha, Emily M., Rooney, Thomas, Barneoud, Pascal, McLean, Jesse R., Beagan, Jonathan, Osborn, Teresia, Coimbra, Madeleine, Luo, Yongyi, Hallett, Penelope J., Isacson, Ole
Publicado 2015

SAR110894, a potent histamine H3-receptor antagonist, displays disease-modifying activity in a transgenic mouse model of tauopathy

por Delay-Goyet, Philippe, Blanchard, Véronique, Schussler, Nathalie, Lopez-Grancha, Mati, Ménager, Jean, Mary, Véronique, Sultan, Eric, Buzy, Armelle, Guillemot, Jean-Claude, Stemmelin, Jeanne, Bertrand, Philippe, Rooney, Thomas, Pradier, Laurent, Barnéoud, Pascal
Publicado 2016

Gene delivery of a modified antibody to Aβ reduces progression of murine Alzheimer’s disease

por Elmer, Bradford M., Swanson, Kurt A., Bangari, Dinesh S., Piepenhagen, Peter A., Roberts, Errin, Taksir, Tatyana, Guo, Lei, Obinu, Maria-Carmen, Barneoud, Pascal, Ryan, Susan, Zhang, Bailin, Pradier, Laurent, Yang, Zhi-Yong, Nabel, Gary J.
Publicado 2019

SAR228810: an antibody for protofibrillar amyloid β peptide designed to reduce the risk of amyloid-related imaging abnormalities (ARIA)

por Pradier, Laurent, Blanchard-Brégeon, Véronique, Bohme, Andrees, Debeir, Thomas, Menager, Jean, Benoit, Patrick, Barneoud, Pascal, Taupin, Véronique, Bertrand, Philippe, Dugay, Philippe, Cameron, Béatrice, Shi, Yi, Naimi, Souad, Duchesne, Marc, Gagnaire, Marie, Weeden, Tim, Travaline, Tara, Reczek, David, Khiroug, Leonard, Slaoui, Mohamed, Brunel, Pascale, Fukuyama, Hidehiro, Ravetch, Jeffrey, Canton, Thierry, Cohen, Caroline
Publicado 2018