When Clocks Go Bad: Neurobehavioural Consequences of Disrupted Circadian Timing

por Barnard, Alun R., Nolan, Patrick M.
Publicado 2008


Gene Therapy for Color Blindness

por Hassall, Mark M., Barnard, Alun R., MacLaren, Robert E.
Publicado 2017

Molecular Therapies for Choroideremia

por Cehajic Kapetanovic, Jasmina, Barnard, Alun R., MacLaren, Robert E.
Publicado 2019

Assessment of AAV Dual Vector Safety in the Abca4(−)(/)(−) Mouse Model of Stargardt Disease

por McClements, Michelle E., Barnard, Alun R., Charbel Issa, Peter, MacLaren, Robert E.
Publicado 2020

The Biological Activity of AAV Vectors for Choroideremia Gene Therapy Can Be Measured by In Vitro Prenylation of RAB6A

por Patrício, Maria I., Barnard, Alun R., Cox, Christopher I., Blue, Clare, MacLaren, Robert E.
Publicado 2018

Inclusion of the Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element Enhances AAV2-Driven Transduction of Mouse and Human Retina

por Patrício, Maria I., Barnard, Alun R., Orlans, Harry O., McClements, Michelle E., MacLaren, Robert E.
Publicado 2017

RNA Editing as a Therapeutic Approach for Retinal Gene Therapy Requiring Long Coding Sequences

por Fry, Lewis E., Peddle, Caroline F., Barnard, Alun R., McClements, Michelle E., MacLaren, Robert E.
Publicado 2020

Impact of Vital Dyes on Cell Viability and Transduction Efficiency of AAV Vectors Used in Retinal Gene Therapy Surgery: An In Vitro and In Vivo Analysis

por Salvetti, Anna P., Patrício, Maria I., Barnard, Alun R., Orlans, Harry O., Hickey, Doron G., MacLaren, Robert E.
Publicado 2017

Immunomodulatory Effects of Hydroxychloroquine and Chloroquine in Viral Infections and Their Potential Application in Retinal Gene Therapy

por Chandler, Laurel C., Yusuf, Imran H., McClements, Michelle E., Barnard, Alun R., MacLaren, Robert E., Xue, Kanmin
Publicado 2020

Analysis of Early Cone Dysfunction in an In Vivo Model of Rod-Cone Dystrophy

por Hassall, Mark M., McClements, Michelle E., Barnard, Alun R., Patrício, Maria I., Aslam, Sher A., Maclaren, Robert E.
Publicado 2020

Non-Image-Forming Light Driven Functions Are Preserved in a Mouse Model of Autosomal Dominant Optic Atrophy

por Perganta, Georgia, Barnard, Alun R., Katti, Christiana, Vachtsevanos, Athanasios, Douglas, Ron H., MacLaren, Robert E., Votruba, Marcela, Sekaran, Sumathi
Publicado 2013

Mirtron-mediated RNA knockdown/replacement therapy for the treatment of dominant retinitis pigmentosa

por Orlans, Harry O., McClements, Michelle E., Barnard, Alun R., Martinez-Fernandez de la Camara, Cristina, MacLaren, Robert E.
Publicado 2021

Inclusion of PF68 Surfactant Improves Stability of rAAV Titer when Passed through a Surgical Device Used in Retinal Gene Therapy

por Patrício, Maria I., Cox, Christopher I., Blue, Clare, Barnard, Alun R., Martinez-Fernandez de la Camara, Cristina, MacLaren, Robert E.
Publicado 2019

Functional expression of complement factor I following AAV-mediated gene delivery in the retina of mice and human cells

por Dreismann, Anna K., McClements, Michelle E., Barnard, Alun R., Orhan, Elise, Hughes, Jane P., Lachmann, Peter J., MacLaren, Robert E.
Publicado 2021

Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion

por Singh, Mandeep S., Balmer, Jasmin, Barnard, Alun R., Aslam, Sher A., Moralli, Daniela, Green, Catherine M., Barnea-Cramer, Alona, Duncan, Isabel, MacLaren, Robert E.
Publicado 2016

The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification

por Cross, Sally H., Mckie, Lisa, Hurd, Toby W., Riley, Sam, Wills, Jimi, Barnard, Alun R., Young, Fiona, MacLaren, Robert E., Jackson, Ian J.
Publicado 2020

Functional expression of Rab escort protein 1 following AAV2-mediated gene delivery in the retina of choroideremia mice and human cells ex vivo

por Tolmachova, Tanya, Tolmachov, Oleg E., Barnard, Alun R., de Silva, Samantha R., Lipinski, Daniel M., Walker, Nathan J., MacLaren, Robert E., Seabra, Miguel C.
Publicado 2013

Enhancement of Adeno-Associated Virus-Mediated Gene Therapy Using Hydroxychloroquine in Murine and Human Tissues

por Chandler, Laurel C., Barnard, Alun R., Caddy, Sarah L., Patrício, Maria I., McClements, Michelle E., Fu, Howell, Rada, Cristina, MacLaren, Robert E., Xue, Kanmin
Publicado 2019

Enhancement of Adeno-Associated Virus-Mediated Gene Therapy Using Hydroxychloroquine in Murine and Human Tissues

por Chandler, Laurel C., Barnard, Alun R., Caddy, Sarah L., Patrício, Maria I., McClements, Michelle E., Fu, Howell, Rada, Cristina, MacLaren, Robert E., Xue, Kanmin
Publicado 2023

Function of human pluripotent stem cell-derived photoreceptor progenitors in blind mice

por Barnea-Cramer, Alona O., Wang, Wei, Lu, Shi-Jiang, Singh, Mandeep S., Luo, Chenmei, Huo, Hongguang, McClements, Michelle E., Barnard, Alun R., MacLaren, Robert E., Lanza, Robert
Publicado 2016