ROS is a master regulator of in vitro matriptase activation

por Gaymon, Darius O., Barndt, Robert, Stires, Hillary, Riggins, Rebecca B., Johnson, Michael. D.
Publicado 2023

Modeling of dilated cardiomyopathy by establishment of isogenic human iPSC lines carrying phospholamban C25T (R9C) mutation (UPITTi002-A-1) using CRISPR/Cas9 editing

por Barndt, Robert J., Ma, Ning, Tang, Ying, Haugh, Michael P., Alamri, Laila S., Chan, Stephen Y., Wu, Haodi
Publicado 2021

Metabolic Maturation Exaggerates Abnormal Calcium Handling in a Lamp2 Knockout Human Pluripotent Stem Cell-Derived Cardiomyocyte Model of Danon Disease

por Barndt, Robert J., Liu, Qing, Tang, Ying, Haugh, Michael P., Cui, Jeffery, Chan, Stephen Y., Wu, Haodi
Publicado 2022

Matriptase shedding is closely coupled with matriptase zymogen activation and requires de novo proteolytic cleavage likely involving its own activity

por Tseng, Chun-Che, Jia, Bailing, Barndt, Robert, Gu, Yayun, Chen, Chien-Yu, Tseng, I-Chu, Su, Sheng-Fang, Wang, Jehng-Kang, Johnson, Michael D., Lin, Chen-Yong
Publicado 2017

Selective Inhibition of Prostasin in Human Enterocytes by the Integral Membrane Kunitz-Type Serine Protease Inhibitor HAI-2

por Shiao, Frank, Liu, Li-Ching O., Huang, Nanxi, Lai, Ying-Jung J., Barndt, Robert J., Tseng, Chun-Che, Wang, Jehng-Kang, Jia, Bailing, Johnson, Michael D., Lin, Chen-Yong
Publicado 2017

The intracellular seven amino acid motif EEGEVFL is required for matriptase vesicle sorting and translocation to the basolateral plasma membrane

por Tseng, Chun-Che, Jia, Bailing, Barndt, Robert B., Dai, Yang-Hong, Chen, Yu Hsin, Du, Po-Wen A., Wang, Jehng-Kang, Tang, Hung-Jen, Lin, Chen-Yong, Johnson, Michael D.
Publicado 2020

Differential subcellular distribution renders HAI-2 a less effective protease inhibitor than HAI-1 in the control of extracellular matriptase proteolytic activity

por Chiu, Yi-Lin, Wu, Yi-Ying, Barndt, Robert B., Lin, Yu-Wen, Sytwo, Hou-Ping, Cheng, Amy, Yang, Kacy, Chan, Khee-Siang, Wang, Jehng-Kang, Johnson, Michael D., Lin, Chen-Yong
Publicado 2020

Aberrant regulation favours matriptase proteolysis in neoplastic B-cells that co-express HAI-2

por Chiu, Yi-Lin, Wu, Yi-Ying, Barndt, Robert B., Yeo, Yee Hui, Lin, Yu-Wen, Sytwo, Hou-Ping, Liu, Huan-Cheng, Xu, Yuan, Jia, Bailing, Wang, Jehng-Kang, Johnson, Michael D., Lin, Chen-Yong
Publicado 2019

Matriptase regulates proliferation and early, but not terminal, differentiation of human keratinocytes

por Chen, Ya-Wen, Wang, Jehng-Kang, Chou, Fen-Pai, Wu, Bai-Yao, Hsiao, Hui-Chung, Chiu, Han, Xu, Zhonghong, Baksh, Adrienne NH, Shi, Galen, Kaul, Malvika, Barndt, Robert, Shanmugam, Victoria K., Johnson, Michael D., Lin, Chen-Yong
Publicado 2013

Natural Endogenous Human Matriptase and Prostasin Undergo Zymogen Activation via Independent Mechanisms in an Uncoupled Manner

por Su, Hui Chen, Liang, Yan A., Lai, Ying-Jung J., Chiu, Yi-Lin, Barndt, Robert B., Shiao, Frank, Chang, Hsiang-Hua D., Lu, Dajun D., Huang, Nanxi, Tseng, Chun-Che, Wang, Jehng-Kang, Lee, Ming-Shyue, Johnson, Michael D., Huang, Shih-Ming, Lin, Chen-Yong
Publicado 2016