Pharmacologic Activation of a Compensatory Integrated Stress Response Kinase Promotes Mitochondrial Remodeling in PERK-deficient Cells

por Perea, Valerie, Baron, Kelsey R., Dolina, Vivian, Aviles, Giovanni, Rosarda, Jessica D., Guo, Xiaoyan, Kampmann, Martin, Wiseman, R. Luke
Publicado 2023

PERK signaling promotes mitochondrial elongation by remodeling membrane phosphatidic acid

por Perea, Valerie, Cole, Christian, Lebeau, Justine, Dolina, Vivian, Baron, Kelsey R, Madhavan, Aparajita, Kelly, Jeffery W, Grotjahn, Danielle A, Wiseman, R Luke
Publicado 2023

Metabolically Activated Proteostasis Regulators Protect against Glutamate Toxicity by Activating NRF2

por Rosarda, Jessica D., Baron, Kelsey R., Nutsch, Kayla, Kline, Gabriel M., Stanton, Caroline, Kelly, Jeffery W., Bollong, Michael J., Wiseman, R. Luke
Publicado 2021