Use of a charge reducing agent to enable intact mass analysis of cysteine-linked antibody-drug-conjugates by native mass spectrometry

por Pacholarz, Kamila J., Barran, Perdita E.
Publicado 2016

Charge Mediated Compaction and Rearrangement of Gas-Phase Proteins: A Case Study Considering Two Proteins at Opposing Ends of the Structure-Disorder Continuum

por Jhingree, Jacquelyn R., Bellina, Bruno, Pacholarz, Kamila J., Barran, Perdita E.
Publicado 2017

Initial Protein Unfolding Events in Ubiquitin, Cytochrome c and Myoglobin Are Revealed with the Use of 213 nm UVPD Coupled to IM-MS

por Theisen, Alina, Black, Rachelle, Corinti, Davide, Brown, Jeffery M., Bellina, Bruno, Barran, Perdita E.
Publicado 2018

DNA Binding and Phosphorylation Regulate the Core Structure of the NF-κB p50 Transcription Factor

por Vonderach, Matthias, Byrne, Dominic P., Barran, Perdita E., Eyers, Patrick A., Eyers, Claire E.
Publicado 2018

Sizing and Discovery of Nanosized Polyoxometalate Clusters by Mass Spectrometry

por Surman, Andrew J., Robbins, Philip J., Ujma, Jakub, Zheng, Qi, Barran, Perdita. E., Cronin, Leroy
Publicado 2016

Relating gas phase to solution conformations: Lessons from disordered proteins

por Beveridge, Rebecca, Phillips, Ashley S., Denbigh, Laetitia, Saleem, Hassan M., MacPhee, Cait E., Barran, Perdita E.
Publicado 2015

Mass spectrometry locates local and allosteric conformational changes that occur on cofactor binding

por Beveridge, Rebecca, Migas, Lukasz G., Payne, Karl A. P., Scrutton, Nigel S., Leys, David, Barran, Perdita E.
Publicado 2016

Cold Denaturation of Proteins in the Absence of Solvent: Implications for Protein Storage

por Norgate, Emma L., Upton, Rosie, Hansen, Kjetil, Bellina, Bruno, Brookes, C., Politis, Argyris, Barran, Perdita E.
Publicado 2022

Ion Mobility Mass Spectrometry Uncovers the Impact of the Patterning of Oppositely Charged Residues on the Conformational Distributions of Intrinsically Disordered Proteins

por Beveridge, Rebecca, Migas, Lukasz G., Das, Rahul K., Pappu, Rohit V., Kriwacki, Richard W., Barran, Perdita E.
Publicado 2019

The complexity of selection at the major primate β-defensin locus

por Semple, Colin AM, Maxwell, Alison, Gautier, Philippe, Kilanowski, Fiona M, Eastwood, Hayden, Barran, Perdita E, Dorin, Julia R
Publicado 2005

The use of ion mobility mass spectrometry to probe modulation of the structure of p53 and of MDM2 by small molecule inhibitors

por Dickinson, Eleanor R., Jurneczko, Ewa, Nicholson, Judith, Hupp, Ted R., Zawacka-Pankau, Joanna, Selivanova, Galina, Barran, Perdita E.
Publicado 2015

Hybrid mass spectrometry methods reveal lot-to-lot differences and delineate the effects of glycosylation on the tertiary structure of Herceptin®

por Upton, Rosie, Migas, Lukasz G., Pacholarz, Kamila J., Beniston, Richard G., Estdale, Sian, Firth, David, Barran, Perdita E.
Publicado 2019

Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches

por Jeffreys, Laura N., Pacholarz, Kamila J., Johannissen, Linus O., Girvan, Hazel M., Barran, Perdita E., Voice, Michael W., Munro, Andrew W.
Publicado 2020

Consequences of point mutations in melanoma-associated antigen 4 (MAGE-A4) protein: Insights from structural and biophysical studies

por Hagiwara, Yoshio, Sieverling, Lina, Hanif , Farina, Anton, Jensy, Dickinson, Eleanor R., Bui, Tam T. T., Andreeva, Antonina, Barran, Perdita E., Cota, Ernesto, Nikolova, Penka V.
Publicado 2016

Coupling Droplet Microfluidics with Mass Spectrometry for Ultrahigh-Throughput Analysis of Complex Mixtures up to and above 30 Hz

por Kempa, Emily E., Smith, Clive A., Li, Xin, Bellina, Bruno, Richardson, Keith, Pringle, Steven, Galman, James L., Turner, Nicholas J., Barran, Perdita E.
Publicado 2020

Identification and proteomic profiling of exosomes in human cerebrospinal fluid

por Street, Jonathan M, Barran, Perdita E, Mackay, C Logan, Weidt, Stefan, Balmforth, Craig, Walsh, Tim S, Chalmers, Rod TA, Webb, David J, Dear, James W
Publicado 2012

Interplay between chromophore binding and domain assembly by the B(12)-dependent photoreceptor protein, CarH

por Camacho, Inês S., Black, Rachelle, Heyes, Derren J., Johannissen, Linus O., Ramakers, Lennart A. I., Bellina, Bruno, Barran, Perdita E., Hay, Sam, Jones, Alex R.
Publicado 2021

Uncoupling conformational states from activity in an allosteric enzyme

por Pisco, João P., de Chiara, Cesira, Pacholarz, Kamila J., Garza-Garcia, Acely, Ogrodowicz, Roksana W., Walker, Philip A., Barran, Perdita E., Smerdon, Stephen J., de Carvalho, Luiz Pedro S.
Publicado 2017

Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation

por Macpherson, Jamie A, Theisen, Alina, Masino, Laura, Fets, Louise, Driscoll, Paul C, Encheva, Vesela, Snijders, Ambrosius P, Martin, Stephen R, Kleinjung, Jens, Barran, Perdita E, Fraternali, Franca, Anastasiou, Dimitrios
Publicado 2019

Adduct Ions as Diagnostic Probes of Metallosupramolecular Complexes Using Ion Mobility Mass Spectrometry

por Geue, Niklas, Bennett, Tom S., Ramakers, Lennart A. I., Timco, Grigore A., McInnes, Eric J. L., Burton, Neil A., Armentrout, P. B., Winpenny, Richard E. P., Barran, Perdita E.
Publicado 2023