Genetic risk prediction in complex disease

por Jostins, Luke, Barrett, Jeffrey C.
Publicado 2011

Variation at Spike position 142 in SARS-CoV-2 Delta genomes is a technical artifact caused by dropout of a sequencing amplicon

por Sanderson, Theo, Barrett, Jeffrey C.
Publicado 2021

Olorin: combining gene flow with exome sequencing in large family studies of complex disease

por Morris, James A., Barrett, Jeffrey C.
Publicado 2012

Strategies for fine-mapping complex traits

por Spain, Sarah L., Barrett, Jeffrey C.
Publicado 2015

Synthetic associations in the context of genome-wide association scan signals

por Orozco, Gisela, Barrett, Jeffrey C., Zeggini, Eleftheria
Publicado 2010

Using Genetic Prediction from Known Complex Disease Loci to Guide the Design of Next-Generation Sequencing Experiments

por Jostins, Luke, Levine, Adam P., Barrett, Jeffrey C.
Publicado 2013

Synthetic Associations Are Unlikely to Account for Many Common Disease Genome-Wide Association Signals

por Anderson, Carl A., Soranzo, Nicole, Zeggini, Eleftheria, Barrett, Jeffrey C.
Publicado 2011

Characterization of Expression Quantitative Trait Loci in the Human Colon

por Singh, Tarjinder, Levine, Adam P., Smith, Philip J., Smith, Andrew M., Segal, Anthony W., Barrett, Jeffrey C.
Publicado 2015

Returning genome sequences to research participants: Policy and practice

por Wright, Caroline F., Middleton, Anna, Barrett, Jeffrey C., Firth, Helen V., FitzPatrick, David R., Hurles, Matthew E., Parker, Michael
Publicado 2017

Genetic Complexity of Crohn’s Disease in Two Large Ashkenazi Jewish Families

por Levine, Adam P., Pontikos, Nikolas, Schiff, Elena R., Jostins, Luke, Speed, Doug, Lovat, Laurence B., Barrett, Jeffrey C., Grasberger, Helmut, Plagnol, Vincent, Segal, Anthony W.
Publicado 2016

Exome-wide assessment of the functional impact and pathogenicity of multinucleotide mutations

por Kaplanis, Joanna, Akawi, Nadia, Gallone, Giuseppe, McRae, Jeremy F., Prigmore, Elena, Wright, Caroline F., Fitzpatrick, David R., Firth, Helen V., Barrett, Jeffrey C., Hurles, Matthew E.
Publicado 2019

Genetic association of fetal-hemoglobin levels in individuals with sickle cell disease in Tanzania maps to conserved regulatory elements within the MYB core enhancer

por Mtatiro, Siana N, Mgaya, Josephine, Singh, Tarjinder, Mariki, Harvest, Rooks, Helen, Soka, Deogratius, Mmbando, Bruno, Thein, Swee Lay, Barrett, Jeffrey C, Makani, Julie, Cox, Sharon E, Menzel, Stephan
Publicado 2015

Genome Wide Association Study of Fetal Hemoglobin in Sickle Cell Anemia in Tanzania

por Mtatiro, Siana Nkya, Singh, Tarjinder, Rooks, Helen, Mgaya, Josephine, Mariki, Harvest, Soka, Deogratius, Mmbando, Bruno, Msaki, Evarist, Kolder, Iris, Thein, Swee Lay, Menzel, Stephan, Cox, Sharon E., Makani, Julie, Barrett, Jeffrey C.
Publicado 2014

Atlas of plasma NMR biomarkers for health and disease in 118,461 individuals from the UK Biobank

por Julkunen, Heli, Cichońska, Anna, Tiainen, Mika, Koskela, Harri, Nybo, Kristian, Mäkelä, Valtteri, Nokso-Koivisto, Jussi, Kristiansson, Kati, Perola, Markus, Salomaa, Veikko, Jousilahti, Pekka, Lundqvist, Annamari, Kangas, Antti J., Soininen, Pasi, Barrett, Jeffrey C., Würtz, Peter
Publicado 2023

Exome Sequencing and Genotyping Identify a Rare Variant in NLRP7 Gene Associated With Ulcerative Colitis

por Onoufriadis, Alexandros, Stone, Kristina, Katsiamides, Antreas, Amar, Ariella, Omar, Yasmin, de Lange, Katrina M, Taylor, Kirstin, Barrett, Jeffrey C, Pollok, Richard, Hayee, Bu’Hussain, Mansfield, John C, Sanderson, Jeremy D, Simpson, Michael A, Mathew, Christopher G, Prescott, Natalie J
Publicado 2018

Genome-wide association study and meta-analysis finds over 40 loci affect risk of type 1 diabetes

por Barrett, Jeffrey C., Clayton, David, Concannon, Patrick, Akolkar, Beena, Cooper, Jason D., Erlich, Henry A., Julier, Cécile, Morahan, Grant, Nerup, Jørn, Nierras, Concepcion, Plagnol, Vincent, Pociot, Flemming, Schuilenburg, Helen, Smyth, Deborah J., Stevens, Helen, Todd, John A., Walker, Neil M., Rich, Stephen S.
Publicado 2009

An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci

por Mountjoy, Edward, Schmidt, Ellen M., Carmona, Miguel, Schwartzentruber, Jeremy, Peat, Gareth, Miranda, Alfredo, Fumis, Luca, Hayhurst, James, Buniello, Annalisa, Karim, Mohd Anisul, Wright, Daniel, Hercules, Andrew, Papa, Eliseo, Fauman, Eric B., Barrett, Jeffrey C., Todd, John A., Ochoa, David, Dunham, Ian, Ghoussaini, Maya
Publicado 2021

High-throughput and quantitative genome-wide messenger RNA sequencing for molecular phenotyping

por Collins, John E., Wali, Neha, Sealy, Ian M., Morris, James A., White, Richard J., Leonard, Steven R., Jackson, David K., Jones, Matthew C., Smerdon, Nathalie C., Zamora, Jorge, Dooley, Christopher M., Carruthers, Samantha N., Barrett, Jeffrey C., Stemple, Derek L., Busch-Nentwich, Elisabeth M.
Publicado 2015

Making new genetic diagnoses with old data: iterative reanalysis and reporting from genome-wide data in 1133 families with developmental disorders

por Wright, Caroline F., McRae, Jeremy F., Clayton, Stephen, Gallone, Giuseppe, Aitken, Stuart, FitzGerald, Tomas W., Jones, Philip, Prigmore, Elena, Rajan, Diana, Lord, Jenny, Sifrim, Alejandro, Kelsell, Rosemary, Parker, Michael J., Barrett, Jeffrey C., Hurles, Matthew E., FitzPatrick, David R., Firth, Helen V.
Publicado 2018

Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration

por Curtis, James, Luo, Yang, Zenner, Helen L., Cuchet-Lourenço, Delphine, Wu, Changxin, Lo, Kitty, Maes, Mailis, Alisaac, Ali, Stebbings, Emma, Liu, Jimmy Z., Kopanitsa, Liliya, Ignatyeva, Olga, Balabanova, Yanina, Nikolayevskyy, Vladyslav, Baessmann, Ingelore, Thye, Thorsten, Meyer, Christian G., Nürnberg, Peter, Horstmann, Rolf D., Drobniewski, Francis, Plagnol, Vincent, Barrett, Jeffrey C., Nejentsev, Sergey
Publicado 2015