Stabilizing Additives Added during Cell Lysis Aid in the Solubilization of Recombinant Proteins

por Leibly, David J., Nguyen, Trang Nhu, Kao, Louis T., Hewitt, Stephen N., Barrett, Lynn K., Van Voorhis, Wesley C.
Publicado 2012

Evaluation of in vitro and in vivo antibiotic efficacy against a novel bioluminescent Shigella flexneri

por McCloskey, Molly C., Shaheen, Shareef, Rabago, Lesley, Hulverson, Matthew A., Choi, Ryan, Barrett, Lynn K., Arnold, Samuel L. M.
Publicado 2019

Author Correction: Evaluation of in vitro and in vivo antibiotic efficacy against a novel bioluminescent Shigella flexneri

por McCloskey, Molly C., Shaheen, Shareef, Rabago, Lesley, Hulverson, Matthew A., Choi, Ryan, Barrett, Lynn K., Arnold, Samuel L. M.
Publicado 2020

Structure of thymidylate kinase from Ehrlichia chaffeensis

por Leibly, David J., Abendroth, Jan, Bryan, Cassie M., Sankaran, Banumathi, Kelley, Angela, Barrett, Lynn K., Stewart, Lance, Van Voorhis, Wesley C.
Publicado 2011

Screening of the Pathogen Box for inhibitors with dual efficacy against Giardia lamblia and Cryptosporidium parvum

por Hennessey, Kelly M., Rogiers, Ilse C., Shih, Han-Wei, Hulverson, Matthew A., Choi, Ryan, McCloskey, Molly C., Whitman, Grant R., Barrett, Lynn K., Merritt, Ethan A., Paredez, Alexander R., Ojo, Kayode K.
Publicado 2018

Conducting clinical trials in sub-Saharan Africa: challenges and lessons learned from the Malawi Cryptosporidium study

por Toto, Neema, Douglas, Elaine, Gmeiner, Markus, Barrett, Lynn K., Lindblad, Robert, Makhaza, Lumbani, Nedi, Wilfred, Phulusa, Jacob, Quinnan, Gerald V., Sawyer, Leigh A., Thole, Herbert, Van Voorhis, Wesley C., Iroh Tam, Pui-Ying
Publicado 2020

Recombinant human G6PD for quality control and quality assurance of novel point-of-care diagnostics for G6PD deficiency

por Kahn, Maria, LaRue, Nicole, Zhu, Changcheng, Pal, Sampa, Mo, Jack S., Barrett, Lynn K., Hewitt, Steve N., Dumais, Mitchell, Hemmington, Sandra, Walker, Adrian, Joynson, Jeff, Leader, Brandon T., Van Voorhis, Wesley C., Domingo, Gonzalo J.
Publicado 2017

P-Glycoprotein–Mediated Efflux Reduces the In Vivo Efficacy of a Therapeutic Targeting the Gastrointestinal Parasite Cryptosporidium

por Arnold, Samuel L M, Choi, Ryan, Hulverson, Matthew A, Whitman, Grant R, Mccloskey, Molly C, Dorr, Carlie S, Vidadala, Rama S R, Khatod, Mansi, Morada, Mary, Barrett, Lynn K, Maly, Dustin J, Yarlett, Nigel, Van Voorhis, Wesley C
Publicado 2019

The transcriptome of Balamuthia mandrillaris trophozoites for structure-guided drug design

por Phan, Isabelle Q., Rice, Christopher A., Craig, Justin, Noorai, Rooksana E., McDonald, Jacquelyn R., Subramanian, Sandhya, Tillery, Logan, Barrett, Lynn K., Shankar, Vijay, Morris, James C., Van Voorhis, Wesley C., Kyle, Dennis E., Myler, Peter J.
Publicado 2021

Detection of SARS-CoV-2 in Terrestrial Animals in Southern Nigeria: Potential Cases of Reverse Zoonosis

por Happi, Anise N., Ayinla, Akeemat O., Ogunsanya, Olusola A., Sijuwola, Ayotunde E., Saibu, Femi M., Akano, Kazeem, George, Uwem E., Sopeju, Adebayo E., Rabinowitz, Peter M., Ojo, Kayode K., Barrett, Lynn K., Van Voorhis, Wesley C., Happi, Christian T.
Publicado 2023

Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis

por Ojo, Kayode K., Ranade, Ranae M., Zhang, Zhongsheng, Dranow, David M., Myers, Janette B., Choi, Ryan, Nakazawa Hewitt, Steve, Edwards, Thomas E., Davies, Douglas R., Lorimer, Donald, Boyle, Stephen M., Barrett, Lynn K., Buckner, Frederick S., Fan, Erkang, Van Voorhis, Wesley C.
Publicado 2016

Correction: Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis

por Ojo, Kayode K., Ranade, Ranae M., Zhang, Zhongsheng, Dranow, David M., Myers, Janette B., Choi, Ryan, Nakazawa Hewitt, Steve, Edwards, Thomas E., Davies, Douglas R., Lorimer, Donald, Boyle, Stephen M., Barrett, Lynn K., Buckner, Frederick S., Fan, Erkang, Van Voorhis, Wesley C.
Publicado 2016

Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium Infection

por Arnold, Samuel L. M., Choi, Ryan, Hulverson, Matthew A., Schaefer, Deborah A., Vinayak, Sumiti, Vidadala, Rama S. R., McCloskey, Molly C., Whitman, Grant R., Huang, Wenlin, Barrett, Lynn K., Ojo, Kayode K., Fan, Erkang, Maly, Dustin J., Riggs, Michael W., Striepen, Boris, Van Voorhis, Wesley C.
Publicado 2017

Bumped kinase inhibitor 1369 is effective against Cystoisospora suis in vivo and in vitro

por Shrestha, Aruna, Ojo, Kayode K., Koston, Florian, Ruttkowski, Bärbel, Vidadala, Rama S.R., Dorr, Carlie S., Navaluna, Edelmar D., Whitman, Grant R., Barrett, Kayleigh F., Barrett, Lynn K., Hulverson, Matthew A., Choi, Ryan, Michaels, Samantha A., Maly, Dustin J., Hemphill, Andrew, Van Voorhis, Wesley C., Joachim, Anja
Publicado 2019

High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV-2 nsp15 endoribonuclease to identify small-molecule inhibitors of...

por Choi, Ryan, Zhou, Mowei, Shek, Roger, Wilson, Jesse W., Tillery, Logan, Craig, Justin K., Salukhe, Indraneel A., Hickson, Sarah E., Kumar, Neeraj, James, Rhema M., Buchko, Garry W., Wu, Ruilian, Huff, Sydney, Nguyen, Tu-Trinh, Hurst, Brett L., Cherry, Sara, Barrett, Lynn K., Hyde, Jennifer L., Van Voorhis, Wesley C.
Publicado 2021

In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19

por Phan, Isabelle Q., Subramanian, Sandhya, Kim, David, Murphy, Michael, Pettie, Deleah, Carter, Lauren, Anishchenko, Ivan, Barrett, Lynn K., Craig, Justin, Tillery, Logan, Shek, Roger, Harrington, Whitney E., Koelle, David M., Wald, Anna, Veesler, David, King, Neil, Boonyaratanakornkit, Jim, Isoherranen, Nina, Greninger, Alexander L., Jerome, Keith R., Chu, Helen, Staker, Bart, Stewart, Lance, Myler, Peter J., Van Voorhis, Wesley C.
Publicado 2021

Shotgun Kinetic Target-Guided Synthesis Approach Enables the Discovery of Small-Molecule Inhibitors against Pathogenic Free-Living Amoeba Glucokinases

por Kassu, Mintesinot, Parvatkar, Prakash T., Milanes, Jillian, Monaghan, Neil P., Kim, Chungsik, Dowgiallo, Matthew, Zhao, Yingzhao, Asakawa, Ami H., Huang, Lili, Wagner, Alicia, Miller, Brandon, Carter, Karissa, Barrett, Kayleigh F., Tillery, Logan M., Barrett, Lynn K., Phan, Isabelle Q., Subramanian, Sandhya, Myler, Peter J., Van Voorhis, Wesley C., Leahy, James W., Rice, Christopher A., Kyle, Dennis E., Morris, James, Manetsch, Roman
Publicado 2023

Safety and efficacy of the bumped kinase inhibitor BKI-1553 in pregnant sheep experimentally infected with Neospora caninum tachyzoites

por Sánchez-Sánchez, Roberto, Ferre, Ignacio, Re, Michela, Vázquez, Patricia, Ferrer, Luis Miguel, Blanco-Murcia, Javier, Regidor-Cerrillo, Javier, Pizarro Díaz, Manuel, González-Huecas, Marta, Tabanera, Enrique, García-Lunar, Paula, Benavides, Julio, Castaño, Pablo, Hemphill, Andrew, Hulverson, Matthew A., Whitman, Grant R., Rivas, Kasey L., Choi, Ryan, Ojo, Kayode K., Barrett, Lynn K., Van Voorhis, Wesley C., Ortega-Mora, Luis Miguel
Publicado 2018

Dynamics of SARS-CoV-2 VOC Neutralization and Novel mAb Reveal Protection against Omicron

por Hao, Linhui, Hsiang, Tien-Ying, Dalmat, Ronit R., Ireton, Renee, Morton, Jennifer F., Stokes, Caleb, Netland, Jason, Hale, Malika, Thouvenel, Chris, Wald, Anna, Franko, Nicholas M., Huden, Kristen, Chu, Helen Y., Sigal, Alex, Greninger, Alex L., Tilles, Sasha, Barrett, Lynn K., Van Voorhis, Wesley C., Munt, Jennifer, Scobey, Trevor, Baric, Ralph S., Rawlings, David J., Pepper, Marion, Drain, Paul K., Gale, Michael
Publicado 2023

Comparison of Toxicities among Different Bumped Kinase Inhibitor Analogs for Treatment of Cryptosporidiosis

por Hulverson, Matthew A., Choi, Ryan, Schaefer, Deborah A., Betzer, Dana P., McCloskey, Molly C., Whitman, Grant R., Huang, Wenlin, Lee, Sangun, Pranata, Andy, McLeod, Malcolm D., Marsh, Kennan C., Kempf, Dale J., LeRoy, Bruce E., Zafiratos, Mark T., Bielinski, Aimee L., Hackman, Robert C., Ojo, Kayode K., Arnold, Samuel L. M., Barrett, Lynn K., Tzipori, Saul, Riggs, Michael W., Fan, Erkang, Van Voorhis, Wesley C.
Publicado 2023