Exploration of expanded carbohydrate chemical space to access biological activity using microwave-induced acid condensation of simple sugars

por London, James Andrew, Taylor, Sarah Louise, Barsukov, Igor, Cartmell, Alan, Yates, Edwin Alexander
Publicado 2022

Relief of talin autoinhibition triggers a force-independent association with vinculin

por Atherton, Paul, Lausecker, Franziska, Carisey, Alexandre, Gilmore, Andrew, Critchley, David, Barsukov, Igor, Ballestrem, Christoph
Publicado 2019

Direct interaction of metastasis-inducing S100P protein with tubulin causes enhanced cell migration without changes in cell adhesion

por Du, Min, Wang, Guozheng, Barsukov, Igor L., Gross, Stephane R., Smith, Richard, Rudland, Philip S.
Publicado 2020

Domain Motion in Cytochrome P450 Reductase: CONFORMATIONAL EQUILIBRIA REVEALED BY NMR AND SMALL-ANGLE X-RAY SCATTERING

por Ellis, Jacqueline, Gutierrez, Aldo, Barsukov, Igor L., Huang, Wei-Cheng, Grossmann, J. Günter, Roberts, Gordon C. K.
Publicado 2009

The domain structure of talin: Residues 1815–1973 form a five-helix bundle containing a cryptic vinculin-binding site

por Goult, Benjamin T., Gingras, Alexandre R., Bate, Neil, Barsukov, Igor L., Critchley, David R., Roberts, Gordon C.K.
Publicado 2010

LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex

por Zacharchenko, Thomas, Qian, Xiaolan, Goult, Benjamin T., Jethwa, Devina, Almeida, Teresa B., Ballestrem, Christoph, Critchley, David R., Lowy, Douglas R., Barsukov, Igor L.
Publicado 2016

The Structure of the Talin Head Reveals a Novel Extended Conformation of the FERM Domain

por Elliott, Paul R., Goult, Benjamin T., Kopp, Petra M., Bate, Neil, Grossmann, J. Günter, Roberts, Gordon C.K., Critchley, David R., Barsukov, Igor L.
Publicado 2010

Anion binding to a cationic europium(iii) probe enables the first real-time assay of heparan sulfotransferase activity

por Wheeler, Simon, Breen, Colum, Li, Yong, Hewitt, Sarah H., Robertson, Erin, Yates, Edwin A., Barsukov, Igor L., Fernig, David G., Butler, Stephen J.
Publicado 2021

Central Region of Talin Has a Unique Fold That Binds Vinculin and Actin

por Gingras, Alexandre R., Bate, Neil, Goult, Benjamin T., Patel, Bipin, Kopp, Petra M., Emsley, Jonas, Barsukov, Igor L., Roberts, Gordon C. K., Critchley, David R.
Publicado 2010

Tensin3 interaction with talin drives the formation of fibronectin-associated fibrillar adhesions

por Atherton, Paul, Konstantinou, Rafaella, Neo, Suat Peng, Wang, Emily, Balloi, Eleonora, Ptushkina, Marina, Bennett, Hayley, Clark, Kath, Gunaratne, Jayantha, Critchley, David, Barsukov, Igor, Manser, Edward, Ballestrem, Christoph
Publicado 2022

The Structure of an Interdomain Complex That Regulates Talin Activity

por Goult, Benjamin T., Bate, Neil, Anthis, Nicholas J., Wegener, Kate L., Gingras, Alexandre R., Patel, Bipin, Barsukov, Igor L., Campbell, Iain D., Roberts, Gordon C. K., Critchley, David R.
Publicado 2009

The Structure of the N-Terminus of Kindlin-1: A Domain Important for αIIbβ3 Integrin Activation

por Goult, Benjamin T., Bouaouina, Mohamed, Harburger, David S., Bate, Neil, Patel, Bipin, Anthis, Nicholas J., Campbell, Iain D., Calderwood, David A., Barsukov, Igor L., Roberts, Gordon C., Critchley, David R.
Publicado 2009

RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover

por Goult, Benjamin T., Zacharchenko, Thomas, Bate, Neil, Tsang, Ricky, Hey, Fiona, Gingras, Alexandre R., Elliott, Paul R., Roberts, Gordon C. K., Ballestrem, Christoph, Critchley, David R., Barsukov, Igor L.
Publicado 2013

Mutations affecting the N-terminal domains of SHANK3 point to different pathomechanisms in neurodevelopmental disorders

por Woike, Daniel, Wang, Emily, Tibbe, Debora, Hassani Nia, Fatemeh, Failla, Antonio Virgilio, Kibæk, Maria, Overgård, Tinett Martesen, Larsen, Martin J., Fagerberg, Christina R., Barsukov, Igor, Kreienkamp, Hans-Jürgen
Publicado 2022

Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation

por Goult, Benjamin T, Bouaouina, Mohamed, Elliott, Paul R, Bate, Neil, Patel, Bipin, Gingras, Alexandre R, Grossmann, J Günter, Roberts, Gordon C K, Calderwood, David A, Critchley, David R, Barsukov, Igor L
Publicado 2010

Vinculin controls talin engagement with the actomyosin machinery

por Atherton, Paul, Stutchbury, Ben, Wang, De-Yao, Jethwa, Devina, Tsang, Ricky, Meiler-Rodriguez, Eugenia, Wang, Pengbo, Bate, Neil, Zent, Roy, Barsukov, Igor L., Goult, Benjamin T., Critchley, David R., Ballestrem, Christoph
Publicado 2015

Mechanism of the Ca(2+)-Dependent Interaction between S100A4 and Tail Fragments of Nonmuscle Myosin Heavy Chain IIA

por Badyal, Sandip K., Basran, Jaswir, Bhanji, Nina, Kim, Ju Hwan, Chavda, Alap P., Jung, Hyun Suk, Craig, Roger, Elliott, Paul R., Irvine, Andrew F., Barsukov, Igor L., Kriajevska, Marina, Bagshaw, Clive R.
Publicado 2011

The structure of the C-terminal actin-binding domain of talin

por Gingras, Alexandre R, Bate, Neil, Goult, Benjamin T, Hazelwood, Larnele, Canestrelli, Ilona, Grossmann, J Günter, Liu, HongJun, Putz, Nicholas S M, Roberts, Gordon C K, Volkmann, Niels, Hanein, Dorit, Barsukov, Igor L, Critchley, David R
Publicado 2008

SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras

por Lilja, Johanna, Zacharchenko, Thomas, Georgiadou, Maria, Jacquemet, Guillaume, De Franceschi, Nicola, Peuhu, Emilia, Hamidi, Hellyeh, Pouwels, Jeroen, Martens, Victoria, Nia, Fatemeh Hassani, Beifuss, Malte, Boeckers, Tobias, Kreienkamp, Hans-Juergen, Barsukov, Igor L, Ivaska, Johanna
Publicado 2017

Asymmetric Mode of Ca(2+)-S100A4 Interaction with Nonmuscle Myosin IIA Generates Nanomolar Affinity Required for Filament Remodeling

por Elliott, Paul R., Irvine, Andrew F., Jung, Hyun Suk, Tozawa, Kaeko, Pastok, Martyna W., Picone, Remigio, Badyal, Sandip K., Basran, Jaswir, Rudland, Philip S., Barraclough, Roger, Lian, Lu-Yun, Bagshaw, Clive R., Kriajevska, Marina, Barsukov, Igor L.
Publicado 2012