Genome mining of biosynthetic and chemotherapeutic gene clusters in Streptomyces bacteria

por Belknap, Kaitlyn C., Park, Cooper J., Barth, Brian M., Andam, Cheryl P.
Publicado 2020

Engraftment of Human Primary Acute Myeloid Leukemia Defined by Integrated Genetic Profiling in NOD/SCID/IL2rγnull Mice for Preclinical Ceramide-Based Therapeutic Evaluation

por Barth, Brian M, Keasey, Nichole R, Wang, Xujung, Shanmugavelandy, Sriram S, Rampal, Raajit, Hricik, Todd, Cabot, Myles C, Kester, Mark, Wang, Hong-Gang, Shultz, Leonard D, Tallman, Martin S, Levine, Ross L, Loughran, Thomas P, Claxton, David F
Publicado 2014

Acute myeloid leukemia stratifies as two clinically relevant sphingolipidomic subtypes

por Paudel, B. Bishal, Tan, Su-Fern, Fox, Todd E., Ung, Johnson, Shaw, Jeremy, Dunton, Wendy, Lee, Irene, Sharma, Arati, Viny, Aaron D., Barth, Brian M., Tallman, Martin S., Cabot, Myles, Garrett-Bakelman, Francine E., Levine, Ross L., Kester, Mark, Claxton, David, Feith, David J., Janes, Kevin A., Loughran, Thomas P.
Publicado 2023

The Pleiotropic Actions of Adiponectin are Initiated via Receptor-Mediated Activation of Ceramidase Activity

por Holland, William L., Miller, Russell A., Wang, Zhao V., Sun, Kai, Barth, Brian M., Bui, Hai H., Davis, Kathryn E., Bikman, Benjamin T., Halberg, Nils, Rutkowski, Joseph M., Wade, Mark R., Tenorio, Vincent M., Kuo, Ming-Shang, Brozinick, Joseph T., Zhang, Bei B., Birnbaum, Morris J., Summers, Scott A., Scherer, Philipp E.
Publicado 2010

Acid ceramidase is upregulated in AML and represents a novel therapeutic target

por Tan, Su-Fern, Liu, Xin, Fox, Todd E., Barth, Brian M., Sharma, Arati, Turner, Stephen D., Awwad, Andy, Dewey, Alden, Doi, Kenichiro, Spitzer, Barbara, Shah, Mithun Vinod, Morad, Samy A.F., Desai, Dhimant, Amin, Shantu, Zhu, Junjia, Liao, Jason, Yun, Jong, Kester, Mark, Claxton, David F., Wang, Hong-Gang, Cabot, Myles C., Schuchman, Edward H., Levine, Ross L., Feith, David J., Loughran, Thomas P.
Publicado 2016