DRAM‐4 and DRAM‐5 are compensatory regulators of autophagy and cell survival in nutrient‐deprived conditions

por Barthet, Valentin J. A., Mrschtik, Michaela, Kania, Elzbieta, McEwan, David G., Croft, Dan, O'Prey, James, Long, Jaclyn S., Ryan, Kevin M.
Publicado 2022

ATG7 is a haploinsufficient repressor of tumor progression and promoter of metastasis

por Long, Jaclyn S., Kania, Elżbieta, McEwan, David G., Barthet, Valentin J. A., Brucoli, Martina, Ladds, Marcus J.G.W., Nössing, Christoph, Ryan, Kevin M.
Publicado 2022

Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

por Barthet, Valentin J. A., Brucoli, Martina, Ladds, Marcus J. G. W., Nössing, Christoph, Kiourtis, Christos, Baudot, Alice D., O’Prey, James, Zunino, Barbara, Müller, Miryam, May, Stephanie, Nixon, Colin, Long, Jaclyn S., Bird, Thomas G., Ryan, Kevin M.
Publicado 2021

mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux

por Beaumatin, Florian, O’Prey, Jim, Barthet, Valentin J.A., Zunino, Barbara, Parvy, Jean-Philippe, Bachmann, Alexis Maximilien, O’Prey, Margaret, Kania, Elżbieta, Gonzalez, Pablo Sierra, Macintosh, Robin, Lao, Laurence Y., Nixon, Colin, Lopez, Jonathan, Long, Jaclyn S., Tait, Stephen W.G., Ryan, Kevin M.
Publicado 2019

Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction

por Amor, Corina, Fernández-Maestre, Inés, Chowdhury, Saria, Ho, Yu-Jui, Nadella, Sandeep, Graham, Courtenay, Carrasco, Sebastian E., Nnuji-John, Emmanuella, Feucht, Judith, Hinterleitner, Clemens, Barthet, Valentin J.A., Boyer, Jacob A., Mezzadra, Riccardo, Wereski, Matthew G, Tuveson, David A., Levine, Ross L., Jones, Lee W, Sadelain, Michel, Lowe, Scott W
Publicado 2023