Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity predictions o...

por MacGowan, Stuart A., Barton, Michael I., Kutuzov, Mikhail, Dushek, Omer, van der Merwe, P. Anton, Barton, Geoffrey J.
Publicado 2022

Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics

por Barton, Michael I, MacGowan, Stuart A, Kutuzov, Mikhail A, Dushek, Omer, Barton, Geoffrey John, van der Merwe, P Anton
Publicado 2021

A generic cell surface ligand system for studying cell–cell recognition

por Denham, Eleanor M., Barton, Michael I., Black, Susannah M., Bridge, Marcus J., de Wet, Ben, Paterson, Rachel L., van der Merwe, P. Anton, Goyette, Jesse
Publicado 2019