Novel machine learning models to predict endocrine disruption activity for high-throughput chemical screening

por Collins, Sean P., Barton-Maclaren, Tara S.
Publicado 2022

Canadian Regulatory Perspective on Next Generation Risk Assessments for Pest Control Products and Industrial Chemicals

por Bhuller, Yadvinder, Ramsingh, Deborah, Beal, Marc, Kulkarni, Sunil, Gagne, Matthew, Barton-Maclaren, Tara S
Publicado 2021

Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo mutageni...

por Chepelev, Nikolai, Long, Alexandra S., Beal, Marc, Barton‐Maclaren, Tara, Johnson, George, Dearfield, Kerry L., Roberts, Daniel J., van Benthem, Jan, White, Paul
Publicado 2023

Comprehensive interpretation of in vitro micronucleus test results for 292 chemicals: from hazard identification to risk assessment application

por Kuo, Byron, Beal, Marc A., Wills, John W., White, Paul A., Marchetti, Francesco, Nong, Andy, Barton-Maclaren, Tara S., Houck, Keith, Yauk, Carole L.
Publicado 2022

Recommended approaches in the application of toxicogenomics to derive points of departure for chemical risk assessment

por Farmahin, Reza, Williams, Andrew, Kuo, Byron, Chepelev, Nikolai L., Thomas, Russell S., Barton-Maclaren, Tara S., Curran, Ivan H., Nong, Andy, Wade, Michael G., Yauk, Carole L.
Publicado 2016

Use of new approach methodologies (NAMs) to meet regulatory requirements for the assessment of industrial chemicals and pesticides for effects on human health

por Stucki, Andreas O., Barton-Maclaren, Tara S., Bhuller, Yadvinder, Henriquez, Joseph E., Henry, Tala R., Hirn, Carole, Miller-Holt, Jacqueline, Nagy, Edith G., Perron, Monique M., Ratzlaff, Deborah E., Stedeford, Todd J., Clippinger, Amy J.
Publicado 2022

In vitro transcriptomic analyses reveal pathway perturbations, estrogenic activities, and potencies of data-poor BPA alternative chemicals

por Matteo, Geronimo, Leingartner, Karen, Rowan-Carroll, Andrea, Meier, Matthew, Williams, Andrew, Beal, Marc A, Gagné, Matthew, Farmahin, Reza, Wickramasuriya, Shamika, Reardon, Anthony J F, Barton-Maclaren, Tara, Christopher Corton, J, Yauk, Carole L, Atlas, Ella
Publicado 2022

From vision toward best practices: Evaluating in vitro transcriptomic points of departure for application in risk assessment using a uniform workflow

por Reardon, Anthony J. F., Farmahin, Reza, Williams, Andrew, Meier, Matthew J., Addicks, Gregory C., Yauk, Carole L., Matteo, Geronimo, Atlas, Ella, Harrill, Joshua, Everett, Logan J., Shah, Imran, Judson, Richard, Ramaiahgari, Sreenivasa, Ferguson, Stephen S., Barton-Maclaren, Tara S.
Publicado 2023

A Transformative Vision for an Omics-Based Regulatory Chemical Testing Paradigm

por Johnson, Kamin J, Auerbach, Scott S, Stevens, Tina, Barton-Maclaren, Tara S, Costa, Eduardo, Currie, Richard A, Dalmas Wilk, Deidre, Haq, Saddef, Rager, Julia E, Reardon, Anthony J F, Wehmas, Leah, Williams, Andrew, O’Brien, Jason, Yauk, Carole, LaRocca, Jessica L, Pettit, Syril
Publicado 2022

Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients

por Dent, M.P., Vaillancourt, E., Thomas, R.S., Carmichael, P.L., Ouedraogo, G., Kojima, H., Barroso, J., Ansell, J., Barton-Maclaren, T.S., Bennekou, S.H., Boekelheide, K., Ezendam, J., Field, J., Fitzpatrick, S., Hatao, M., Kreiling, R., Lorencini, M., Mahony, C., Montemayor, B., Mazaro-Costa, R., Oliveira, J., Rogiers, V., Smegal, D., Taalman, R., Tokura, Y., Verma, R., Willett, C., Yang, C.
Publicado 2021

Internationalization of Read-Across as a Validated New Approach Method (NAM) for Regulatory Toxicology

por Rovida, Costanza, Barton-Maclaren, Tara, Benfenati, Emilio, Caloni, Francesca, Chandrasekera, P. Charukeshi, Chesné, Christophe, Cronin, Mark T. D., De Knecht, Joop, Dietrich, Daniel R., Escher, Sylvia E., Fitzpatrick, Suzanne, Flannery, Brenna, Herzler, Matthias, Bennekou, Susanne Hougaard, Hubesch, Bruno, Kamp, Hennicke, Kisitu, Jaffar, Kleinstreuer, Nicole, Kovarich, Simona, Leist, Marcel, Maertens, Alexandra, Nugent, Kerry, Pallocca, Giorgia, Pastor, Manuel, Patlewicz, Grace, Pavan, Manuela, Presgrave, Octavio, Smirnova, Lena, Schwarz, Michael, Yamada, Takashi, Hartung, Thomas
Publicado 2020