Extracellular loops 1 and 3 and their associated transmembrane regions of the calcitonin receptor-like receptor are needed for CGRP receptor function

por Barwell, James, Conner, Alex, Poyner, David R.
Publicado 2011

Mapping interaction sites within the N-terminus of the calcitonin gene-related peptide receptor; the role of residues 23–60 of the calcitonin receptor-like receptor

por Barwell, James, Miller, Philip S., Donnelly, Dan, Poyner, David R.
Publicado 2010

Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74

por Miller, Philip S., Barwell, James, Poyner, David R., Wigglesworth, Mark J., Garland, Stephen L., Donnelly, Dan
Publicado 2010

Structure–activity relationships of the N-terminus of calcitonin gene-related peptide: key roles of alanine-5 and threonine-6 in receptor activation

por Hay, Debbie L, Harris, Paul WR, Kowalczyk, Renata, Brimble, Margaret A, Rathbone, Dan L, Barwell, James, Conner, Alex C, Poyner, David R
Publicado 2014

An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology

por J Gingell, Joseph, Simms, John, Barwell, James, Poyner, David R, Watkins, Harriet A, Pioszak, Augen A, Sexton, Patrick M, Hay, Debbie L
Publicado 2016

An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology

por Gingell, Joseph J, Simms, John, Barwell, James, Poyner, David R, Watkins, Harriet A, Pioszak, Augen A, Sexton, Patrick M, Hay, Debbie L
Publicado 2016

Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies

por Vohra, Shabana, Taddese, Bruck, Conner, Alex C., Poyner, David R., Hay, Debbie L., Barwell, James, Reeves, Philip J., Upton, Graham J. G., Reynolds, Christopher A.
Publicado 2013

The role of ECL2 in CGRP receptor activation: a combined modelling and experimental approach

por Woolley, Michael. J., Watkins, Harriet A., Taddese, Bruck, Karakullukcu, Z. Gamze, Barwell, James, Smith, Kevin J., Hay, Debbie L., Poyner, David R., Reynolds, Christopher A., Conner, Alex C.
Publicado 2013

Production, Purification and Characterization of Recombinant, Full-Length Human Claudin-1

por Bonander, Nicklas, Jamshad, Mohammed, Oberthür, Dominik, Clare, Michelle, Barwell, James, Hu, Ke, Farquhar, Michelle J., Stamataki, Zania, Harris, Helen J., Dierks, Karsten, Dafforn, Timothy R., Betzel, Christian, McKeating, Jane A., Bill, Roslyn M.
Publicado 2013

Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor

por Booe, Jason M., Walker, Christopher S., Barwell, James, Kuteyi, Gabriel, Simms, John, Jamaluddin, Muhammad A., Warner, Margaret L., Bill, Roslyn M., Harris, Paul W., Brimble, Margaret A., Poyner, David R., Hay, Debbie L., Pioszak, Augen A.
Publicado 2015

Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties

por Watkins, Harriet A., Chakravarthy, Madhuri, Abhayawardana, Rekhati S., Gingell, Joseph J., Garelja, Michael, Pardamwar, Meenakshi, McElhinney, James M. W. R., Lathbridge, Alex, Constantine, Arran, Harris, Paul W. R., Yuen, Tsz-Ying, Brimble, Margaret A., Barwell, James, Poyner, David R., Woolley, Michael J., Conner, Alex C., Pioszak, Augen A., Reynolds, Christopher A., Hay, Debbie L.
Publicado 2016