Cell of Origin and Genetic Alterations in the Pathogenesis of Multiple Myeloma

por Barwick, Benjamin G., Gupta, Vikas A., Vertino, Paula M., Boise, Lawrence H.
Publicado 2019

Plasma cell differentiation is coupled to division-dependent DNA hypomethylation and gene regulation

por Barwick, Benjamin G., Scharer, Christopher D., Bally, Alexander P.R., Boss, Jeremy M.
Publicado 2016

Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs

por Scharer, Christopher D., Barwick, Benjamin G., Guo, Muyao, Bally, Alexander P. R., Boss, Jeremy M.
Publicado 2018

Whole‐genome analysis of TET dioxygenase function in regulatory T cells

por Yue, Xiaojing, Samaniego‐Castruita, Daniela, González‐Avalos, Edahí, Li, Xiang, Barwick, Benjamin G, Rao, Anjana
Publicado 2021

Genome-wide CIITA-binding profile identifies sequence preferences that dictate function versus recruitment

por Scharer, Christopher D., Choi, Nancy M., Barwick, Benjamin G., Majumder, Parimal, Lohsen, Sarah, Boss, Jeremy M.
Publicado 2015

ATAC-seq on biobanked specimens defines a unique chromatin accessibility structure in naïve SLE B cells

por Scharer, Christopher D., Blalock, Emily L., Barwick, Benjamin G., Haines, Robert R., Wei, Chungwen, Sanz, Ignacio, Boss, Jeremy M.
Publicado 2016

MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma

por Wang, Dongxue, Hashimoto, Hideharu, Zhang, Xing, Barwick, Benjamin G., Lonial, Sagar, Boise, Lawrence H., Vertino, Paula M., Cheng, Xiaodong
Publicado 2017

Common distal elements orchestrate CIITA isoform-specific expression in multiple cell types

por Lohsen, Sarah, Majumder, Parimal, Scharer, Christopher D., Barwick, Benjamin G., Austin, James W., Zinzow-Kramer, Wendy M., Boss, Jeremy M.
Publicado 2014

Downregulation of PA28α induces proteasome remodeling and results in resistance to proteasome inhibitors in multiple myeloma

por Gu, Yanyan, Barwick, Benjamin G., Shanmugam, Mala, Hofmeister, Craig C., Kaufman, Jonathan, Nooka, Ajay, Gupta, Vikas, Dhodapkar, Madhav, Boise, Lawrence H., Lonial, Sagar
Publicado 2020

Heterozygosity for Pten Promotes Tumorigenesis in a Mouse Model of Medulloblastoma

por Castellino, Robert C., Barwick, Benjamin G., Schniederjan, Matthew, Buss, Meghan C., Becher, Oren, Hambardzumyan, Dolores, MacDonald, Tobey J., Brat, Daniel J., Durden, Donald L.
Publicado 2010

β adrenergic signaling regulates hematopoietic stem and progenitor cell commitment and therapy sensitivity in multiple myeloma

por Nair, Remya, Subramaniam, Vimal, Barwick, Benjamin G., Gupta, Vikas A., Matulis, Shannon M., Lonial, Sagar, Boise, Lawrence H., Nooka, Ajay K., Muthumalaiappan, Kuzhali, Shanmugam, Mala
Publicado 2022

A heterozygous IDH1(R132H/WT) mutation induces genome-wide alterations in DNA methylation

por Duncan, Christopher G., Barwick, Benjamin G., Jin, Genglin, Rago, Carlo, Kapoor-Vazirani, Priya, Powell, Doris R., Chi, Jen-Tsan, Bigner, Darell D., Vertino, Paula M., Yan, Hai
Publicado 2012

LSD1 protects against hippocampal and cortical neurodegeneration

por Christopher, Michael A., Myrick, Dexter A., Barwick, Benjamin G., Engstrom, Amanda K., Porter-Stransky, Kirsten A., Boss, Jeremy M., Weinshenker, David, Levey, Allan I., Katz, David J.
Publicado 2017

B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation

por Barwick, Benjamin G., Scharer, Christopher D., Martinez, Ryan J., Price, Madeline J., Wein, Alexander N., Haines, Robert R., Bally, Alexander P. R., Kohlmeier, Jacob E., Boss, Jeremy M.
Publicado 2018

Wnt signaling in triple negative breast cancer is associated with metastasis

por Dey, Nandini, Barwick, Benjamin G, Moreno, Carlos S, Ordanic-Kodani, Maja, Chen, Zhengjia, Oprea-Ilies, Gabriella, Tang, Weining, Catzavelos, Charles, Kerstann, Kimberly F, Sledge, George W, Abramovitz, Mark, Bouzyk, Mark, De, Pradip, Leyland-Jones, Brian R
Publicado 2013

Multivariant Transcriptome Analysis Identifies Modules and Hub Genes Associated with Poor Outcomes in Newly Diagnosed Multiple Myeloma Patients

por Adebayo, Olayinka O., Dammer, Eric B., Dill, Courtney D., Adebayo, Adeyinka O., Oseni, Saheed O., Griffen, Ti’ara L., Ohandjo, Adaugo Q., Yan, Fengxia, Jain, Sanjay, Barwick, Benjamin G., Singh, Rajesh, Boise, Lawrence H., Lillard, Jr., James W.
Publicado 2022

Multiple myeloma immunoglobulin lambda translocations portend poor prognosis

por Barwick, Benjamin G., Neri, Paola, Bahlis, Nizar J., Nooka, Ajay K., Dhodapkar, Madhav V., Jaye, David L., Hofmeister, Craig C., Kaufman, Jonathan L., Gupta, Vikas A., Auclair, Daniel, Keats, Jonathan J., Lonial, Sagar, Vertino, Paula M., Boise, Lawrence H.
Publicado 2019

Epigenetically heterogeneous tumor cells direct collective invasion through filopodia-driven fibronectin micropatterning

por Summerbell, Emily R., Mouw, Janna K., Bell, Joshua S. K., Knippler, Christina M., Pedro, Brian, Arnst, Jamie L., Khatib, Tala O., Commander, Rachel, Barwick, Benjamin G., Konen, Jessica, Dwivedi, Bhakti, Seby, Sandra, Kowalski, Jeanne, Vertino, Paula M., Marcus, Adam I.
Publicado 2020

Epigenetic programming underpins B cell dysfunction in human SLE

por Scharer, Christopher D., Blalock, Emily L., Mi, Tian, Barwick, Benjamin G., Jenks, Scott A., Deguchi, Tsuneo, Cashman, Kevin S., Neary, Bridget E., Patterson, Dillon G., Hicks, Sakeenah L., Khosroshahi, Arezou, Lee, F. Eun-Hyung, Wei, Chungwen, Sanz, Iñaki, Boss, Jeremy M.
Publicado 2019

Gain of Chromosome 1q is associated with early progression in multiple myeloma patients treated with lenalidomide, bortezomib, and dexamethasone

por Schmidt, Timothy M., Barwick, Benjamin G., Joseph, Nisha, Heffner, Leonard T., Hofmeister, Craig C., Bernal, Leon, Dhodapkar, Madhav V., Gupta, Vikas A., Jaye, David L., Wu, Jiayi, Goyal, Subir, Chen, Zhengjia, Boise, Lawrence H., Lonial, Sagar, Nooka, Ajay K., Kaufman, Jonathan L.
Publicado 2019