Amyloid β Modification: A Key to the Sporadic Alzheimer's Disease?

por Barykin, Evgeny P., Mitkevich, Vladimir A., Kozin, Sergey A., Makarov, Alexander A.
Publicado 2017

Synthetic, Cell-Derived, Brain-Derived, and Recombinant β-Amyloid: Modelling Alzheimer’s Disease for Research and Drug Development

por Varshavskaya, Kseniya B., Mitkevich, Vladimir A., Makarov, Alexander A., Barykin, Evgeny P.
Publicado 2022

Phosphorylation and Dephosphorylation of Beta-Amyloid Peptide in Model Cell Cultures: The Role of Cellular Protein Kinases and Phosphatases

por Barykin, Evgeny P., Yanvarev, Dmitry V., Strelkova, Maria A., Valuev-Elliston, Vladimir T., Varshavskaya, Kseniya B., Mitkevich, Vladimir A., Makarov, Alexander A.
Publicado 2023

Intravenously Injected Amyloid-β Peptide With Isomerized Asp7 and Phosphorylated Ser8 Residues Inhibits Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice Model of Alzheimer’s Dise...

por Kozin, Sergey A., Barykin, Evgeny P., Telegin, Georgy B., Chernov, Alexander S., Adzhubei, Alexei A., Radko, Sergey P., Mitkevich, Vladimir A., Makarov, Alexander A.
Publicado 2018

Distinct Effects of Beta-Amyloid, Its Isomerized and Phosphorylated Forms on the Redox Status and Mitochondrial Functioning of the Blood–Brain Barrier Endothelium

por Petrovskaya, Aleksandra V., Tverskoi, Artem M., Barykin, Evgeny P., Varshavskaya, Kseniya B., Dalina, Alexandra A., Mitkevich, Vladimir A., Makarov, Alexander A., Petrushanko, Irina Yu.
Publicado 2022

Phosphorylation of the Amyloid-Beta Peptide Inhibits Zinc-Dependent Aggregation, Prevents Na,K-ATPase Inhibition, and Reduces Cerebral Plaque Deposition

por Barykin, Evgeny P., Petrushanko, Irina Y., Kozin, Sergey A., Telegin, Georgy B., Chernov, Alexander S., Lopina, Olga D., Radko, Sergey P., Mitkevich, Vladimir A., Makarov, Alexander A.
Publicado 2018

Zn-dependent β-amyloid Aggregation and its Reversal by the Tetrapeptide HAEE

por Mitkevich, Vladimir A, Barykin, Evgeny P, Eremina, Svetlana, Pani, Bibhusita, Katkova-Zhukotskaya, Olga, Polshakov, Vladimir I, Adzhubei, Alexei A, Kozin, Sergey A, Mironov, Alexander S, Makarov, Alexander A, Nudler, Evgeny
Publicado 2023

Tetrapeptide Ac-HAEE-NH(2) Protects α4β2 nAChR from Inhibition by Aβ

por Barykin, Evgeny P., Garifulina, Aleksandra I., Tolstova, Anna P., Anashkina, Anastasia A., Adzhubei, Alexei A., Mezentsev, Yuri V., Shelukhina, Irina V., Kozin, Sergey A., Tsetlin, Victor I., Makarov, Alexander A.
Publicado 2020

Snake Toxins Labeled by Green Fluorescent Protein or Its Synthetic Chromophore are New Probes for Nicotinic acetylcholine Receptors

por Kasheverov, Igor E., Kuzmenkov, Alexey I., Kudryavtsev, Denis S., Chudetskiy, Ivan S., Shelukhina, Irina V., Barykin, Evgeny P., Ivanov, Igor A., Siniavin, Andrei E., Ziganshin, Rustam H., Baranov, Mikhail S., Tsetlin, Victor I., Vassilevski, Alexander A., Utkin, Yuri N.
Publicado 2021

Na,K-ATPase Acts as a Beta-Amyloid Receptor Triggering Src Kinase Activation

por Petrushanko, Irina Yu., Tverskoi, Artem M., Barykin, Evgeny P., Petrovskaya, Aleksandra V., Strelkova, Maria A., Leonova, Olga G., Anashkina, Anastasia A., Tolstova, Anna P., Adzhubei, Alexei A., Bogdanova, Anna Yu., Makarov, Alexander A., Mitkevich, Vladimir A.
Publicado 2022

Isomerization of Asp7 in Beta-Amyloid Enhances Inhibition of the α7 Nicotinic Receptor and Promotes Neurotoxicity

por Barykin, Evgeny P., Garifulina, Alexandra I., Kruykova, Elena V., Spirova, Ekaterina N., Anashkina, Anastasia A., Adzhubei, Alexei A., Shelukhina, Irina V., Kasheverov, Igor E., Mitkevich, Vladimir A., Kozin, Sergey A., Hollmann, Michael, Tsetlin, Victor I., Makarov, Alexander A.
Publicado 2019

The Dynamics of β-Amyloid Proteoforms Accumulation in the Brain of a 5xFAD Mouse Model of Alzheimer’s Disease

por Bugrova, Anna E., Strelnikova, Polina A., Indeykina, Maria I., Kononikhin, Alexey S., Zakharova, Natalia V., Brzhozovskiy, Alexander G., Barykin, Evgeny P., Pekov, Stanislav I., Gavrish, Maria S., Babaev, Alexey A., Kosyreva, Anna M., Morozova, Anna Y., Degterev, Daniil A., Mitkevich, Vladimir A., Popov, Igor A., Makarov, Alexander A., Nikolaev, Evgeny N.
Publicado 2021