Novel Biphenyl Amines Inhibit Oestrogen Receptor (ER)-α in ER-Positive Mammary Carcinoma Cells

por Basappa, Basappa, Chumadathil Pookunoth, Baburajeev, Shinduvalli Kempasiddegowda, Mamatha, Knchugarakoppal Subbegowda, Rangappa, Lobie, Peter E., Pandey, Vijay
Publicado 2021

New Heparanase-Inhibiting Triazolo-Thiadiazoles Attenuate Primary Tumor Growth and Metastasis

por Barash, Uri, Rangappa, Shobith, Mohan, Chakrabhavi Dhananjaya, Vishwanath, Divakar, Boyango, Ilanit, Basappa, Basappa, Vlodavsky, Israel, Rangappa, Kanchugarakoppal S.
Publicado 2021

Inhibition of BAD-Ser99 phosphorylation synergizes with PARP inhibition to ablate PTEN-deficient endometrial carcinoma

por Zhang, Xi, Huang, Peng, Wang, Liqiong, Chen, Shu, Basappa, Basappa, Zhu, Tao, Lobie, Peter E., Pandey, Vijay
Publicado 2022

Design and Activity of Novel Oxadiazole Based Compounds That Target Poly(ADP-ribose) Polymerase

por Vishwanath, Divakar, Girimanchanaika, Swamy S., Dukanya, Dukanya, Rangappa, Shobith, Yang, Ji-Rui, Pandey, Vijay, Lobie, Peter E., Basappa, Basappa
Publicado 2022

Discovery of Hybrid Thiouracil–Coumarin Conjugates as Potential Novel Anti-SARS-CoV-2 Agents Targeting the Virus’s Polymerase “RdRp” as a Confirmed Interacting Biomolecule

por Vishwanath, Divakar, Shete-Aich, Anita, Honnegowda, Manjunath B., Anand, Mahesh Padukudru, Chidambaram, Saravana Babu, Sapkal, Gajanan, Basappa, Basappa, Yadav, Pragya D.
Publicado 2023

Combined inhibition of BADSer99 phosphorylation and PARP ablates models of recurrent ovarian carcinoma

por Zhang, Xi, Wang, Liqiong, Chen, Shu, Huang, Peng, Ma, Lan, Ding, Hui, Basappa, Basappa, Zhu, Tao, Lobie, Peter E., Pandey, Vijay
Publicado 2022

Methyl-Thiol-Bridged Oxadiazole and Triazole Heterocycles as Inhibitors of NF-κB in Chronic Myelogenous Leukemia Cells

por Basappa, Basappa, Jung, Young Yun, Ravish, Akshay, Xi, Zhang, Swamynayaka, Ananda, Madegowda, Mahendra, Pandey, Vijay, Lobie, Peter E., Sethi, Gautam, Ahn, Kwang Seok
Publicado 2023

Electrochemical Synthesis of New Isoxazoles and Triazoles Tethered with Thiouracil Base as Inhibitors of Histone Deacetylases in Human Breast Cancer Cells

por Vishwanath, Divakar, Xi, Zhang, Ravish, Akshay, Mohan, Arunkumar, Basappa, Shreeja, Krishnamurthy, Niranjan Pattehalli, Gaonkar, Santosh L., Pandey, Vijay, Lobie, Peter E., Basappa, Basappa
Publicado 2023

Trefoil factor 3 promotes pancreatic carcinoma progression via WNT pathway activation mediated by enhanced WNT ligand expression

por Cheng, Feifei, Wang, Xuejuan, Chiou, Yi-Shiou, He, Chuyu, Guo, Hui, Tan, Yan Qin, Basappa, Basappa, Zhu, Tao, Pandey, Vijay, Lobie, Peter E.
Publicado 2022

Investigation of NPB Analogs That Target Phosphorylation of BAD-Ser99 in Human Mammary Carcinoma Cells

por Girimanchanaika, Swamy Savvemala, Dukanya, Dukanya, Swamynayaka, Ananda, Govindachar, Divya Maldepalli, Madegowda, Mahendra, Periyasamy, Ganga, Rangappa, Kanchugarakoppal Subbegowda, Pandey, Vijay, Lobie, Peter E., Basappa, Basappa
Publicado 2021

Development of Piperazine- and Oxazine-Linked Pyrimidines as p65 Subunit Binders of NF–κB in Human Breast Cancer Cells

por Ravish, Akshay, Narasimhachar, Bhanuprakash C., Xi, Zhang, Vishwanath, Divakar, Mohan, Arunkumar, Gaonkar, Santosh L., Chandrashekara, Paduvalahippe Gowdegowda, Ahn, Kwang Seok, Pandey, Vijay, Lobie, Peter E., Basappa, Basappa
Publicado 2023

Discovery of Pyrimidine- and Coumarin-Linked Hybrid Molecules as Inducers of JNK Phosphorylation through ROS Generation in Breast Cancer Cells

por Kim, Na Young, Vishwanath, Divakar, Xi, Zhang, Nagaraja, Omantheswara, Swamynayaka, Ananda, Kumar Harish, Keshav, Basappa, Shreeja, Madegowda, Mahendra, Pandey, Vijay, Sethi, Gautam, Lobie, Peter E., Ahn, Kwang Seok, Basappa, Basappa
Publicado 2023

De Novo Design of Imidazopyridine-Tethered Pyrazolines That Target Phosphorylation of STAT3 in Human Breast Cancer Cells

por Ravish, Akshay, Shivakumar, Rashmi, Xi, Zhang, Yang, Min Hee, Yang, Ji-Rui, Swamynayaka, Ananda, Nagaraja, Omantheswara, Madegowda, Mahendra, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Pandey, Vijay, Sethi, Gautam, Ahn, Kwang Seok, Lobie, Peter E., Basappa, Basappa
Publicado 2023

Development of 1-(4-(Substituted)piperazin-1-yl)-2-((2-((4-methoxybenzyl)thio)pyrimidin-4-yl)oxy)ethanones That Target Poly (ADP-Ribose) Polymerase in Human Breast Cancer Cells

por Deveshegowda, Suresha N., Metri, Prashant K., Shivakumar, Rashmi, Yang, Ji-Rui, Rangappa, Shobith, Swamynayaka, Ananda, Shanmugam, Muthu K., Nagaraja, Omantheswara, Madegowda, Mahendra, Babu Shubha, Priya, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Pandey, Vijay, Ahn, Kwang Seok, Lobie, Peter E., Basappa, Basappa
Publicado 2022

Nano-Zirconium Dioxide Catalyzed Multicomponent Synthesis of Bioactive Pyranopyrazoles That Target Cyclin Dependent Kinase 1 in Human Breast Cancer Cells

por Basappa, Basappa, Poonacha, Lisha K., Xi, Zhang, Vishwanath, Divakar, Yang, Ji-Rui, Nagaraja, Omantheswara, Swamynayaka, Ananda, Madegowda, Mahendra, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Gurudatt, Doddahosuru Mahadevappa, Pandey, Vijay, Shivananju, Nanjundaswamy, Ahn, Kwang Seok, Sethi, Gautam, Lobie, Peter E., Shubha, Priya Babu
Publicado 2023