Inhibition of SARS-CoV-2 infection in cellular systems using engineered trimeric receptor-binding domain of spike protein

por Liu, Angela Rose, Basavarajappa, Shrikanth C., Sarkar, Nandini, Bruchez, Anna, Ramakrishnan, Parameswaran
Publicado 2023

Molecular dynamics simulations and functional studies reveal that hBD-2 binds SARS-CoV-2 spike RBD and blocks viral entry into ACE2 expressing cells

por Zhang, Liqun, Ghosh, Santosh K., Basavarajappa, Shrikanth C., Muller-Greven, Jeannine, Penfield, Jackson, Brewer, Ann, Ramakrishnan, Parameswaran, Buck, Matthias, Weinberg, Aaron
Publicado 2021

HBD-2 binds SARS-CoV-2 RBD and blocks viral entry: Strategy to combat COVID-19

por Zhang, Liqun, Ghosh, Santosh K., Basavarajappa, Shrikanth C., Chen, Yinghua, Shrestha, Pravesh, Penfield, Jackson, Brewer, Ann, Ramakrishnan, Parameswaran, Buck, Matthias, Weinberg, Aaron
Publicado 2022

Trimeric receptor-binding domain of SARS-CoV-2 acts as a potent inhibitor of ACE2 receptor-mediated viral entry

por Basavarajappa, Shrikanth C., Liu, Angela Rose, Bruchez, Anna, Li, Zhenlu, Suzart, Vinicius G., Liu, Zhonghua, Chen, Yinghua, Xiao, Tsan Sam, Buck, Matthias, Ramakrishnan, Parameswaran
Publicado 2022