Editing the genome of hiPSC with CRISPR/Cas9: disease models

por Bassett, Andrew R.
Publicado 2017

A Genome-Wide CRISPR Library for High-Throughput Genetic Screening in Drosophila Cells

por Bassett, Andrew R., Kong, Lesheng, Liu, Ji-Long
Publicado 2015

The Chromatin Remodelling Factor dATRX Is Involved in Heterochromatin Formation

por Bassett, Andrew R., Cooper, Sarah E., Ragab, Anan, Travers, Andrew A.
Publicado 2008

Highly Efficient Targeted Mutagenesis of Drosophila with the CRISPR/Cas9 System

por Bassett, Andrew R., Tibbit, Charlotte, Ponting, Chris P., Liu, Ji-Long
Publicado 2013

Mutagenesis and homologous recombination in Drosophila cell lines using CRISPR/Cas9

por Bassett, Andrew R., Tibbit, Charlotte, Ponting, Chris P., Liu, Ji-Long
Publicado 2013

Highly Efficient Targeted Mutagenesis of Drosophila with the CRISPR/Cas9 System

por Bassett, Andrew R., Tibbit, Charlotte, Ponting, Chris P., Liu, Ji-Long
Publicado 2014

Screening for functional transcriptional and splicing regulatory variants with GenIE

por Cooper, Sarah E, Schwartzentruber, Jeremy, Bello, Erica, Coomber, Eve L, Bassett, Andrew R
Publicado 2020

INSIGHT: A population-scale COVID-19 testing strategy combining point-of-care diagnosis with centralized high-throughput sequencing

por Wu, Qianxin, Suo, Chenqu, Brown, Tom, Wang, Tengyao, Teichmann, Sarah A., Bassett, Andrew R.
Publicado 2021

Identification and Properties of 1,119 Candidate LincRNA Loci in the Drosophila melanogaster Genome

por Young, Robert S., Marques, Ana C., Tibbit, Charlotte, Haerty, Wilfried, Bassett, Andrew R., Liu, Ji-Long, Ponting, Chris P.
Publicado 2012

Mitochondrial and Endoplasmic Reticulum Stress Trigger Triglyceride Accumulation in Models of Parkinson’s Disease Independent of Mutations in MAPT

por Fernandes, Hugo J. R., Kent, Josh P., Bruntraeger, Michaela, Bassett, Andrew R., Koulman, Albert, Metzakopian, Emmanouil, Snowden, Stuart G.
Publicado 2023

Single-cell transcriptomics defines an improved, validated monoculture protocol for differentiation of human iPSC to microglia

por Washer, Sam J., Perez-Alcantara, Marta, Chen, Yixi, Steer, Juliette, James, William S., Trynka, Gosia, Bassett, Andrew R., Cowley, Sally A.
Publicado 2022

Most microRNAs in the single-cell alga Chlamydomonas reinhardtii are produced by Dicer-like 3-mediated cleavage of introns and untranslated regions of coding RNAs

por Valli, Adrian A., Santos, Bruno A.C.M., Hnatova, Silvia, Bassett, Andrew R., Molnar, Attila, Chung, Betty Y., Baulcombe, David C.
Publicado 2016

The MITF-SOX10 regulated long non-coding RNA DIRC3 is a melanoma tumour suppressor

por Coe, Elizabeth A., Tan, Jennifer Y., Shapiro, Michael, Louphrasitthiphol, Pakavarin, Bassett, Andrew R., Marques, Ana C., Goding, Colin R., Vance, Keith W.
Publicado 2019

The Ncoa7 locus regulates V-ATPase formation and function, neurodevelopment and behaviour

por Castroflorio, Enrico, den Hoed, Joery, Svistunova, Daria, Finelli, Mattéa J., Cebrian-Serrano, Alberto, Corrochano, Silvia, Bassett, Andrew R., Davies, Benjamin, Oliver, Peter L.
Publicado 2020

Substantial somatic genomic variation and selection for BCOR mutations in human induced pluripotent stem cells

por Rouhani, Foad J., Zou, Xueqing, Danecek, Petr, Badja, Cherif, Amarante, Tauanne Dias, Koh, Gene, Wu, Qianxin, Memari, Yasin, Durbin, Richard, Martincorena, Inigo, Bassett, Andrew R., Gaffney, Daniel, Nik-Zainal, Serena
Publicado 2022

Understanding functional miRNA–target interactions in vivo by site-specific genome engineering

por Bassett, Andrew R., Azzam, Ghows, Wheatley, Lucy, Tibbit, Charlotte, Rajakumar, Timothy, McGowan, Simon, Stanger, Nathan, Ewels, Philip Andrew, Taylor, Stephen, Ponting, Chris P., Liu, Ji-Long, Sauka-Spengler, Tatjana, Fulga, Tudor A.
Publicado 2014

Considerations when investigating lncRNA function in vivo

por Bassett, Andrew R, Akhtar, Asifa, Barlow, Denise P, Bird, Adrian P, Brockdorff, Neil, Duboule, Denis, Ephrussi, Anne, Ferguson-Smith, Anne C, Gingeras, Thomas R, Haerty, Wilfried, Higgs, Douglas R, Miska, Eric A, Ponting, Chris P
Publicado 2014

In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering

por Wu, Qianxin, Ferry, Quentin R. V., Baeumler, Toni A., Michaels, Yale S., Vitsios, Dimitrios M., Habib, Omer, Arnold, Roland, Jiang, Xiaowei, Maio, Stefano, Steinkraus, Bruno R., Tapia, Marta, Piazza, Paolo, Xu, Ni, Holländer, Georg A., Milne, Thomas A., Kim, Jin-Soo, Enright, Anton J., Bassett, Andrew R., Fulga, Tudor A.
Publicado 2017