Desmin forms toxic, seeding-competent amyloid aggregates that persist in muscle fibers

por Kedia, Niraja, Arhzaouy, Khalid, Pittman, Sara K., Sun, Yuanzi, Batchelor, Mark, Weihl, Conrad C., Bieschke, Jan
Publicado 2019

Bank vole prion protein extends the use of RT-QuIC assays to detect prions in a range of inherited prion diseases

por Mok, Tze How, Nihat, Akin, Luk, Connie, Sequeira, Danielle, Batchelor, Mark, Mead, Simon, Collinge, John, Jackson, Graham S.
Publicado 2021

Structural effects of the highly protective V127 polymorphism on human prion protein

por Hosszu, Laszlo L. P., Conners, Rebecca, Sangar, Daljit, Batchelor, Mark, Sawyer, Elizabeth B., Fisher, Stuart, Cliff, Matthew J., Hounslow, Andrea M., McAuley, Katherine, Leo Brady, R., Jackson, Graham S., Bieschke, Jan, Waltho, Jonathan P., Collinge, John
Publicado 2020

N-terminal Domain of Prion Protein Directs Its Oligomeric Association

por Trevitt, Clare R., Hosszu, Laszlo L. P., Batchelor, Mark, Panico, Silvia, Terry, Cassandra, Nicoll, Andrew J., Risse, Emmanuel, Taylor, William A., Sandberg, Malin K., Al-Doujaily, Huda, Linehan, Jacqueline M., Saibil, Helen R., Scott, David J., Collinge, John, Waltho, Jonathan P., Clarke, Anthony R.
Publicado 2014

A systematic investigation of production of synthetic prions from recombinant prion protein

por Schmidt, Christian, Fizet, Jeremie, Properzi, Francesca, Batchelor, Mark, Sandberg, Malin K., Edgeworth, Julie A., Afran, Louise, Ho, Sammy, Badhan, Anjna, Klier, Steffi, Linehan, Jacqueline M., Brandner, Sebastian, Hosszu, Laszlo L. P., Tattum, M. Howard, Jat, Parmjit, Clarke, Anthony R., Klöhn, Peter C., Wadsworth, Jonathan D. F., Jackson, Graham S., Collinge, John
Publicado 2015

Seed amplification and neurodegeneration marker trajectories in individuals at risk of prion disease

por Mok, Tze How, Nihat, Akin, Majbour, Nour, Sequeira, Danielle, Holm-Mercer, Leah, Coysh, Thomas, Darwent, Lee, Batchelor, Mark, Groveman, Bradley R, Orr, Christina D, Hughson, Andrew G, Heslegrave, Amanda, Laban, Rhiannon, Veleva, Elena, Paterson, Ross W, Keshavan, Ashvini, Schott, Jonathan M, Swift, Imogen J, Heller, Carolin, Rohrer, Jonathan D, Gerhard, Alexander, Butler, Christopher, Rowe, James B, Masellis, Mario, Chapman, Miles, Lunn, Michael P, Bieschke, Jan, Jackson, Graham S, Zetterberg, Henrik, Caughey, Byron, Rudge, Peter, Collinge, John, Mead, Simon
Publicado 2023