Defining the Threshold IL-2 Signal Required for Induction of Selective Treg Cell Responses Using Engineered IL-2 Muteins

por Ghelani, Aazam, Bates, Darren, Conner, Kip, Wu, Min-Zu, Lu, Jiamiao, Hu, Yi-Ling, Li, Chi-Ming, Chaudhry, Ashutosh, Sohn, Sue J.
Publicado 2020

Exploiting a natural conformational switch to engineer an Interleukin-2 superkine

por Levin, Aron M., Bates, Darren L., Ring, Aaron M., Krieg, Carsten, Lin, Jack T., Su, Leon, Moraga, Ignacio L., Raeber, Miro E., Bowman, Gregory R., Novick, Paul, Pande, Vijay S., Fathman, C. Garrison, Boyman, Onur, Garcia, K. Christopher
Publicado 2012

Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines

por Junttila, Ilkka S., Creusot, Remi J., Moraga, Ignacio, Bates, Darren L., Wong, Michael T., Alonso, Michael N., Suhoski, Megan M., Lupardus, Patrick, Meier-Schellersheim, Martin, Engleman, Edgar G., Utz, Paul J., Fathman, C. Garrison, Paul, William E., Garcia, K. Christopher
Publicado 2012

Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor

por Min, Xiaoshan, Yie, Junming, Wang, Jinghong, Chung, Ben C., Huang, Ching-Shin, Xu, Haoda, Yang, Jie, Deng, Liying, Lin, Joanne, Chen, Qing, Abbott, Christina M., Gundel, Caroline, Thibault, Stephen A., Meng, Tina, Bates, Darren L., Lloyd, David J., Véniant, Murielle M., Wang, Zhulun
Publicado 2020