Engineering of chimeric peptides as antagonists for the G protein-coupled receptor, RXFP4

por Praveen, Praveen, Bathgate, Ross A. D., Hossain, Mohammed Akhter
Publicado 2019

C-Terminus of the B-Chain of Relaxin-3 Is Important for Receptor Activity

por Shabanpoor, Fazel, Bathgate, Ross A. D., Wade, John D., Hossain, Mohammed Akhter
Publicado 2013

Targeted viral vector transduction of relaxin-3 neurons in the rat nucleus incertus using a novel cell-type specific promoter

por Wykes, Alexander D., Ma, Sherie, Bathgate, Ross A.D., Gundlach, Andrew L.
Publicado 2019

In a Class of Their Own – RXFP1 and RXFP2 are Unique Members of the LGR Family

por Petrie, Emma J., Lagaida, Samantha, Sethi, Ashish, Bathgate, Ross A. D., Gooley, Paul R.
Publicado 2015

Using the novel HiBiT tag to label cell surface relaxin receptors for BRET proximity analysis

por Hoare, Bradley L., Kocan, Martina, Bruell, Shoni, Scott, Daniel J., Bathgate, Ross A. D.
Publicado 2019

The Structural Determinants of Insulin-Like Peptide 3 Activity

por Bathgate, Ross A. D., Zhang, Soude, Hughes, Richard A., Rosengren, K. Johan, Wade, John D.
Publicado 2012

Characterisation of a cell-free synthesised G-protein coupled receptor

por Shilling, Patrick J., Bumbak, Fabian, Scott, Daniel J., Bathgate, Ross A. D., Gooley, Paul R.
Publicado 2017

A Real-Time, Plate-Based BRET Assay for Detection of cGMP in Primary Cells

por Valkovic, Adam L., Kocan, Martina, Hoare, Brad, Marshall, Sarah, Scott, Daniel J., Bathgate, Ross A. D.
Publicado 2022

Further Developments towards a Minimal Potent Derivative of Human Relaxin-2

por Handley, Thomas N. G., Praveen, Praveen, Tailhades, Julien, Wu, Hongkang, Bathgate, Ross A. D., Hossain, Mohammed Akhter
Publicado 2023

Synthetic Covalently Linked Dimeric Form of H2 Relaxin Retains Native RXFP1 Activity and Has Improved In Vitro Serum Stability

por Nair, Vinojini B., Bathgate, Ross A. D., Separovic, Frances, Samuel, Chrishan S., Hossain, Mohammed Akhter, Wade, John D.
Publicado 2015

Evidence that RXFP4 is located in enterochromaffin cells and can regulate production and release of serotonin

por Fernando, Shalinda J.A., Wang, Qian, Hay, Debbie L., Bathgate, Ross A.D., Shepherd, Peter R., Lee, Kate L.
Publicado 2023

A Lipidated Single-B-Chain Derivative of Relaxin Exhibits Improved In Vitro Serum Stability without Altering Activity

por Praveen, Praveen, Wang, Chao, Handley, Thomas N. G., Wu, Hongkang, Samuel, Chrishan S., Bathgate, Ross A. D., Hossain, Mohammed Akhter
Publicado 2023

Relaxin Signals through a RXFP1-pERK-nNOS-NO-cGMP-Dependent Pathway to Up-Regulate Matrix Metalloproteinases: The Additional Involvement of iNOS

por Chow, Bryna Suet Man, Chew, Elaine Guo Yan, Zhao, Chongxin, Bathgate, Ross A. D., Hewitson, Tim D., Samuel, Chrishan S.
Publicado 2012

Real‐time examination of cAMP activity at relaxin family peptide receptors using a BRET‐based biosensor

por Valkovic, Adam L., Leckey, Miranda B., Whitehead, Alice R., Hossain, Mohammed A., Inoue, Asuka, Kocan, Martina, Bathgate, Ross A. D.
Publicado 2018

Silencing Relaxin-3 in Nucleus Incertus of Adult Rodents: A Viral Vector-based Approach to Investigate Neuropeptide Function

por Callander, Gabrielle E., Ma, Sherie, Ganella, Despina E., Wimmer, Verena C., Gundlach, Andrew L., Thomas, Walter G., Bathgate, Ross A. D.
Publicado 2012

Development of Relaxin-3 Agonists and Antagonists Based on Grafted Disulfide-Stabilized Scaffolds

por Lee, Han Siean, Postan, Michael, Song, Angela, Clark, Richard J., Bathgate, Ross A. D., Haugaard-Kedström, Linda M., Rosengren, K. Johan
Publicado 2020

Exploring the Use of Helicogenic Amino Acids for Optimising Single Chain Relaxin-3 Peptide Agonists

por Lee, Han Siean, Wang, Shu Hui, Daniel, James T., Hossain, Mohammed Akhter, Clark, Richard J., Bathgate, Ross A. D., Rosengren, K. Johan
Publicado 2020

The complex binding mode of the peptide hormone H2 relaxin to its receptor RXFP1

por Sethi, Ashish, Bruell, Shoni, Patil, Nitin, Hossain, Mohammed Akhter, Scott, Daniel J., Petrie, Emma J., Bathgate, Ross A. D., Gooley, Paul R.
Publicado 2016

Synthetic short-chain peptide analogues of H1 relaxin lack affinity for the RXFP1 receptor and relaxin-like bioactivity. Clues to a better understanding of relaxin agonist design

por D'Ercole, Annunziata, Nistri, Silvia, Pacini, Lorenzo, Carotenuto, Alfonso, Santoro, Federica, Papini, Anna Maria, Bathgate, Ross A. D., Bani, Daniele, Rovero, Paolo
Publicado 2022

Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3

por Bathgate, Ross A. D., Oh, Maria H. Y., Ling, W. J. Jason, Kaas, Quentin, Hossain, M. Akhter, Gooley, Paul R., Rosengren, K. Johan
Publicado 2013