Development of Copper Complexes with Diimines and Dipicolinate as Anticancer Cytotoxic Agents

por Alvarez, Natalia, Rocha, Analu, Collazo, Victoria, Ellena, Javier, Costa-Filho, Antonio J., Batista, Alzir A., Facchin, Gianella
Publicado 2023

New Copper(II)-L-Dipeptide-Bathophenanthroline Complexes as Potential Anticancer Agents—Synthesis, Characterization and Cytotoxicity Studies—And Comparative DNA-Binding Study of Re...

por Fernández, Carlos Y., Alvarez, Natalia, Rocha, Analu, Ellena, Javier, Costa-Filho, Antonio J., Batista, Alzir A., Facchin, Gianella
Publicado 2023

Nucleobase Derivatives as Building Blocks to Form Ru(II)-Based Complexes with High Cytotoxicity

por Carvalho, Diogo E. L., Oliveira, Katia M., Bomfim, Larissa M., Soares, Milena B. P., Bezerra, Daniel P., Batista, Alzir A., Correa, Rodrigo S.
Publicado 2020

A Novel Ruthenium(II) Complex With Lapachol Induces G2/M Phase Arrest Through Aurora-B Kinase Down-Regulation and ROS-Mediated Apoptosis in Human Prostate Adenocarcinoma Cells

por De Grandis, Rone A., Oliveira, Katia M., Guedes, Adriana P. M., dos Santos, Patrick W. S., Aissa, Alexandre F., Batista, Alzir A., Pavan, Fernando R.
Publicado 2021

Structural and Anticancer Studies of Methoxyflavone Derivative from Strychnos pseudoquina A.St.-Hil. (Loganiaceae) from Brazilian Cerrado

por Silva, Marianna C., Cunha, Gracielle, Firmino, Pollyana, Sallum, Loide O., Menezes, Antônio, Dutra, Jocely, de Araujo-Neto, João, Batista, Alzir A., Ellena, Javier, Napolitano, Hamilton B.
Publicado 2023

Synthesis, Characterization, Cytotoxic Activity, and Interactions with CT-DNA and BSA of Cationic Ruthenium(II) Complexes Containing Dppm and Quinoline Carboxylates

por da Silva, Edinaldo N., da Silva, Paulo A. B., Graminha, Angélica E., de Oliveira, Pollyanna F., Damasceno, Jaqueline L., Tavares, Denise C., Batista, Alzir A., Von Poelhsitz, Gustavo
Publicado 2017

Ru(II)-thymine complex causes DNA damage and apoptotic cell death in human colon carcinoma HCT116 cells mediated by JNK/p38/ERK1/2 via a p53-independent signaling

por Silva, Suellen L. R., Baliza, Ingrid R. S., Dias, Rosane B., Sales, Caroline B. S., Rocha, Clarissa A. Gurgel, Soares, Milena B. P., Correa, Rodrigo S., Batista, Alzir A., Bezerra, Daniel P.
Publicado 2019

Ruthenium(II) complexes with 6-methyl-2-thiouracil selectively reduce cell proliferation, cause DNA double-strand break and trigger caspase-mediated apoptosis through JNK/p38 pathw...

por Bomfim, Larissa M., de Araujo, Fênix A., Dias, Rosane B., Sales, Caroline B. S., Rocha, Clarissa A. Gurgel, Correa, Rodrigo S., Soares, Milena B. P., Batista, Alzir A., Bezerra, Daniel P.
Publicado 2019

Cytotoxicity and anti-tumor effects of new ruthenium complexes on triple negative breast cancer cells

por Popolin, Cecília P., Reis, João P. B., Becceneri, Amanda B., Graminha, Angélica E., Almeida, Márcio A. P., Corrêa, Rodrigo S., Colina-Vegas, Legna A., Ellena, Javier, Batista, Alzir A., Cominetti, Márcia R.
Publicado 2017

Ruthenium Complexes With Piplartine Cause Apoptosis Through MAPK Signaling by a p53-Dependent Pathway in Human Colon Carcinoma Cells and Inhibit Tumor Development in a Xenograft Mo...

por Baliza, Ingrid R. S., Silva, Suellen L. R., Santos, Luciano de S., Neto, João H. Araujo, Dias, Rosane B., Sales, Caroline B. S., Rocha, Clarissa A. Gurgel, Soares, Milena B. P., Batista, Alzir A., Bezerra, Daniel P.
Publicado 2019

Ruthenium Complexes Containing Heterocyclic Thioamidates Trigger Caspase-Mediated Apoptosis Through MAPK Signaling in Human Hepatocellular Carcinoma Cells

por Neves, Sara P., de Carvalho, Nanashara C., da Silva, Monize M., Rodrigues, Ana Carolina B. C., Bomfim, Larissa M., Dias, Rosane B., Sales, Caroline B. S., Rocha, Clarissa A. Gurgel, Soares, Milena B. P., Batista, Alzir A., Bezerra, Daniel P.
Publicado 2019

In Vitro and In Vivo Activities of Ruthenium(II) Phosphine/Diimine/Picolinate Complexes (SCAR) against Mycobacterium tuberculosis

por Pavan, Fernando R., Poelhsitz, Gustavo V., da Cunha, Lucas V. P., Barbosa, Marilia I. F., Leite, Sergio R. A., Batista, Alzir A., Cho, Sang H., Franzblau, Scott G., de Camargo, Mariana S., Resende, Flávia A., Varanda, Eliana A., Leite, Clarice Q. F.
Publicado 2013

Novel piplartine-containing ruthenium complexes: synthesis, cell growth inhibition, apoptosis induction and ROS production on HCT116 cells

por D’Sousa Costa, Cinara O., Araujo Neto, João H., Baliza, Ingrid R.S., Dias, Rosane B., Valverde, Ludmila de F., Vidal, Manuela T.A., Sales, Caroline B.S., Rocha, Clarissa A.G., Moreira, Diogo R.M., Soares, Milena B.P., Batista, Alzir A., Bezerra, Daniel P.
Publicado 2017