Using Big Data Analytics to “Back Engineer” Protein Conformational Selection Mechanisms

por Gupta, Shivangi, Baudry, Jerome, Menon, Vineetha
Publicado 2022

Big Data analytics for improved prediction of ligand binding and conformational selection

por Gupta, Shivangi, Baudry, Jerome, Menon, Vineetha
Publicado 2023

Turning crowds into communities: The collectives of online citizen science

por Baudry, Jérôme, Tancoigne, Élise, Strasser, Bruno J
Publicado 2021

Novel Big Data-Driven Machine Learning Models for Drug Discovery Application

por Sripriya Akondi, Vishnu, Menon, Vineetha, Baudry, Jerome, Whittle, Jana
Publicado 2022

Discovery of an Inhibitor of Z-Alpha1 Antitrypsin Polymerization

por Berthelier, Valerie, Harris, Jason Brett, Estenson, Kasey Noel, Baudry, Jerome
Publicado 2015

Homology Modeling of the CheW Coupling Protein of the Chemotaxis Signaling Complex

por Cashman, Derek J., Ortega, Davi R., Zhulin, Igor B., Baudry, Jerome
Publicado 2013

Sequential Dynamics of Stearoyl-CoA Desaturase-1(SCD1)/Ligand Binding and Unbinding Mechanism: A Computational Study

por Petroff, Anna B., Weir, Rebecca L., Yates, Charles R., Ng, Joseph D., Baudry, Jerome
Publicado 2021

Conformational Coupling between Receptor and Kinase Binding Sites through a Conserved Salt Bridge in a Signaling Complex Scaffold Protein

por Ortega, Davi R., Mo, Guoya, Lee, Kwangwoon, Zhou, Hongjun, Baudry, Jerome, Dahlquist, Frederick W., Zhulin, Igor B.
Publicado 2013

Computationally identified novel agonists for GPRC6A

por Pi, Min, Kapoor, Karan, Ye, Ruisong, Hwang, Dong-Jin, Miller, Duane D., Smith, Jeremy C., Baudry, Jerome, Quarles, L. Darryl
Publicado 2018

Determining anion-quadrupole interactions among protein, DNA, and ligand molecules

por Harris, Jason B, Jenkins, David D, Reyles, Jonathan, Rickett, Stephanie, Utley, Jordan M, Howell, Elizabeth E, Baudry, Jerome, Hinde, Robert J
Publicado 2011

The quinic acid derivative KZ-41 prevents glucose-induced caspase-3 activation in retinal endothelial cells through an IGF-1 receptor dependent mechanism

por He, Hui, Weir, Rebecca L., Toutounchian, Jordan J., Pagadala, Jayaprakash, Steinle, Jena J., Baudry, Jerome, Miller, Duane D., Yates, Charles R.
Publicado 2017

Quantifying online citizen science: Dynamics and demographics of public participation in science

por Strasser, Bruno J., Tancoigne, Elise, Baudry, Jérôme, Piguet, Steven, Spiers, Helen, Luis-Fernandez Marquez, José, Kasparian, Jérôme, Grey, François, Anderson, David, Lintott, Chris
Publicado 2023

A computationally identified compound antagonizes excess FGF-23 signaling in renal tubules and a mouse model of hypophosphatemia

por Xiao, Zhousheng, Riccardi, Demian, Velazquez, Hector A., Chin, Ai L., Yates, Charles R., Carrick, Jesse D., Smith, Jeremy C., Baudry, Jerome, Quarles, L. Darryl
Publicado 2016

Piperazinobenzodiazepinones: New Encephalitic Alphavirus Inhibitors via Ring Expansion of 2-Dichloromethylquinazolinones

por Ryan, Michael C., Kim, Eunjung, Cao, Xufeng, Reichard, Walter, Ogorek, Tyler J., Das, Pronay, Jonsson, Colleen B., Baudry, Jerome, Chung, Donghoon, Golden, Jennifer E.
Publicado 2022

Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation

por Bensing, Barbara A., Stubbs, Haley E., Agarwal, Rupesh, Yamakawa, Izumi, Luong, Kelvin, Solakyildirim, Kemal, Yu, Hai, Hadadianpour, Azadeh, Castro, Manuel A., Fialkowski, Kevin P., Morrison, KeAndreya M., Wawrzak, Zdzislaw, Chen, Xi, Lebrilla, Carlito B., Baudry, Jerome, Smith, Jeremy C., Sullam, Paul M., Iverson, T. M.
Publicado 2022