Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening

por Chopra, Ashima, Bauman, Joseph D., Ruiz, Francesc X., Arnold, Eddy
Publicado 2023

HIV-1 reverse transcriptase complex with DNA and nevirapine reveals nonnucleoside inhibition mechanism

por Das, Kalyan, Martinez, Sergio E., Bauman, Joseph D., Arnold, Eddy
Publicado 2012

Rapid experimental SAD phasing and hot-spot identification with halogenated fragments

por Bauman, Joseph D., Harrison, Jerry Joe E. K., Arnold, Eddy
Publicado 2016

Phenyl Substituted 4-Hydroxypyridazin-3(2H)-ones and 5-Hydroxypyrimidin-4(3H)-ones: Inhibitors of Influenza A Endonuclease

por Sagong, Hye Yeon, Bauman, Joseph D., Patel, Disha, Das, Kalyan, Arnold, Eddy, LaVoie, Edmond J.
Publicado 2014

Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase

por Kuroda, Daniel G., Bauman, Joseph D., Challa, J. Reddy, Patel, Disha, Troxler, Thomas, Das, Kalyan, Arnold, Eddy, Hochstrasser, Robin M.
Publicado 2013

Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT)

por Harrison, Jerry Joe E. K., Tuske, Steve, Das, Kalyan, Ruiz, Francesc X., Bauman, Joseph D., Boyer, Paul L., DeStefano, Jeffrey J., Hughes, Stephen H., Arnold, Eddy
Publicado 2021

Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation

por Harrison, Jerry Joe E. K., Passos, Dario Oliveira, Bruhn, Jessica F., Bauman, Joseph D., Tuberty, Lynda, DeStefano, Jeffrey J., Ruiz, Francesc Xavier, Lyumkis, Dmitry, Arnold, Eddy
Publicado 2022

Crystal engineering of HIV-1 reverse transcriptase for structure-based drug design

por Bauman, Joseph D., Das, Kalyan, Ho, William C., Baweja, Mukta, Himmel, Daniel M., Clark, Arthur D., Oren, Deena A., Boyer, Paul L., Hughes, Stephen H., Shatkin, Aaron J., Arnold, Eddy
Publicado 2008

A comparison of the ability of rilpivirine (TMC278) and selected analogues to inhibit clinically relevant HIV-1 reverse transcriptase mutants

por Johnson, Barry C, Pauly, Gary T, Rai, Ganesha, Patel, Disha, Bauman, Joseph D, Baker, Heather L, Das, Kalyan, Schneider, Joel P, Maloney, David J, Arnold, Eddy, Thomas, Craig J, Hughes, Stephen H
Publicado 2012

Integrative structural biology studies of HIV-1 reverse transcriptase binding to a high-affinity DNA aptamer

por Tuske, Steve, Zheng, Jie, Olson, Erik D., Ruiz, Francesc X., Pascal, Bruce D., Hoang, Anthony, Bauman, Joseph D., Das, Kalyan, DeStefano, Jeffrey J., Musier-Forsyth, Karin, Griffin, Patrick R., Arnold, Eddy
Publicado 2020

Targeting HIV-1 Reverse Transcriptase Using a Fragment-Based Approach

por Mansouri, Mahta, Rumrill, Shawn, Dawson, Shane, Johnson, Adam, Pinson, Jo-Anne, Gunzburg, Menachem J., Latham, Catherine F., Barlow, Nicholas, Mbogo, George W., Ellenberg, Paula, Headey, Stephen J., Sluis-Cremer, Nicolas, Tyssen, David, Bauman, Joseph D., Ruiz, Francesc X., Arnold, Eddy, Chalmers, David K., Tachedjian, Gilda
Publicado 2023