Progression of Myeloproliferative Neoplasms (MPN): Diagnostic and Therapeutic Perspectives

por Baumeister, Julian, Chatain, Nicolas, Sofias, Alexandros Marios, Lammers, Twan, Koschmieder, Steffen
Publicado 2021

P988: MUTANT CALRETICULIN AND JAK2V617F DRIVER MUTATIONS INDUCE DISTINCT MITOTIC DEFECTS IN MYELOPROLIFERATIVE NEOPLASMS

por Holl, Kristin, Chatain, Nicolas, Brock, Nathalie, Krapp, Susanne, Baumeister, Julian, Koschmieder, Steffen, Antonin, Wolfram, Moreno-Andrés, Daniel
Publicado 2023

Targeting cytokine-induced leukemic stem cell persistence in chronic myeloid leukemia by IKK2-inhibition

por Bütow, Marlena, Testaquadra, Fabio J., Baumeister, Julian, Maié, Tiago, Chatain, Nicolas, Jaquet, Timo, Tillmann, Stefan, Crysandt, Martina, Costa, Ivan G., Brümmendorf, Tim H., Schemionek, Mirle
Publicado 2022

Differential roles of STAT1 and STAT2 in the sensitivity of JAK2V617F- vs. BCR-ABL-positive cells to interferon alpha

por Schubert, Claudia, Allhoff, Manuel, Tillmann, Stefan, Maié, Tiago, Costa, Ivan G., Lipka, Daniel B., Schemionek, Mirle, Feldberg, Kristina, Baumeister, Julian, Brümmendorf, Tim H., Chatain, Nicolas, Koschmieder, Steffen
Publicado 2019

Clonogenic assays improve determination of variant allele frequency of driver mutations in myeloproliferative neoplasms

por Kalmer, Milena, Pannen, Kristina, Lemanzyk, Rebecca, Wirths, Chiara, Baumeister, Julian, Maurer, Angela, Kricheldorf, Kim, Schifflers, Joelle, Gezer, Deniz, Isfort, Susanne, Brümmendorf, Tim H., Koschmieder, Steffen, Chatain, Nicolas
Publicado 2022

Cellular aging is accelerated in the malignant clone of myeloproliferative neoplasms

por Vieri, Margherita, Tharmapalan, Vithurithra, Kalmer, Milena, Baumeister, Julian, Nikolić, Miloš, Schnitker, Matthis, Kirschner, Martin, Flosdorf, Niclas, de Toledo, Marcelo A. S., Zenke, Martin, Koschmieder, Steffen, Brümmendorf, Tim H., Beier, Fabian, Wagner, Wolfgang
Publicado 2023

Nrf2 Is a Central Regulator of Metabolic Reprogramming of Myeloid-Derived Suppressor Cells in Steady State and Sepsis

por Ohl, Kim, Fragoulis, Athanassios, Klemm, Patricia, Baumeister, Julian, Klock, Wiebke, Verjans, Eva, Böll, Svenja, Möllmann, Julia, Lehrke, Michael, Costa, Ivan, Denecke, Bernd, Schippers, Angela, Roth, Johannes, Wagner, Norbert, Wruck, Christoph, Tenbrock, Klaus
Publicado 2018

Early and late stage MPN patients show distinct gene expression profiles in CD34(+) cells

por Baumeister, Julian, Maié, Tiago, Chatain, Nicolas, Gan, Lin, Weinbergerova, Barbora, de Toledo, Marcelo A. S., Eschweiler, Jörg, Maurer, Angela, Mayer, Jiri, Kubesova, Blanka, Racil, Zdenek, Schuppert, Andreas, Costa, Ivan, Koschmieder, Steffen, Brümmendorf, Tim H., Gezer, Deniz
Publicado 2021

The Unfolded Protein Response Is a Major Driver of LCN2 Expression in BCR–ABL- and JAK2V617F-Positive MPN

por Tillmann, Stefan, Olschok, Kathrin, Schröder, Sarah K., Bütow, Marlena, Baumeister, Julian, Kalmer, Milena, Preußger, Vera, Weinbergerova, Barbora, Kricheldorf, Kim, Mayer, Jiri, Kubesova, Blanka, Racil, Zdenek, Wessiepe, Martina, Eschweiler, Jörg, Isfort, Susanne, Brümmendorf, Tim H., Becker, Walter, Schemionek, Mirle, Weiskirchen, Ralf, Koschmieder, Steffen, Chatain, Nicolas
Publicado 2021

CALR frameshift mutations in MPN patient-derived iPSCs accelerate maturation of megakaryocytes

por Olschok, Kathrin, Han, Lijuan, de Toledo, Marcelo A.S., Böhnke, Janik, Graßhoff, Martin, Costa, Ivan G., Theocharides, Alexandre, Maurer, Angela, Schüler, Herdit M., Buhl, Eva Miriam, Pannen, Kristina, Baumeister, Julian, Kalmer, Milena, Gupta, Siddharth, Boor, Peter, Gezer, Deniz, Brümmendorf, Tim H., Zenke, Martin, Chatain, Nicolas, Koschmieder, Steffen
Publicado 2021