A Novel Shigella O-Polysaccharide–IpaB Conjugate Vaccine Elicits Robust Antibody Responses and Confers Protection against Multiple Shigella Serotypes

por Desalegn, Girmay, Kapoor, Neeraj, Pill-Pepe, Lucy, Bautista, Leslie, Yin, Lu, Ndungo, Esther, Oaks, Edwin V., Fairman, Jeff, Pasetti, Marcela F.
Publicado 2023

Non-Native Amino Acid Click Chemistry-Based Technology for Site-Specific Polysaccharide Conjugation to a Bacterial Protein Serving as Both Carrier and Vaccine Antigen

por Kapoor, Neeraj, Uchiyama, Satoshi, Pill, Lucy, Bautista, Leslie, Sedra, Angie, Yin, Lu, Regan, Maritoni, Chu, Ellen, Rabara, Taylor, Wong, Melissa, Davey, Peter, Fairman, Jeff, Nizet, Victor
Publicado 2022

Addition of Lauryldimethylamine N-Oxide (LDAO) to a Copper-Free Click Chemistry Reaction Improves the Conjugation Efficiency of a Cell-Free Generated CRM197 Variant to Clinically I...

por Bautista, Leslie, Pill-Pepe, Lucy, Kapoor, Neeraj, Snyder, Scott, Chu, Ellen, Agarwal, Paresh, Sardar, Mohammed, Arulkumar, Shylaja, Berges, Aym, Iverson, Mark, Behrens, Christopher, Marcq, Olivier, Fairman, Jeff
Publicado 2022

1047. Development of a Next Generation 30(+) Valent Pneumococcal Conjugate Vaccine (VAX-XP) Using Site-Specific Carrier Protein Conjugation

por Behrens, Chris, Fairman, Jeff, Agarwal, Paresh, Arulkumar, Shylaja, Barbanel, Sandrine, Bautista, Leslie, Berges, Aym, Burky, John, Davey, Peter, Grainger, Chris, Guo, Sherry, Iki, Sam, Iverson, Mark, Kapoor, Neeraj, Marcq, Olivier, Migone, Thi-Sau, Pill, Lucy, Sardar, Mohammed, Sauer, Paul, Wassil, James
Publicado 2021