N-Hydroxy-N-Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases

por Bautista-Aguilera, Óscar M., Alonso, José M., Catto, Marco, Iriepa, Isabel, Knez, Damijan, Gobec, Stanislav, Marco-Contelles, José
Publicado 2022

Triazolopyridopyrimidine: A New Scaffold for Dual-Target Small Molecules for Alzheimer’s Disease Therapy

por Zribi, Lazhar, Pachòn-Angona, Irene, Bautista-Aguilera, Òscar M., Diez-Iriepa, Daniel, Marco-Contelles, José, Ismaili, Lhassane, Iriepa, Isabel, Chabchoub, Fakher
Publicado 2020

Straightforward Synthesis of Bis[(trifluoromethyl)sulfonyl]ethylated Isocoumarins from 2-Ethynylbenzoates

por Petcu, A. Sonia, Lázaro-Milla, Carlos, Rodríguez, F. Javier, Iriepa, Isabel, Bautista-Aguilera, Óscar M., Aragoncillo, Cristina, Alonso, José M., Almendros, Pedro
Publicado 2023

Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer’s disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR ana...

por Bautista-Aguilera, Oscar M, Esteban, Gerard, Chioua, Mourad, Nikolic, Katarina, Agbaba, Danica, Moraleda, Ignacio, Iriepa, Isabel, Soriano, Elena, Samadi, Abdelouahid, Unzeta, Mercedes, Marco-Contelles, José
Publicado 2014

Label-Free Whole Cell Biosensing for High-Throughput Discovery of Activators and Inhibitors Targeting G Protein-Activated Inwardly Rectifying Potassium Channels

por Krebs, Katrin M., Pfeil, Eva M., Simon, Katharina, Grundmann, Manuel, Häberlein, Felix, Bautista-Aguilera, Oscar M., Gütschow, Michael, Weaver, C. David, Fleischmann, Bernd K., Kostenis, Evi
Publicado 2018

Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer’s Disease

por Dgachi, Youssef, Bautista-Aguilera, Oscar M., Benchekroun, Mohamed, Martin, Hélène, Bonet, Alexandre, Knez, Damijan, Godyń, Justyna, Malawska, Barbara, Gobec, Stanislav, Chioua, Mourad, Janockova, Jana, Soukup, Ondrej, Chabchoub, Fakher, Marco-Contelles, José, Ismaili, Lhassane
Publicado 2016

Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer’s Disease Therapy

por Bautista-Aguilera, Óscar M., Ismaili, Lhassane, Chioua, Mourad, Andrys, Rudolf, Schmidt, Monika, Bzonek, Petr, Martínez-Grau, María Ángeles, Beadle, Christopher D., Vetman, Tatiana, López-Muñoz, Francisco, Iriepa, Isabel, Refouvelet, Bernard, Musilek, Kamil, Marco-Contelles, José
Publicado 2020

In Vitro and In Silico ADME-Tox Profiling and Safety Significance of Multifunctional Monoamine Oxidase Inhibitors Targeting Neurodegenerative Diseases

por Więckowska, Anna, Szałaj, Natalia, Góral, Izabella, Bucki, Adam, Latacz, Gniewomir, Kiec-Kononowicz, Katarzyna, Bautista-Aguilera, Òscar. M., Romero, Alejandro, Ramos, Eva, Egea, Javier, Farré Alíns, Victor, González-Rodríguez, Águeda, López-Muñoz, Francisco, Chioua, Mourad, Marco-Contelles, José
Publicado 2020