The Heat-Stable Enterotoxin Receptor, Guanylyl Cyclase C, as a Pharmacological Target in Colorectal Cancer Immunotherapy: A Bench-to-Bedside Current Report

por Baybutt, Trevor R., Aka, Allison A., Snook, Adam E.
Publicado 2017

GUCY2C-directed CAR-T cells oppose colorectal cancer metastases without autoimmunity

por Magee, Michael S., Kraft, Crystal L., Abraham, Tara S., Baybutt, Trevor R., Marszalowicz, Glen P., Li, Peng, Waldman, Scott A., Snook, Adam E.
Publicado 2016

Split tolerance permits safe Ad5-GUCY2C-PADRE vaccine-induced T-cell responses in colon cancer patients

por Snook, Adam E., Baybutt, Trevor R., Xiang, Bo, Abraham, Tara S., Flickinger, John C., Hyslop, Terry, Zhan, Tingting, Kraft, Walter K., Sato, Takami, Waldman, Scott A.
Publicado 2019

A Phase I study of AD5-GUCY2C-PADRE in stage I and II colon cancer patients

por Snook, Adam, Baybutt, Trevor, Mastrangelo, Michael, Lewis, Nancy, Goldstein, Scott, Kraft, Walter, Oppong, Yaa, Hyslop, Terry, Myers, Ronald, Alexeev, Vitali, Eisenlohr, Laurence, Sato, Takami, Waldman, Scott
Publicado 2015

Chimeric adenoviral (Ad5.F35) and listeria vector prime-boost immunization is safe and effective for cancer immunotherapy

por Flickinger, John C., Staudt, Ross E., Singh, Jagmohan, Carlson, Robert D., Barton, Joshua R., Baybutt, Trevor R., Rappaport, Jeffrey A., Zalewski, Alicja, Pattison, Amanda, Waldman, Scott A., Snook, Adam E.
Publicado 2022

Chimeric Ad5.F35 vector evades anti-adenovirus serotype 5 neutralization opposing GUCY2C-targeted antitumor immunity

por Flickinger Jr, John C, Singh, Jagmohan, Carlson, Robert, Leong, Elinor, Baybutt, Trevor R, Barton, Joshua, Caparosa, Ellen, Pattison, Amanda, Rappaport, Jeffrey A, Roh, Jamin, Zhan, Tingting, Bashir, Babar, Waldman, Scott A, Snook, Adam E
Publicado 2020