Reactivity of 3-Ethoxycarbonyl Isoquinolinium Salts Towards Various Nucleophilic Reagents: Applications to the Synthesis of New 1,2-Dihydroisoquinoline-3-carboxylates

por Meziane, Mohamed Ameziane Aït Amer, Bazureau, Jean Pierre
Publicado 2002

A Practical Approach to New (5Z) 2-Alkylthio-5-arylmethylene-1-methyl-1,5-dihydro-4H-imidazol-4-one Derivatives

por Bourahla, Khadidja, Paquin, Ludovic, Lozach, Olivier, Meijer, Laurent, Carreaux, François, Bazureau, Jean Pierre
Publicado 2011

Preliminary Structure-Activity Relationship (SAR) of a Novel Series of Pyrazole SKF-96365 Analogues as Potential Store-Operated Calcium Entry (SOCE) Inhibitors

por Dago, Camille D., Maux, Paul Le, Roisnel, Thierry, Brigaudeau, Christophe, Bekro, Yves-Alain, Mignen, Olivier, Bazureau, Jean-Pierre
Publicado 2018

Microwave-Assisted Condensation Reactions of Acetophenone Derivatives and Activated Methylene Compounds with Aldehydes Catalyzed by Boric Acid under Solvent-Free Conditions

por Brun, Elodie, Safer, Abdelmounaim, Carreaux, François, Bourahla, Khadidja, L’helgoua’ch, Jean-Martial, Bazureau, Jean-Pierre, Villalgordo, Jose Manuel
Publicado 2015

Synthesis of New N,N’-Bis(5-arylidene-4-oxo-4,5-dihydrothiazolin-2-yl)piperazine Derivatives Under Microwave Irradiation and Preliminary Biological Evaluation

por Coulibaly, Wacothon Karime, Paquin, Ludovic, Bénié, Anoubilé, Bekro, Yves-Alain, Durieux, Emilie, Meijer, Laurent, Le Guével, Rémy, Corlu, Anne, Bazureau, Jean-Pierre
Publicado 2012

Design and Microwave Synthesis of New (5Z) 5-Arylidene-2-thioxo-1,3-thiazolinidin-4-one and (5Z) 2-Amino-5-arylidene-1,3-thiazol-4(5H)-one as New Inhibitors of Protein Kinase DYRK1...

por Bourahla, Khadidja, Guihéneuf, Solène, Limanton, Emmanuelle, Paquin, Ludovic, Le Guével, Rémy, Charlier, Thierry, Rahmouni, Mustapha, Durieu, Emilie, Lozach, Olivier, Carreaux, François, Meijer, Laurent, Bazureau, Jean-Pierre
Publicado 2021

Synthetic Development of New 3-(4-Arylmethylamino)butyl-5-arylidene-rhodanines under Microwave Irradiation and Their Effects on Tumor Cell Lines and against Protein Kinases

por Dago, Camille Déliko, Ambeu, Christelle N´ta, Coulibaly, Wacothon-Karime, Békro, Yves-Alain, Mamyrbékova, Janat, Defontaine, Audrey, Baratte, Blandine, Bach, Stéphane, Ruchaud, Sandrine, Le Guével, Rémy, Ravache, Myriam, Corlu, Anne, Bazureau, Jean-Pierre
Publicado 2015

Correction of cognitive deficits in mouse models of Down syndrome by a pharmacological inhibitor of DYRK1A

por Nguyen, Thu Lan, Duchon, Arnaud, Manousopoulou, Antigoni, Loaëc, Nadège, Villiers, Benoît, Pani, Guillaume, Karatas, Meltem, Mechling, Anna E., Harsan, Laura-Adela, Limanton, Emmanuelle, Bazureau, Jean-Pierre, Carreaux, François, Garbis, Spiros D., Meijer, Laurent, Herault, Yann
Publicado 2018

Marine-Derived 2-Aminoimidazolone Alkaloids. Leucettamine B-Related Polyandrocarpamines Inhibit Mammalian and Protozoan DYRK & CLK Kinases

por Loaëc, Nadège, Attanasio, Eletta, Villiers, Benoît, Durieu, Emilie, Tahtouh, Tania, Cam, Morgane, Davis, Rohan A., Alencar, Aline, Roué, Mélanie, Bourguet-Kondracki, Marie-Lise, Proksch, Peter, Limanton, Emmanuelle, Guiheneuf, Solène, Carreaux, François, Bazureau, Jean-Pierre, Klautau, Michelle, Meijer, Laurent
Publicado 2017

Inhibition of DYRK1A proteolysis modifies its kinase specificity and rescues Alzheimer phenotype in APP/PS1 mice

por Souchet, Benoît, Audrain, Mickael, Billard, Jean Marie, Dairou, Julien, Fol, Romain, Orefice, Nicola Salvatore, Tada, Satoru, Gu, Yuchen, Dufayet-Chaffaud, Gaelle, Limanton, Emmanuelle, Carreaux, François, Bazureau, Jean-Pierre, Alves, Sandro, Meijer, Laurent, Janel, Nathalie, Braudeau, Jérôme, Cartier, Nathalie
Publicado 2019