Mitochondrial mechanisms and therapeutics in ischaemia reperfusion injury

por Martin, Jack L., Gruszczyk, Anja V., Beach, Timothy E., Murphy, Michael P., Saeb-Parsy, Kourosh
Publicado 2018

Selective Delivery of Dicarboxylates to Mitochondria by Conjugation to a Lipophilic Cation via a Cleavable Linker

por Prag, Hiran A., Kula-Alwar, Duvaraka, Pala, Laura, Caldwell, Stuart T., Beach, Timothy E., James, Andrew M., Saeb-Parsy, Kourosh, Krieg, Thomas, Hartley, Richard C., Murphy, Michael P.
Publicado 2020

Targeting succinate dehydrogenase with malonate ester prodrugs decreases renal ischemia reperfusion injury

por Beach, Timothy E., Prag, Hiran A., Pala, Laura, Logan, Angela, Huang, Margaret M., Gruszczyk, Anja V., Martin, Jack L., Mahbubani, Krishnaa, Hamed, Mazin O., Hosgood, Sarah A., Nicholson, Michael L., James, Andrew M., Hartley, Richard C., Murphy, Michael P., Saeb-Parsy, Kourosh
Publicado 2020

Mechanism of succinate efflux upon reperfusion of the ischaemic heart

por Prag, Hiran A, Gruszczyk, Anja V, Huang, Margaret M, Beach, Timothy E, Young, Timothy, Tronci, Laura, Nikitopoulou, Efterpi, Mulvey, John F, Ascione, Raimondo, Hadjihambi, Anna, Shattock, Michael J, Pellerin, Luc, Saeb-Parsy, Kourosh, Frezza, Christian, James, Andrew M, Krieg, Thomas, Murphy, Michael P, Aksentijević, Dunja
Publicado 2020

Ester Prodrugs of Malonate with Enhanced Intracellular Delivery Protect Against Cardiac Ischemia-Reperfusion Injury In Vivo

por Prag, Hiran A., Pala, Laura, Kula-Alwar, Duvaraka, Mulvey, John F., Luping, Du, Beach, Timothy E., Booty, Lee M., Hall, Andrew R., Logan, Angela, Sauchanka, Volha, Caldwell, Stuart T., Robb, Ellen L., James, Andrew M., Xu, Zhelong, Saeb-Parsy, Kourosh, Hartley, Richard C., Murphy, Michael P., Krieg, Thomas
Publicado 2020

Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation

por Martin, Jack L., Costa, Ana S. H., Gruszczyk, Anja V., Beach, Timothy E., Allen, Fay M., Prag, Hiran A., Hinchy, Elizabeth C., Mahbubani, Krishnaa, Hamed, Mazin, Tronci, Laura, Nikitopoulou, Efterpi, James, Andrew M., Krieg, Thomas, Robinson, Alan J., Huang, Margaret H., Caldwell, Stuart T., Logan, Angela, Pala, Laura, Hartley, Richard C., Frezza, Christian, Saeb-Parsy, Kourosh, Murphy, Michael P.
Publicado 2019