Evaluation of drug-drug interaction between rilpivirine and rifapentine using PBPK modelling

por Grañana-Castillo, Sandra, Montanha, Maiara Camotti, Bearon, Rachel, Khoo, Saye, Siccardi, Marco
Publicado 2022

Transport of Fibroblast Growth Factor 2 in the Pericellular Matrix Is Controlled by the Spatial Distribution of Its Binding Sites in Heparan Sulfate

por Duchesne, Laurence, Octeau, Vivien, Bearon, Rachel N., Beckett, Alison, Prior, Ian A., Lounis, Brahim, Fernig, David G.
Publicado 2012

Tight Control of Hypoxia-inducible Factor-α Transient Dynamics Is Essential for Cell Survival in Hypoxia

por Bagnall, James, Leedale, Joseph, Taylor, Sarah E., Spiller, David G., White, Michael R. H., Sharkey, Kieran J., Bearon, Rachel N., Sée, Violaine
Publicado 2014

Multiscale modelling of drug transport and metabolism in liver spheroids

por Leedale, Joseph A., Kyffin, Jonathan A., Harding, Amy L., Colley, Helen E., Murdoch, Craig, Sharma, Parveen, Williams, Dominic P., Webb, Steven D., Bearon, Rachel N.
Publicado 2020

Actin filaments form a size‐dependent diffusion barrier around centrosomes

por Cheng, Hsuan, Kao, Yu‐Lin, Chen, Ting, Sharma, Lohitaksh, Yang, Wen‐Ting, Chuang, Yi‐Chien, Huang, Shih‐Han, Lin, Hong‐Rui, Huang, Yao‐Shen, Kao, Chi‐Ling, Yang, Lee‐Wei, Bearon, Rachel, Cheng, Hui‐Chun, Hsia, Kuo‐Chiang, Lin, Yu‐Chun
Publicado 2022

Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms

por Pridgeon, Chris S., Schlott, Constanze, Wong, Min Wei, Heringa, Minne B., Heckel, Tobias, Leedale, Joe, Launay, Laurence, Gryshkova, Vitalina, Przyborski, Stefan, Bearon, Rachel N., Wilkinson, Emma L., Ansari, Tahera, Greenman, John, Hendriks, Delilah F. G., Gibbs, Sue, Sidaway, James, Sison-Young, Rowena L., Walker, Paul, Cross, Mike J., Park, B. Kevin, Goldring, Chris E. P.
Publicado 2018