The c-Met receptor tyrosine kinase inhibitor MP470 radiosensitizes glioblastoma cells

por Welsh, James W, Mahadevan, Daruka, Ellsworth, Ron, Cooke, Laurence, Bearss, David, Stea, Baldassarre
Publicado 2009

Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma

por Sankar, Savita, Bell, Russell, Stephens, Bret, Zhuo, Rupeng, Sharma, Sunil, Bearss, David J., Lessnick, Stephen L.
Publicado 2012

MP470, a novel receptor tyrosine kinase inhibitor, in combination with Erlotinib inhibits the HER family/PI3K/Akt pathway and tumor growth in prostate cancer

por Qi, Wenqing, Cooke, Larry S, Stejskal, Amy, Riley, Christopher, Croce, Kimiko Della, Saldanha, Jose W, Bearss, David, Mahadevan, Daruka
Publicado 2009

Inhibition of Nek2 by Small Molecules Affects Proteasome Activity

por Meng, Lingyao, Carpenter, Kent, Mollard, Alexis, Vankayalapati, Hariprasad, Warner, Steven L., Sharma, Sunil, Tricot, Guido, Zhan, Fenghuang, Bearss, David J.
Publicado 2014

Highly effective combination of LSD1 (KDM1A) antagonist and pan-histone deacetylase inhibitor against human AML cells

por Fiskus, Warren, Sharma, Sunil, Shah, Bhavin, Portier, Bryce P., Devaraj, Santhana G. T., Liu, Ka, Iyer, Swaminathan P., Bearss, David, Bhalla, Kapil N.
Publicado 2014

Phenotypic chemical screening using a zebrafish neural crest EMT reporter identifies retinoic acid as an inhibitor of epithelial morphogenesis

por Jimenez, Laura, Wang, Jindong, Morrison, Monique A., Whatcott, Clifford, Soh, Katherine K., Warner, Steven, Bearss, David, Jette, Cicely A., Stewart, Rodney A.
Publicado 2016

S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis)

por Lavelle, Donald, Saunthararajah, Yogen, Vaitkus, Kestis, Singh, Mahipal, Banzon, Virryan, Phiasivongsva, Pasit, Redkar, Sanjeev, Kanekal, Sarath, Bearss, David, Shi, Chongtie, Inloes, Roger, DeSimone, Joseph
Publicado 2010

Chemical Genetic Screen Reveals a Role for Desmosomal Adhesion in Mammary Branching Morphogenesis

por Basham, Kaitlin J., Kieffer, Collin, Shelton, Dawne N., Leonard, Christopher J., Bhonde, Vasudev R., Vankayalapati, Hariprasad, Milash, Brett, Bearss, David J., Looper, Ryan E., Welm, Bryan E.
Publicado 2013

Upregulation of AXL and β-catenin in chronic lymphocytic leukemia cells cultured with bone marrow stroma cells is associated with enhanced drug resistance

por Sinha, Sutapa, Secreto, Charla R., Boysen, Justin C., Lesnick, Connie, Wang, Zhiquan, Ding, Wei, Call, Timothy G., Kenderian, Saad J., Parikh, Sameer A., Warner, Steven L., Bearss, David J., Ghosh, Asish K., Kay, Neil E.
Publicado 2021

Combined venetoclax and alvocidib in acute myeloid leukemia

por Bogenberger, James, Whatcott, Clifford, Hansen, Nanna, Delman, Devora, Shi, Chang-Xin, Kim, Wontak, Haws, Hillary, Soh, Katherine, Lee, Ye Sol, Peterson, Peter, Siddiqui-Jain, Adam, Weitman, Steven, Stewart, Keith, Bearss, David, Mesa, Ruben, Warner, Steven, Tibes, Raoul
Publicado 2017

Use of a Bacteriophage Lysin to Identify a Novel Target for Antimicrobial Development

por Schuch, Raymond, Pelzek, Adam J., Raz, Assaf, Euler, Chad W., Ryan, Patricia A., Winer, Benjamin Y., Farnsworth, Andrew, Bhaskaran, Shyam S., Stebbins, C. Erec, Xu, Yong, Clifford, Adrienne, Bearss, David J., Vankayalapati, Hariprasad, Goldberg, Allan R., Fischetti, Vincent A.
Publicado 2013

Mitochondrial Priming of Chronic Lymphocytic Leukemia Patients Associates Bcl-x(L) Dependence with Alvocidib Response

por Pierceall, William E., Warner, Steven L., Lena, Ryan J., Doykan, Camille, Blake, Noel, Elashoff, Michael, Von Hoff, Daniel, Bearss, David J., Cardone, Michael H., Andritsos, Leslie, Byrd, John C., Lanasa, Mark C., Grever, Michael R., Johnson, Amy J.
Publicado 2014

Chronic lymphocytic leukemia cells from ibrutinib treated patients are sensitive to Axl receptor tyrosine kinase inhibitor therapy

por Sinha, Sutapa, Boysen, Justin C., Chaffee, Kari G., Kabat, Brian F., Slager, Susan L., Parikh, Sameer A., Secreto, Charla R., Call, Tim, Shanafelt, Tait D., Leis, Jose F., Warner, Steven L., Bearss, David J., Ghosh, Asish K., Kay, Neil E.
Publicado 2018

A Small-Molecule Inhibitor of PIM Kinases as a Potential Treatment for Urothelial Carcinomas()()

por Foulks, Jason M., Carpenter, Kent J., Luo, Bai, Xu, Yong, Senina, Anna, Nix, Rebecca, Chan, Ashley, Clifford, Adrianne, Wilkes, Marcus, Vollmer, David, Brenning, Benjamin, Merx, Shannon, Lai, Shuping, McCullar, Michael V., Ho, Koc-Kan, Albertson, Daniel J., Call, Lee T., Bearss, Jared J., Tripp, Sheryl, Liu, Ting, Stephens, Bret J., Mollard, Alexis, Warner, Steven L., Bearss, David J., Kanner, Steven B.
Publicado 2014

A prospective biomarker analysis of alvocidib followed by cytarabine and mitoxantrone in MCL-1-dependent relapsed/refractory acute myeloid leukemia

por Zeidner, Joshua F., Lin, Tara L., Vigil, Carlos E., Fine, Gil, Yair Levy, M., Nazha, Aziz, Esteve, Jordi, Lee, Daniel J., Yee, Karen, Dalovisio, Andrew, Wang, Eunice S., Bergua Burgues, Juan M., Schriber, Jeffrey, Litzow, Mark R., Frankfurt, Olga, Castillo, Teresa Bernal Del, Bhatt, Vijaya Raj, Bhatnagar, Bhavana, Mehta, Priyanka, Dillon, Richard, Vicente, Maria Vidriales, Anthony, Stephen, Bearss, David, Montesinos, Pau, Douglas Smith, B.
Publicado 2021

TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth

por Chan, Tsz-Yin, Egbert, Christina M., Maxson, Julia E., Siddiqui, Adam, Larsen, Logan J., Kohler, Kristina, Balasooriya, Eranga Roshan, Pennington, Katie L., Tsang, Tsz-Ming, Frey, Madison, Soderblom, Erik J., Geng, Huimin, Müschen, Markus, Forostyan, Tetyana V., Free, Savannah, Mercenne, Gaelle, Banks, Courtney J., Valdoz, Jonard, Whatcott, Clifford J., Foulks, Jason M., Bearss, David J., O’Hare, Thomas, Huang, David C. S., Christensen, Kenneth A., Moody, James, Warner, Steven L., Tyner, Jeffrey W., Andersen, Joshua L.
Publicado 2021