How Can Genetic Studies Help Us to Understand Links Between Birth Weight and Type 2 Diabetes?

por Beaumont, Robin N., Horikoshi, Momoko, McCarthy, Mark I., Freathy, Rachel M.
Publicado 2017

The Effect of Genetic Variation on the Placental Transcriptome in Humans

por Kikas, Triin, Rull, Kristiina, Beaumont, Robin N., Freathy, Rachel M., Laan, Maris
Publicado 2019

Common genetic variants with fetal effects on birth weight are enriched for proximity to genes implicated in rare developmental disorders

por Beaumont, Robin N, Mayne, Isabelle K, Freathy, Rachel M, Wright, Caroline F
Publicado 2021

Does Obesity Cause Thyroid Cancer? A Mendelian Randomization Study

por Fussey, Jonathan Mark, Beaumont, Robin N, Wood, Andrew R, Vaidya, Bijay, Smith, Joel, Tyrrell, Jessica
Publicado 2020

Mendelian randomization supports a causative effect of TSH on thyroid carcinoma

por Fussey, Jonathan M, Beaumont, Robin N, Wood, Andrew R, Vaidya, Bijay, Smith, Joel, Tyrrell, Jessica
Publicado 2020

RETRACTION: Mendelian randomization supports a causative effect of TSH on thyroid carcinoma

por Fussey, Jonathan M, Beaumont, Robin N, Wood, Andrew R, Vaidya, Bijay, Smith, Joel, Tyrrell, Jessica
Publicado 2020

Rare genetic variants in genes and loci linked to dominant monogenic developmental disorders cause milder related phenotypes in the general population

por Kingdom, Rebecca, Tuke, Marcus, Wood, Andrew, Beaumont, Robin N., Frayling, Timothy M., Weedon, Michael N., Wright, Caroline F.
Publicado 2022

Assessing whether genetic scores explain extra variation in birthweight, when added to clinical and anthropometric measures

por Haulder, Maneka, Hughes, Alice E., Beaumont, Robin N., Knight, Bridget A., Hattersley, Andrew T., Shields, Beverley M., Freathy, Rachel M.
Publicado 2022

Identification and analysis of individuals who deviate from their genetically-predicted phenotype

por Hawkes, Gareth, Yengo, Loic, Vedantam, Sailaja, Marouli, Eirini, Beaumont, Robin N., Tyrrell, Jessica, Weedon, Michael N., Hirschhorn, Joel, Frayling, Timothy M., Wood, Andrew R.
Publicado 2023

A genome-wide association study identifies 5 loci associated with frozen shoulder and implicates diabetes as a causal risk factor

por Green, Harry D., Jones, Alistair, Evans, Jonathan P., Wood, Andrew R., Beaumont, Robin N., Tyrrell, Jessica, Frayling, Timothy M., Smith, Christopher, Weedon, Michael N.
Publicado 2021

Investigating a possible causal relationship between maternal serum urate concentrations and offspring birthweight: a Mendelian randomization study

por Decina, Caitlin S, Hopkins, Rhian, Bowden, Jack, Shields, Beverly M, Lawlor, Deborah A, Warrington, Nicole M, Evans, David M, Freathy, Rachel M, Beaumont, Robin N
Publicado 2022

Identification and analysis of individuals who deviate from their genetically-predicted phenotype

por Hawkes, Gareth, Yengo, Loic, Vedantam, Sailaja, Marouli, Eirini, Beaumont, Robin N, Tyrrell, Jessica, Weedon, Michael N, Hirschhorn, Joel, Frayling, Timothy M, Wood, Andrew R
Publicado 2023

Direct and INdirect effects analysis of Genetic lOci (DINGO): A software package to increase the power of locus discovery in GWAS meta-analyses of perinatal phenotypes and traits i...

por Hwang, Liang-Dar, Cuellar-Partida, Gabriel, Yengo, Loic, Zeng, Jian, Beaumont, Robin N., Freathy, Rachel M., Moen, Gunn-Helen, Warrington, Nicole M., Evans, David M.
Publicado 2023

Investigating the causal effect of maternal vitamin B12 and folate levels on offspring birthweight

por Moen, Gunn-Helen, Beaumont, Robin N, Grarup, Niels, Sommer, Christine, Shields, Beverley M, Lawlor, Deborah A, Freathy, Rachel M, Evans, David M, Warrington, Nicole M
Publicado 2020

Association of maternal circulating 25(OH)D and calcium with birth weight: A mendelian randomisation analysis

por Thompson, William D., Tyrrell, Jessica, Borges, Maria-Carolina, Beaumont, Robin N., Knight, Bridget A., Wood, Andrew R., Ring, Susan M., Hattersley, Andrew T., Freathy, Rachel M., Lawlor, Debbie A.
Publicado 2019

A genome-wide association study implicates multiple mechanisms influencing raised urinary albumin–creatinine ratio

por Casanova, Francesco, Tyrrell, Jessica, Beaumont, Robin N, Ji, Yingjie, Jones, Samuel E, Hattersley, Andrew T, Weedon, Michael N, Murray, Anna, Shore, Angela C, Frayling, Timothy M, Wood, Andrew R
Publicado 2019

Genetically proxied therapeutic prolyl-hydroxylase inhibition and cardiovascular risk

por Harlow, Charli E, Patel, Vickas V, Waterworth, Dawn M, Wood, Andrew R, Beaumont, Robin N, Ruth, Katherine S, Tyrrell, Jessica, Oguro-Ando, Asami, Chu, Audrey Y, Frayling, Timothy M
Publicado 2022

Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause and impact female reproductive health

por Ruth, Katherine S., Beaumont, Robin N., Tyrrell, Jessica, Jones, Samuel E., Tuke, Marcus A., Yaghootkar, Hanieh, Wood, Andrew R., Freathy, Rachel M., Weedon, Michael N., Frayling, Timothy M., Murray, Anna
Publicado 2016

Higher adiposity and mental health: causal inference using Mendelian randomization

por Casanova, Francesco, O’Loughlin, Jessica, Martin, Susan, Beaumont, Robin N, Wood, Andrew R, Watkins, Edward R, Freathy, Rachel M, Hagenaars, Saskia P, Frayling, Timothy M, Yaghootkar, Hanieh, Tyrrell, Jess
Publicado 2021

Recurrent 17q12 microduplications contribute to renal disease but not diabetes

por Cannon, Stuart, Clissold, Rhian, Sukcharoen, Kittiya, Tuke, Marcus, Hawkes, Gareth, Beaumont, Robin N, Wood, Andrew R, Gilchrist, Mark, Hattersley, Andrew T, Oram, Richard A, Patel, Kashyap, Wright, Caroline, Weedon, Michael N
Publicado 2023