Hyperexcitability in young iPSC-derived C9ORF72 mutant motor neurons is associated with increased intracellular calcium release

por Burley, Sarah, Beccano-Kelly, Dayne A., Talbot, Kevin, Llana, Oscar Cordero, Wade-Martins, Richard
Publicado 2022

From Synaptic Dysfunction to Neuroprotective Strategies in Genetic Parkinson’s Disease: Lessons From LRRK2

por Mancini, Andrea, Mazzocchetti, Petra, Sciaccaluga, Miriam, Megaro, Alfredo, Bellingacci, Laura, Beccano-Kelly, Dayne A., Di Filippo, Massimiliano, Tozzi, Alessandro, Calabresi, Paolo
Publicado 2020

Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice

por Beccano-Kelly, Dayne A., Kuhlmann, Naila, Tatarnikov, Igor, Volta, Mattia, Munsie, Lise N., Chou, Patrick, Cao, Li-Ping, Han, Heather, Tapia, Lucia, Farrer, Matthew J., Milnerwood, Austen J.
Publicado 2014

Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson’s iPSC-dopamine neurons

por Beccano-Kelly, Dayne A., Cherubini, Marta, Mousba, Yassine, Cramb, Kaitlyn M.L., Giussani, Stefania, Caiazza, Maria Claudia, Rai, Pavandeep, Vingill, Siv, Bengoa-Vergniory, Nora, Ng, Bryan, Corda, Gabriele, Banerjee, Abhirup, Vowles, Jane, Cowley, Sally, Wade-Martins, Richard
Publicado 2023

Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice

por Volta, Mattia, Beccano-Kelly, Dayne A, Paschall, Sarah A, Cataldi, Stefano, MacIsaac, Sarah E, Kuhlmann, Naila, Kadgien, Chelsie A, Tatarnikov, Igor, Fox, Jesse, Khinda, Jaskaran, Mitchell, Emma, Bergeron, Sabrina, Melrose, Heather, Farrer, Matthew J, Milnerwood, Austen J
Publicado 2017