Pharmacophore Models and Pharmacophore-Based Virtual Screening: Concepts and Applications Exemplified on Hydroxysteroid Dehydrogenases

por Kaserer, Teresa, Beck, Katharina R., Akram, Muhammad, Odermatt, Alex, Schuster, Daniela
Publicado 2015

Posaconazole-Induced Hypertension Due to Inhibition of 11β-Hydroxylase and 11β-Hydroxysteroid Dehydrogenase 2

por Thompson, George R, Beck, Katharina R, Patt, Melanie, Kratschmar, Denise V, Odermatt, Alex
Publicado 2019

11β-Hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor γ

por Beck, Katharina R., Inderbinen, Silvia G., Kanagaratnam, Sharavan, Kratschmar, Denise V., Jetten, Anton M., Yamaguchi, Hideaki, Odermatt, Alex
Publicado 2019

Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice

por Bell, Rachel M.B., Villalobos, Elisa, Nixon, Mark, Miguelez-Crespo, Allende, Murphy, Lee, Fawkes, Angie, Coutts, Audrey, Sharp, Matthew G.F., Koerner, Martha V., Allan, Emma, Meijer, Onno C., Houtman, Renè, Odermatt, Alex, Beck, Katharina R., Denham, Scott G., Lee, Patricia, Homer, Natalie Z.M., Walker, Brian R., Morgan, Ruth A.
Publicado 2021

Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity

por Morgan, Ruth A., Beck, Katharina R., Nixon, Mark, Homer, Natalie Z. M., Crawford, Andrew A., Melchers, Diana, Houtman, René, Meijer, Onno C., Stomby, Andreas, Anderson, Anna J., Upreti, Rita, Stimson, Roland H., Olsson, Tommy, Michoel, Tom, Cohain, Ariella, Ruusalepp, Arno, Schadt, Eric E., Björkegren, Johan L. M., Andrew, Ruth, Kenyon, Christopher J., Hadoke, Patrick W. F., Odermatt, Alex, Keen, John A., Walker, Brian R.
Publicado 2017