Mathematical Modelling Based on In Vivo Imaging Suggests CD137-Stimulated Cytotoxic T Lymphocytes Exert Superior Tumour Control Due to an Enhanced Antimitotic Effect on Tumour Cell...

por Beck, Richard J., Weigelin, Bettina, Beltman, Joost B.
Publicado 2021

Heterogeneous, delayed-onset killing by multiple-hitting T cells: Stochastic simulations to assess methods for analysis of imaging data

por Beck, Richard J., Bijker, Dario I., Beltman, Joost B.
Publicado 2020

Mathematical modeling identifies LAG3 and HAVCR2 as biomarkers of T cell exhaustion in melanoma

por Beck, Richard J., Sloot, Sander, Matsushita, Hirokazu, Kakimi, Kazuhiro, Beltman, Joost B.
Publicado 2023

Intra-tumor heterogeneity, turnover rate and karyotype space shape susceptibility to missegregation-induced extinction

por Kimmel, Gregory J., Beck, Richard J., Yu, Xiaoqing, Veith, Thomas, Bakhoum, Samuel, Altrock, Philipp M., Andor, Noemi
Publicado 2023

Single-cell imaging of CAR T cell activity in vivo reveals extensive functional and anatomical heterogeneity

por Cazaux, Marine, Grandjean, Capucine L., Lemaître, Fabrice, Garcia, Zacarias, Beck, Richard J., Milo, Idan, Postat, Jérémy, Beltman, Joost B., Cheadle, Eleanor J., Bousso, Philippe
Publicado 2019