The Moonwalker Mouse: New Insights into TRPC3 Function, Cerebellar Development, and Ataxia

por Becker, Esther B. E.
Publicado 2014

Modulation and Regulation of Canonical Transient Receptor Potential 3 (TRPC3) Channels

por Cole, Bethan A., Becker, Esther B. E.
Publicado 2023

The Use of Stem Cell-Derived Neurons for Understanding Development and Disease of the Cerebellum

por Nayler, Samuel P., Becker, Esther B. E.
Publicado 2018

Purkinje Cell Patterning—Insights from Single-Cell Sequencing

por Apsley, Elizabeth J., Becker, Esther B. E.
Publicado 2022

Modeling Suggests TRPC3 Hydrogen Bonding and Not Phosphorylation Contributes to the Ataxia Phenotype of the Moonwalker Mouse

por Hanson, Sonya M., Sansom, Mark S. P., Becker, Esther B. E.
Publicado 2015

Induced pluripotent stem cell technology for modelling and therapy of cerebellar ataxia

por Watson, Lauren M., Wong, Maggie M. K., Becker, Esther B. E.
Publicado 2015

Recent advances in modelling of cerebellar ataxia using induced pluripotent stem cells

por Wong, Maggie M. K., Watson, Lauren M., Becker, Esther B. E.
Publicado 2017

Deconstructing cerebellar development cell by cell

por van Essen, Max J., Nayler, Samuel, Becker, Esther B. E., Jacob, John
Publicado 2020

High-resolution transcriptional landscape of xeno-free human induced pluripotent stem cell-derived cerebellar organoids

por Nayler, Samuel, Agarwal, Devika, Curion, Fabiola, Bowden, Rory, Becker, Esther B. E.
Publicado 2021

A gene expression signature in developing Purkinje cells predicts autism and intellectual disability co-morbidity status

por Clifford, Harry, Dulneva, Anna, Ponting, Chris P., Haerty, Wilfried, Becker, Esther B. E.
Publicado 2019

A Simplified Method for Generating Purkinje Cells from Human-Induced Pluripotent Stem Cells

por Watson, Lauren M., Wong, Maggie M. K., Vowles, Jane, Cowley, Sally A., Becker, Esther B. E.
Publicado 2018

The mutant Moonwalker TRPC3 channel links calcium signaling to lipid metabolism in the developing cerebellum

por Dulneva, Anna, Lee, Sheena, Oliver, Peter L., Di Gleria, Katalin, Kessler, Benedikt M., Davies, Kay E., Becker, Esther B. E.
Publicado 2015

Caspr2 interacts with type 1 inositol 1,4,5-trisphosphate receptor in the developing cerebellum and regulates Purkinje cell morphology

por Argent, Liam, Winter, Friederike, Prickett, Imogen, Carrasquero-Ordaz, Maria, Olsen, Abby L., Kramer, Holger, Lancaster, Eric, Becker, Esther B. E.
Publicado 2020

Candidate Screening of the TRPC3 Gene in Cerebellar Ataxia

por Becker, Esther B. E., Fogel, Brent L., Rajakulendran, Sanjeev, Dulneva, Anna, Hanna, Michael G., Perlman, Susan L., Geschwind, Daniel H., Davies, Kay E.
Publicado 2011

Oxr1 Is Essential for Protection against Oxidative Stress-Induced Neurodegeneration

por Oliver, Peter L., Finelli, Mattéa J., Edwards, Benjamin, Bitoun, Emmanuelle, Butts, Darcy L., Becker, Esther B. E., Cheeseman, Michael T., Davies, Ben, Davies, Kay E.
Publicado 2011

Functional expression of calcium‐permeable canonical transient receptor potential 4‐containing channels promotes migration of medulloblastoma cells

por Wei, Wei‐Chun, Huang, Wan‐Chen, Lin, Yu‐Ping, Becker, Esther B. E., Ansorge, Olaf, Flockerzi, Veit, Conti, Daniele, Cenacchi, Giovanna, Glitsch, Maike D.
Publicado 2017

Contactin-associated protein-2 antibodies in non-paraneoplastic cerebellar ataxia

por Becker, Esther B E, Zuliani, Luigi, Pettingill, Rosemary, Lang, Bethan, Waters, Patrick, Dulneva, Anna, Sobott, Frank, Wardle, Mark, Graus, Francesc, Bataller, Luis, Robertson, Neil P, Vincent, Angela
Publicado 2012

A Transient Translaminar GABAergic Interneuron Circuit Connects Thalamocortical Recipient Layers in Neonatal Somatosensory Cortex

por Marques-Smith, Andre, Lyngholm, Daniel, Kaufmann, Anna-Kristin, Stacey, Jacqueline A., Hoerder-Suabedissen, Anna, Becker, Esther B.E., Wilson, Michael C., Molnár, Zoltán, Butt, Simon J.B.
Publicado 2016

Neurodegeneration in SCA14 is associated with increased PKCγ kinase activity, mislocalization and aggregation

por Wong, Maggie M. K., Hoekstra, Stephanie D., Vowles, Jane, Watson, Lauren M., Fuller, Geraint, Németh, Andrea H., Cowley, Sally A., Ansorge, Olaf, Talbot, Kevin, Becker, Esther B. E.
Publicado 2018

Dominant Mutations in GRM1 Cause Spinocerebellar Ataxia Type 44

por Watson, Lauren M., Bamber, Elizabeth, Schnekenberg, Ricardo Parolin, Williams, Jonathan, Bettencourt, Conceição, Lickiss, Jennifer, Fawcett, Katherine, Clokie, Samuel, Wallis, Yvonne, Clouston, Penny, Sims, David, Houlden, Henry, Becker, Esther B.E., Németh, Andrea H.
Publicado 2017