The metalloproteases meprin α and meprin β: unique enzymes in inflammation, neurodegeneration, cancer and fibrosis

por Broder, Claudia, Becker-Pauly, Christoph
Publicado 2013

TNFα cleavage beyond TACE/ADAM17: matrix metalloproteinase 13 is a potential therapeutic target in sepsis and colitis

por Becker-Pauly, Christoph, Rose-John, Stefan
Publicado 2013

Mice are not Men: ADAM30 Findings Emphasize a Broader Look Towards Murine Alzheimer's Disease Models

por Becker-Pauly, Christoph, Pietrzik, Claus U.
Publicado 2016

The Metalloprotease Meprin β Is an Alternative β-Secretase of APP

por Becker-Pauly, Christoph, Pietrzik, Claus U.
Publicado 2017

Let It Flow: Morpholino Knockdown in Zebrafish Embryos Reveals a Pro-Angiogenic Effect of the Metalloprotease Meprin α(2)

por Schütte, André, Hedrich, Jana, Stöcker, Walter, Becker-Pauly, Christoph
Publicado 2010

Evaluation of (¹¹¹)In-Labelled Exendin-4 Derivatives Containing Different Meprin β-Specific Cleavable Linkers

por Jodal, Andreas, Pape, Fabienne, Becker-Pauly, Christoph, Maas, Ole, Schibli, Roger, Béhé, Martin
Publicado 2015

The putative pleiotropic functions of meprin β in gastric cancer

por Siemsen, Wiebke, Halske, Christine, Behrens, Hans-Michael, Krüger, Sandra, Becker-Pauly, Christoph, Röcken, Christoph
Publicado 2023

Zymogenic latency in an ∼250-million-year-old astacin metallopeptidase

por Guevara, Tibisay, Rodríguez-Banqueri, Arturo, Stöcker, Walter, Becker-Pauly, Christoph, Gomis-Rüth, F. Xavier
Publicado 2022

Distinct contributions of meprins to skin regeneration after injury – Meprin α a physiological processer of pro-collagen VII

por Kruppa, Daniel, Peters, Florian, Bornert, Olivier, Maler, Mareike D., Martin, Stefan F., Becker-Pauly, Christoph, Nyström, Alexander
Publicado 2021

Differences in Shedding of the Interleukin-11 Receptor by the Proteases ADAM9, ADAM10, ADAM17, Meprin α, Meprin β and MT1-MMP

por Sammel, Martin, Peters, Florian, Lokau, Juliane, Scharfenberg, Franka, Werny, Ludwig, Linder, Stefan, Garbers, Christoph, Rose-John, Stefan, Becker-Pauly, Christoph
Publicado 2019

Joint Reconstituted Signaling of the IL-6 Receptor via Extracellular Vesicles

por Arnold, Philipp, Lückstädt, Wiebke, Li, Wenjia, Boll, Inga, Lokau, Juliane, Garbers, Christoph, Lucius, Ralph, Rose-John, Stefan, Becker-Pauly, Christoph
Publicado 2020

PCSK9 acts as a key regulator of Aβ clearance across the blood–brain barrier

por Mazura, Alexander D., Ohler, Anke, Storck, Steffen E., Kurtyka, Magdalena, Scharfenberg, Franka, Weggen, Sascha, Becker-Pauly, Christoph, Pietrzik, Claus U.
Publicado 2022

Cell Surface Processing of CD109 by Meprin β Leads to the Release of Soluble Fragments and Reduced Expression on Extracellular Vesicles

por Lückstädt, Wiebke, Bub, Simon, Koudelka, Tomas, Pavlenko, Egor, Peters, Florian, Somasundaram, Prasath, Becker-Pauly, Christoph, Lucius, Ralph, Zunke, Friederike, Arnold, Philipp
Publicado 2021

Proteolysis of CD44 at the cell surface controls a downstream protease network

por Wöhner, Birte, Li, Wenjia, Hey, Sven, Drobny, Alice, Werny, Ludwig, Becker-Pauly, Christoph, Lucius, Ralph, Zunke, Friederike, Linder, Stefan, Arnold, Philipp
Publicado 2023

Metalloproteinase meprin α regulates migration and invasion of human hepatocarcinoma cells and is a mediator of the oncoprotein Reptin

por Breig, Osman, Yates, Maïlyn, Neaud, Véronique, Couchy, Gabrielle, Grigoletto, Aude, Lucchesi, Carlo, Prox, Johannes, Zucman-Rossi, Jessica, Becker-Pauly, Christoph, Rosenbaum, Jean
Publicado 2016

Inhibitors of BMP‐1/tolloid‐like proteinases: efficacy, selectivity and cellular toxicity

por Talantikite, Maya, Lécorché, Pascaline, Beau, Fabrice, Damour, Odile, Becker‐Pauly, Christoph, Ho, Wen‐Bin, Dive, Vincent, Vadon‐Le Goff, Sandrine, Moali, Catherine
Publicado 2018

Discovery and Optimization of Selective Inhibitors of Meprin α (Part I)

por Hou, Shurong, Diez, Juan, Wang, Chao, Becker-Pauly, Christoph, Fields, Gregg B., Bannister, Thomas, Spicer, Timothy P., Scampavia, Louis D., Minond, Dmitriy
Publicado 2021

Metalloprotease Meprinβ in Rat Kidney: Glomerular Localization and Differential Expression in Glomerulonephritis

por Oneda, Beatrice, Lods, Nadège, Lottaz, Daniel, Becker-Pauly, Christoph, Stöcker, Walter, Pippin, Jeffrey, Huguenin, Maya, Ambort, Daniel, Marti, Hans-Peter, Sterchi, Erwin E.
Publicado 2008

Discovery and Optimization of Selective Inhibitors of Meprin α (Part II)

por Wang, Chao, Diez, Juan, Park, Hajeung, Becker-Pauly, Christoph, Fields, Gregg B., Spicer, Timothy P., Scampavia, Louis D., Minond, Dmitriy, Bannister, Thomas D.
Publicado 2021

Proteomic Analyses Reveal an Acidic Prime Side Specificity for the Astacin Metalloprotease Family Reflected by Physiological Substrates

por Becker-Pauly, Christoph, Barré, Olivier, Schilling, Oliver, auf dem Keller, Ulrich, Ohler, Anke, Broder, Claudia, Schütte, André, Kappelhoff, Reinhild, Stöcker, Walter, Overall, Christopher M.
Publicado 2011