Extracellular ATP and the P2X(7 )receptor in astrocyte-mediated motor neuron death: implications for amyotrophic lateral sclerosis

por Gandelman, Mandi, Peluffo, Hugo, Beckman, Joseph S, Cassina, Patricia, Barbeito, Luis
Publicado 2010

Imidazole catalyzes chlorination by unreactive primary chloramines

por Roemeling, Margo D., Williams, Jared, Beckman, Joseph S., Hurst, James K.
Publicado 2015

Nanobody assemblies with fully flexible topology enabled by genetically encoded tetrazine amino acids

por Van Fossen, Elise M., Bednar, Riley M., Jana, Subhashis, Franklin, Rachel, Beckman, Joseph, Karplus, P. Andrew, Mehl, Ryan A.
Publicado 2022

Enhanced Top-Down Protein Characterization with Electron Capture Dissociation and Cyclic Ion Mobility Spectrometry

por Shaw, Jared B., Cooper-Shepherd, Dale A., Hewitt, Darren, Wildgoose, Jason L., Beckman, Joseph S., Langridge, James I., Voinov, Valery G.
Publicado 2022

Emergence of Microglia Bearing Senescence Markers During Paralysis Progression in a Rat Model of Inherited ALS

por Trias, Emiliano, Beilby, Pamela R., Kovacs, Mariángeles, Ibarburu, Sofía, Varela, Valentina, Barreto-Núñez, Romina, Bradford, Samuel C., Beckman, Joseph S., Barbeito, Luis
Publicado 2019

Exploring ECD on a Benchtop Q Exactive Orbitrap Mass Spectrometer

por Fort, Kyle L., Cramer, Christian N., Voinov, Valery G., Vasil’ev, Yury V., Lopez, Nathan I., Beckman, Joseph S., Heck, Albert J. R.
Publicado 2017

CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS

por Kovacs, Mariángeles, Trias, Emiliano, Varela, Valentina, Ibarburu, Sofia, Beckman, Joseph S., Moura, Ivan C., Hermine, Olivier, King, Peter H., Si, Ying, Kwon, Yuri, Barbeito, Luis
Publicado 2019

PermaPhos(Ser): autonomous synthesis of functional, permanently phosphorylated proteins

por Zhu, Phillip, Franklin, Rachel, Vogel, Amber, Stanisheuski, Stanislau, Reardon, Patrick, Sluchanko, Nikolai N., Beckman, Joseph S., Karplus, P. Andrew, Mehl, Ryan A., Cooley, Richard B.
Publicado 2021

Phenotypic transition of microglia into astrocyte-like cells associated with disease onset in a model of inherited ALS

por Trias, Emiliano, Díaz-Amarilla, Pablo, Olivera-Bravo, Silvia, Isasi, Eugenia, Drechsel, Derek A., Lopez, Nathan, Bradford, C. Samuel, Ireton, Kyle E., Beckman, Joseph S., Barbeito, Luis
Publicado 2013

Autonomous Synthesis of Functional, Permanently Phosphorylated Proteins for Defining the Interactome of Monomeric 14-3-3ζ

por Zhu, Phillip, Stanisheuski, Stanislau, Franklin, Rachel, Vogel, Amber, Vesely, Cat Hoang, Reardon, Patrick, Sluchanko, Nikolai N., Beckman, Joseph S., Karplus, P. Andrew, Mehl, Ryan A., Cooley, Richard B.
Publicado 2023

Comparative Structural Analysis of 20S Proteasome Ortholog Protein Complexes by Native Mass Spectrometry

por Vimer, Shay, Ben-Nissan, Gili, Morgenstern, David, Kumar-Deshmukh, Fanindra, Polkinghorn, Caley, Quintyn, Royston S., Vasil’ev, Yury V., Beckman, Joseph S., Elad, Nadav, Wysocki, Vicki H., Sharon, Michal
Publicado 2020

Improved Protein and PTM Characterization with a Practical Electron-Based Fragmentation on Q-TOF Instruments

por Beckman, Joseph S., Voinov, Valery G., Hare, Michael, Sturgeon, Derrill, Vasil’ev, Yury, Oppenheimer, Diana, Shaw, Jared B., Wu, Shuai, Glaskin, Rebecca, Klein, Christian, Schwarzer, Cody, Stafford, George
Publicado 2021

Cu(II)(atsm) improves the neurological phenotype and survival of SOD1(G93A) mice and selectively increases enzymatically active SOD1 in the spinal cord

por Hilton, James B., Mercer, Stephen W., Lim, Nastasia K. H., Faux, Noel G., Buncic, Gojko, Beckman, Joseph S., Roberts, Blaine R., Donnelly, Paul S., White, Anthony R., Crouch, Peter J.
Publicado 2017

CuATSM effectively ameliorates ALS patient astrocyte‐mediated motor neuron toxicity in human in vitro models of amyotrophic lateral sclerosis

por Dennys, Cassandra N., Roussel, Florence, Rodrigo, Rochelle, Zhang, Xiaojin, Sierra Delgado, Andrea, Hartlaub, Annalisa, Saelim‐Ector, Asya, Ray, Will, Heintzman, Sarah, Fox, Ashley, Kolb, Stephen J., Beckman, Joseph, Franco, Maria Clara, Meyer, Kathrin
Publicado 2022

Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis

por Trias, Emiliano, Ibarburu, Sofía, Barreto-Núñez, Romina, Babdor, Joël, Maciel, Thiago T., Guillo, Matthias, Gros, Laurent, Dubreuil, Patrice, Díaz-Amarilla, Pablo, Cassina, Patricia, Martínez-Palma, Laura, Moura, Ivan C., Beckman, Joseph S., Hermine, Olivier, Barbeito, Luis
Publicado 2016