Reconciling evidence-based medicine and precision medicine in the era of big data: challenges and opportunities

por Beckmann, Jacques S., Lew, Daniel
Publicado 2016

The Growing Importance of CNVs: New Insights for Detection and Clinical Interpretation

por Valsesia, Armand, Macé, Aurélien, Jacquemont, Sébastien, Beckmann, Jacques S., Kutalik, Zoltán
Publicado 2013

Trick or treat: The effect of placebo on the power of pharmacogenetic association studies

por Singer, Clara, Grossman, Iris, Avidan, Nili, Beckmann, Jacques S, Pe'er, Itsik
Publicado 2005

RNAseq analysis of heart tissue from mice treated with atenolol and isoproterenol reveals a reciprocal transcriptional response

por Prunotto, Andrea, Stevenson, Brian J., Berthonneche, Corinne, Schüpfer, Fanny, Beckmann, Jacques S., Maurer, Fabienne, Bergmann, Sven
Publicado 2016

Great future or greedy venture: Precision medicine needs philosophy

por Jiao, Fei, Guo, Ruoyu, Beckmann, Jacques S., Yan, Zhonghai, Yang, Yun, Hu, Jinxia, Wang, Xin, Xie, Shuyang
Publicado 2021

In Vitro Whole-Genome Analysis Identifies a Susceptibility Locus for HIV-1

por Loeuillet, Corinne, Deutsch, Samuel, Ciuffi, Angela, Robyr, Daniel, Taffé, Patrick, Muñoz, Miguel, Beckmann, Jacques S, Antonarakis, Stylianos E, Telenti, Amalio
Publicado 2008

Genomic determinants of the efficiency of internal ribosomal entry sites of viral and cellular origin

por Kazadi, Kayole, Loeuillet, Corinne, Deutsch, Samuel, Ciuffi, Angela, Muñoz, Miguel, Beckmann, Jacques S., Moradpour, Darius, Antonarakis, Stylianos E., Telenti, Amalio
Publicado 2008

Cardiovascular Response to Beta-Adrenergic Blockade or Activation in 23 Inbred Mouse Strains

por Berthonneche, Corinne, Peter, Bastian, Schüpfer, Fanny, Hayoz, Pamela, Kutalik, Zoltán, Abriel, Hugues, Pedrazzini, Thierry, Beckmann, Jacques S., Bergmann, Sven, Maurer, Fabienne
Publicado 2009

High-level transgene expression by homologous recombination-mediated gene transfer

por Grandjean, Mélanie, Girod, Pierre-Alain, Calabrese, David, Kostyrko, Kaja, Wicht, Marianne, Yerly, Florence, Mazza, Christian, Beckmann, Jacques S., Martinet, Danielle, Mermod, Nicolas
Publicado 2011

Mapping Genetic Variants Associated with Beta-Adrenergic Responses in Inbred Mice

por Hersch, Micha, Peter, Bastian, Kang, Hyun Min, Schüpfer, Fanny, Abriel, Hugues, Pedrazzini, Thierry, Eskin, Eleazar, Beckmann, Jacques S., Bergmann, Sven, Maurer, Fabienne
Publicado 2012

Correction: Mapping Genetic Variants Associated with Beta-Adrenergic Responses in Inbred Mice

por Hersch, Micha, Peter, Bastian, Kang, Hyun Min, Schüpfer, Fanny, Abriel, Hugues, Pedrazzini, Thierry, Eskin, Eleazar, Beckmann, Jacques S., Bergmann, Sven, Maurer, Fabienne
Publicado 2014

Global Transcriptional Programs in Peripheral Nerve Endoneurium and DRG Are Resistant to the Onset of Type 1 Diabetic Neuropathy in Ins2(Akita/+) Mice

por de Preux Charles, Anne-Sophie, Verdier, Valérie, Zenker, Jennifer, Peter, Bastian, Médard, Jean-Jacques, Kuntzer, Thierry, Beckmann, Jacques S., Bergmann, Sven, Chrast, Roman
Publicado 2010

Identification and validation of copy number variants using SNP genotyping arrays from a large clinical cohort

por Valsesia, Armand, Stevenson, Brian J, Waterworth, Dawn, Mooser, Vincent, Vollenweider, Peter, Waeber, Gérard, Jongeneel, C Victor, Beckmann, Jacques S, Kutalik, Zoltán, Bergmann, Sven
Publicado 2012

Carriers of the fragile X mental retardation 1 (FMR1) premutation allele present with increased levels of cytokine IL-10

por Marek, Diana, Papin, Stephanie, Ellefsen, Kim, Niederhauser, Julien, Isidor, Nathalie, Ransijn, Adriana, Poupon, Lucienne, Spertini, Francois, Pantaleo, Giuseppe, Bergmann, Sven, Beckmann, Jacques S, Jacquemont, Sebastien, Tanackovic, Goranka
Publicado 2012

Loss of Calpain 3 Proteolytic Activity Leads to Muscular Dystrophy and to Apoptosis-Associated Iκbα/Nuclear Factor κb Pathway Perturbation in Mice

por Richard, Isabelle, Roudaut, Carinne, Marchand, Sylvie, Baghdiguian, Stephen, Herasse, Muriel, Stockholm, Daniel, Ono, Yasuko, Suel, Laurence, Bourg, Nathalie, Sorimachi, Hiroyuki, Lefranc, Gérard, Fardeau, Michel, Sébille, Alain, Beckmann, Jacques S.
Publicado 2000

Association of ABCB1 genetic variants with renal function in Africans and in Caucasians

por Bochud, Murielle, Eap, Chin B, Maillard, Marc, Johnson, Toby, Vollenweider, Peter, Bovet, Pascal, Elston, Robert C, Bergmann, Sven, Beckmann, Jacques S, Waterworth, Dawn M, Mooser, Vincent, Gabriel, Anne, Burnier, Michel
Publicado 2008

KCTD13 is a major driver of mirrored neuroanatomical phenotypes associated with the 16p11.2 CNV

por Golzio, Christelle, Willer, Jason, Talkowski, Michael E, Oh, Edwin C, Taniguchi, Yu, Jacquemont, Sébastien, Reymond, Alexandre, Sun, Mei, Sawa, Akira, Gusella, James F, Kamiya, Atsushi, Beckmann, Jacques S, Katsanis, Nicholas
Publicado 2012

GWAS of human bitter taste perception identifies new loci and reveals additional complexity of bitter taste genetics

por Ledda, Mirko, Kutalik, Zoltán, Souza Destito, Maria C., Souza, Milena M., Cirillo, Cintia A., Zamboni, Amabilene, Martin, Nathalie, Morya, Edgard, Sameshima, Koichi, Beckmann, Jacques S., le Coutre, Johannes, Bergmann, Sven, Genick, Ulrich K.
Publicado 2014

A single epidermal stem cell strategy for safe ex vivo gene therapy

por Droz-Georget Lathion, Stéphanie, Rochat, Ariane, Knott, Graham, Recchia, Alessandra, Martinet, Danielle, Benmohammed, Sara, Grasset, Nicolas, Zaffalon, Andrea, Besuchet Schmutz, Nathalie, Savioz-Dayer, Emmanuelle, Beckmann, Jacques Samuel, Rougemont, Jacques, Mavilio, Fulvio, Barrandon, Yann
Publicado 2015

Network-Guided Analysis of Genes with Altered Somatic Copy Number and Gene Expression Reveals Pathways Commonly Perturbed in Metastatic Melanoma

por Valsesia, Armand, Rimoldi, Donata, Martinet, Danielle, Ibberson, Mark, Benaglio, Paola, Quadroni, Manfredo, Waridel, Patrice, Gaillard, Muriel, Pidoux, Mireille, Rapin, Blandine, Rivolta, Carlo, Xenarios, Ioannis, Simpson, Andrew J. G., Antonarakis, Stylianos E., Beckmann, Jacques S., Jongeneel, C. Victor, Iseli, Christian, Stevenson, Brian J.
Publicado 2011