Detecting epigenetic motifs in low coverage and metagenomics settings

por Beckmann, Noam D, Karri, Sashank, Fang, Gang, Bashir, Ali
Publicado 2014

A new molecular signature method for prediction of driver cancer pathways from transcriptional data

por Rykunov, Dmitry, Beckmann, Noam D., Li, Hui, Uzilov, Andrew, Schadt, Eric E., Reva, Boris
Publicado 2016

Dual-Specificity Protein Phosphatase 4 (DUSP4) Overexpression Improves Learning Behavior Selectively in Female 5xFAD Mice, and Reduces β-Amyloid Load in Males and Females

por Pan, Allen L., Audrain, Mickael, Sakakibara, Emmy, Joshi, Rajeev, Zhu, Xiaodong, Wang, Qian, Wang, Minghui, Beckmann, Noam D., Schadt, Eric E., Gandy, Sam, Zhang, Bin, Ehrlich, Michelle E., Salton, Stephen R.
Publicado 2022

Predictive network modeling in human induced pluripotent stem cells identifies key driver genes for insulin responsiveness

por Carcamo-Orive, Ivan, Henrion, Marc Y. R., Zhu, Kuixi, Beckmann, Noam D., Cundiff, Paige, Moein, Sara, Zhang, Zenan, Alamprese, Melissa, D’Souza, Sunita L., Wabitsch, Martin, Schadt, Eric E., Quertermous, Thomas, Knowles, Joshua W., Chang, Rui
Publicado 2020

Late-onset megaconial myopathy in mice lacking group I Paks

por Joseph, Giselle A., Hung, Margaret, Goel, Aviva J., Hong, Mingi, Rieder, Marysia-Kolbe, Beckmann, Noam D., Serasinghe, Madhavika N., Chipuk, Jerry E., Devarakonda, Parvathi M., Goldhamer, David J., Aldana-Hernandez, Paulina, Curtis, Jonathan, Jacobs, René L., Krauss, Robert S.
Publicado 2019

Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks

por Glicksberg, Benjamin S., Li, Li, Badgeley, Marcus A., Shameer, Khader, Kosoy, Roman, Beckmann, Noam D., Pho, Nam, Hakenberg, Jörg, Ma, Meng, Ayers, Kristin L., Hoffman, Gabriel E., Dan Li, Shuyu, Schadt, Eric E., Patel, Chirag J., Chen, Rong, Dudley, Joel T.
Publicado 2016

A Molecular network approach reveals shared cellular and molecular signatures between chronic fatigue syndrome and other fatiguing illnesses

por Comella, Phillip H., Gonzalez-Kozlova, Edgar, Kosoy, Roman, Charney, Alexander W., Peradejordi, Irene Font, Chandrasekar, Shreya, Tyler, Scott R., Wang, Wenhui, Losic, Bojan, Zhu, Jun, Hoffman, Gabriel E., Kim-Schulze, Seunghee, Qi, Jingjing, Patel, Manishkumar, Kasarskis, Andrew, Suarez-Farinas, Mayte, Gümüş, Zeynep H., Argmann, Carmen, Merad, Miriam, Becker, Christian, Beckmann, Noam D., Schadt, Eric E.
Publicado 2021

An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease

por Cohain, Ariella T., Barrington, William T., Jordan, Daniel M., Beckmann, Noam D., Argmann, Carmen A., Houten, Sander M., Charney, Alexander W., Ermel, Raili, Sukhavasi, Katyayani, Franzen, Oscar, Koplev, Simon, Whatling, Carl, Belbin, Gillian M., Yang, Jialiang, Hao, Ke, Kenny, Eimear E., Tu, Zhidong, Zhu, Jun, Gan, Li-Ming, Do, Ron, Giannarelli, Chiara, Kovacic, Jason C., Ruusalepp, Arno, Lusis, Aldons J., Bjorkegren, Johan L. M., Schadt, Eric E.
Publicado 2021

The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease

por Wang, Minghui, Beckmann, Noam D., Roussos, Panos, Wang, Erming, Zhou, Xianxiao, Wang, Qian, Ming, Chen, Neff, Ryan, Ma, Weiping, Fullard, John F., Hauberg, Mads E., Bendl, Jaroslav, Peters, Mette A., Logsdon, Ben, Wang, Pei, Mahajan, Milind, Mangravite, Lara M., Dammer, Eric B., Duong, Duc M., Lah, James J., Seyfried, Nicholas T., Levey, Allan I., Buxbaum, Joseph D., Ehrlich, Michelle, Gandy, Sam, Katsel, Pavel, Haroutunian, Vahram, Schadt, Eric, Zhang, Bin
Publicado 2018

IL10RB as a key regulator of COVID-19 host susceptibility and severity

por Voloudakis, Georgios, Hoffman, Gabriel, Venkatesh, Sanan, Lee, Kyung Min, Dobrindt, Kristina, Vicari, James M., Zhang, Wen, Beckmann, Noam D., Jiang, Shan, Hoagland, Daisy, Bian, Jiantao, Gao, Lina, Corvelo, André, Cho, Kelly, Lee, Jennifer S., Iyengar, Sudha K., Luoh, Shiuh-Wen, Akbarian, Schahram, Striker, Robert, Assimes, Themistocles L., Schadt, Eric E., Merad, Miriam, tenOever, Benjamin R., Charney, Alexander W., Brennand, Kristen J., Lynch, Julie A., Fullard, John F., Roussos, Panos
Publicado 2021

A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility

por Voloudakis, Georgios, Vicari, James M., Venkatesh, Sanan, Hoffman, Gabriel E., Dobrindt, Kristina, Zhang, Wen, Beckmann, Noam D., Higgins, Christina A., Argyriou, Stathis, Jiang, Shan, Hoagland, Daisy, Gao, Lina, Corvelo, André, Cho, Kelly, Lee, Kyung Min, Bian, Jiantao, Lee, Jennifer S., Iyengar, Sudha K., Luoh, Shiuh-Wen, Akbarian, Schahram, Striker, Robert, Assimes, Themistocles L., Schadt, Eric E., Lynch, Julie A., Merad, Miriam, tenOever, Benjamin R., Charney, Alexander W., Brennand, Kristen J., Fullard, John F., Roussos, Panos
Publicado 2022

Genome-Wide Meta-Analysis for Serum Calcium Identifies Significantly Associated SNPs near the Calcium-Sensing Receptor (CASR) Gene

por Kapur, Karen, Johnson, Toby, Beckmann, Noam D., Sehmi, Joban, Tanaka, Toshiko, Kutalik, Zoltán, Styrkarsdottir, Unnur, Zhang, Weihua, Marek, Diana, Gudbjartsson, Daniel F., Milaneschi, Yuri, Holm, Hilma, DiIorio, Angelo, Waterworth, Dawn, Li, Yun, Singleton, Andrew B., Bjornsdottir, Unnur S., Sigurdsson, Gunnar, Hernandez, Dena G., DeSilva, Ranil, Elliott, Paul, Eyjolfsson, Gudmundur I., Guralnik, Jack M., Scott, James, Thorsteinsdottir, Unnur, Bandinelli, Stefania, Chambers, John, Stefansson, Kari, Waeber, Gérard, Ferrucci, Luigi, Kooner, Jaspal S., Mooser, Vincent, Vollenweider, Peter, Beckmann, Jacques S., Bochud, Murielle, Bergmann, Sven
Publicado 2010

Acute COVID-19 gene-expression profiles show multiple etiologies of long-term sequelae

por Thompson, Ryan C., Simons, Nicole W., Wilkins, Lillian, Cheng, Esther, Del Valle, Diane Marie, Hoffman, Gabriel E., Fennessy, Brian, Mouskas, Konstantinos, Francoeur, Nancy J., Johnson, Jessica S., Lepow, Lauren, Le Berichel, Jessica, Chang, Christie, Beckmann, Aviva G., Wang, Ying-chih, Nie, Kai, Zaki, Nicholas, Tuballes, Kevin, Barcessat, Vanessa, Cedillo, Mario A., Huckins, Laura, Roussos, Panagiotis, Marron, Thomas U., Glicksberg, Benjamin S., Nadkarni, Girish, Gonzalez-Kozlova, Edgar, Kim-Schulze, Seunghee, Sebra, Robert, Merad, Miriam, Gnjatic, Sacha, Schadt, Eric E., Charney, Alexander W., Beckmann, Noam D.
Publicado 2021

A shift in lung macrophage composition is associated with COVID-19 severity and recovery

por Chen, Steven T., Park, Matthew D., Del Valle, Diane Marie, Buckup, Mark, Tabachnikova, Alexandra, Thompson, Ryan C., Simons, Nicole W., Mouskas, Konstantinos, Lee, Brian, Geanon, Daniel, D’Souza, Darwin, Dawson, Travis, Marvin, Robert, Nie, Kai, Zhao, Zhen, LeBerichel, Jessica, Chang, Christie, Jamal, Hajra, Akturk, Guray, Chaddha, Udit, Mathews, Kusum, Acquah, Samuel, Brown, Stacey-Ann, Reiss, Michelle, Harkin, Timothy, Feldmann, Marc, Powell, Charles A., Hook, Jaime L., Kim-Schulze, Seunghee, Rahman, Adeeb H., Brown, Brian D., Beckmann, Noam D., Gnjatic, Sacha, Kenigsberg, Ephraim, Charney, Alexander W., Merad, Miriam
Publicado 2022

A 600 kb deletion syndrome at 16p11.2 leads to energy imbalance and neuropsychiatric disorders

por Zufferey, Flore, Sherr, Elliott H, Beckmann, Noam D, Hanson, Ellen, Maillard, Anne M, Hippolyte, Loyse, Macé, Aurélien, Ferrari, Carina, Kutalik, Zoltán, Andrieux, Joris, Aylward, Elizabeth, Barker, Mandy, Bernier, Raphael, Bouquillon, Sonia, Conus, Philippe, Delobel, Bruno, Faucett, W Andrew, Goin-Kochel, Robin P, Grant, Ellen, Harewood, Louise, Hunter, Jill V, Lebon, Sébastien, Ledbetter, David H, Martin, Christa Lese, Männik, Katrin, Martinet, Danielle, Mukherjee, Pratik, Ramocki, Melissa B, Spence, Sarah J, Steinman, Kyle J, Tjernagel, Jennifer, Spiro, John E, Reymond, Alexandre, Beckmann, Jacques S, Chung, Wendy K, Jacquemont, Sébastien
Publicado 2012

Multiscale causal networks identify VGF as a key regulator of Alzheimer’s disease

por Beckmann, Noam D., Lin, Wei-Jye, Wang, Minghui, Cohain, Ariella T., Charney, Alexander W., Wang, Pei, Ma, Weiping, Wang, Ying-Chih, Jiang, Cheng, Audrain, Mickael, Comella, Phillip H., Fakira, Amanda K., Hariharan, Siddharth P., Belbin, Gillian M., Girdhar, Kiran, Levey, Allan I., Seyfried, Nicholas T., Dammer, Eric B., Duong, Duc, Lah, James J., Haure-Mirande, Jean-Vianney, Shackleton, Ben, Fanutza, Tomas, Blitzer, Robert, Kenny, Eimear, Zhu, Jun, Haroutunian, Vahram, Katsel, Pavel, Gandy, Sam, Tu, Zhidong, Ehrlich, Michelle E., Zhang, Bin, Salton, Stephen R., Schadt, Eric E.
Publicado 2020

Shift of lung macrophage composition is associated with COVID-19 disease severity and recovery

por Chen, Steven T., Park, Matthew D., Del Valle, Diane Marie, Buckup, Mark, Tabachnikova, Alexandra, Simons, Nicole W., Mouskas, Konstantinos, Lee, Brian, Geanon, Daniel, D’Souza, Darwin, Dawson, Travis, Marvin, Robert, Nie, Kai, Thompson, Ryan C., Zhao, Zhen, LeBerichel, Jessica, Chang, Christie, Jamal, Hajra, Chaddha, Udit, Mathews, Kusum, Acquah, Samuel, Brown, Stacey-Ann, Reiss, Michelle, Harkin, Timothy, Feldmann, Marc, Powell, Charles A., Hook, Jaime L., Kim-Schulze, Seunghee, Rahman, Adeeb H., Brown, Brian D., Beckmann, Noam D., Gnjatic, Sacha, Kenigsberg, Ephraim, Charney, Alexander W., Merad, Miriam
Publicado 2022

Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae

por Thompson, Ryan C., Simons, Nicole W., Wilkins, Lillian, Cheng, Esther, Del Valle, Diane Marie, Hoffman, Gabriel E., Cervia, Carlo, Fennessy, Brian, Mouskas, Konstantinos, Francoeur, Nancy J., Johnson, Jessica S., Lepow, Lauren, Le Berichel, Jessica, Chang, Christie, Beckmann, Aviva G., Wang, Ying-chih, Nie, Kai, Zaki, Nicholas, Tuballes, Kevin, Barcessat, Vanessa, Cedillo, Mario A., Yuan, Dan, Huckins, Laura, Roussos, Panos, Marron, Thomas U., Glicksberg, Benjamin S., Nadkarni, Girish, Heath, James R., Gonzalez-Kozlova, Edgar, Boyman, Onur, Kim-Schulze, Seunghee, Sebra, Robert, Merad, Miriam, Gnjatic, Sacha, Schadt, Eric E., Charney, Alexander W., Beckmann, Noam D.
Publicado 2022

The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target

por Petyuk, Vladislav A, Chang, Rui, Ramirez-Restrepo, Manuel, Beckmann, Noam D, Henrion, Marc Y R, Piehowski, Paul D, Zhu, Kuixi, Wang, Sven, Clarke, Jennifer, Huentelman, Matthew J, Xie, Fang, Andreev, Victor, Engel, Anzhelika, Guettoche, Toumy, Navarro, Loida, De Jager, Philip, Schneider, Julie A, Morris, Christopher M, McKeith, Ian G, Perry, Robert H, Lovestone, Simon, Woltjer, Randall L, Beach, Thomas G, Sue, Lucia I, Serrano, Geidy E, Lieberman, Andrew P, Albin, Roger L, Ferrer, Isidre, Mash, Deborah C, Hulette, Christine M, Ervin, John F, Reiman, Eric M, Hardy, John A, Bennett, David A, Schadt, Eric, Smith, Richard D, Myers, Amanda J
Publicado 2018

Machine Learning to Predict Mortality and Critical Events in a Cohort of Patients With COVID-19 in New York City: Model Development and Validation

por Vaid, Akhil, Somani, Sulaiman, Russak, Adam J, De Freitas, Jessica K, Chaudhry, Fayzan F, Paranjpe, Ishan, Johnson, Kipp W, Lee, Samuel J, Miotto, Riccardo, Richter, Felix, Zhao, Shan, Beckmann, Noam D, Naik, Nidhi, Kia, Arash, Timsina, Prem, Lala, Anuradha, Paranjpe, Manish, Golden, Eddye, Danieletto, Matteo, Singh, Manbir, Meyer, Dara, O'Reilly, Paul F, Huckins, Laura, Kovatch, Patricia, Finkelstein, Joseph, Freeman, Robert M., Argulian, Edgar, Kasarskis, Andrew, Percha, Bethany, Aberg, Judith A, Bagiella, Emilia, Horowitz, Carol R, Murphy, Barbara, Nestler, Eric J, Schadt, Eric E, Cho, Judy H, Cordon-Cardo, Carlos, Fuster, Valentin, Charney, Dennis S, Reich, David L, Bottinger, Erwin P, Levin, Matthew A, Narula, Jagat, Fayad, Zahi A, Just, Allan C, Charney, Alexander W, Nadkarni, Girish N, Glicksberg, Benjamin S
Publicado 2020