Computational Study of Protein-Ligand Unbinding for Enzyme Engineering

por Marques, Sérgio M., Bednar, David, Damborsky, Jiri
Publicado 2019

Structural Biology and Protein Engineering of Thrombolytics

por Mican, Jan, Toul, Martin, Bednar, David, Damborsky, Jiri
Publicado 2019

HotSpot Wizard 3.0: web server for automated design of mutations and smart libraries based on sequence input information

por Sumbalova, Lenka, Stourac, Jan, Martinek, Tomas, Bednar, David, Damborsky, Jiri
Publicado 2018

Atypical homodimerization revealed by the structure of the (S)-enantioselective haloalkane dehalogenase DmmarA from Mycobacterium marinum

por Snajdarova, Karolina, Marques, Sérgio M., Damborsky, Jiri, Bednar, David, Marek, Martin
Publicado 2023

Structures of hyperstable ancestral haloalkane dehalogenases show restricted conformational dynamics

por Babkova, Petra, Dunajova, Zuzana, Chaloupkova, Radka, Damborsky, Jiri, Bednar, David, Marek, Martin
Publicado 2020

Substrate inhibition by the blockage of product release and its control by tunnel engineering

por Kokkonen, Piia, Beier, Andy, Mazurenko, Stanislav, Damborsky, Jiri, Bednar, David, Prokop, Zbynek
Publicado 2021

Fast Screening of Inhibitor Binding/Unbinding Using Novel Software Tool CaverDock

por Pinto, Gaspar P., Vavra, Ondrej, Filipovic, Jiri, Stourac, Jan, Bednar, David, Damborsky, Jiri
Publicado 2019

Screening of Natural Compounds as P-Glycoprotein Inhibitors against Multidrug Resistance

por Marques, Sérgio M., Šupolíková, Lucie, Molčanová, Lenka, Šmejkal, Karel, Bednar, David, Slaninová, Iva
Publicado 2021

FireProt 2.0: web-based platform for the fully automated design of thermostable proteins

por Musil, Milos, Jezik, Andrej, Horackova, Jana, Borko, Simeon, Kabourek, Petr, Damborsky, Jiri, Bednar, David
Publicado 2023

CalFitter: a web server for analysis of protein thermal denaturation data

por Mazurenko, Stanislav, Stourac, Jan, Kunka, Antonin, Nedeljković, Sava, Bednar, David, Prokop, Zbynek, Damborsky, Jiri
Publicado 2018

FireProt(DB): database of manually curated protein stability data

por Stourac, Jan, Dubrava, Juraj, Musil, Milos, Horackova, Jana, Damborsky, Jiri, Mazurenko, Stanislav, Bednar, David
Publicado 2020

SoluProt: prediction of soluble protein expression in Escherichia coli

por Hon, Jiri, Marusiak, Martin, Martinek, Tomas, Kunka, Antonin, Zendulka, Jaroslav, Bednar, David, Damborsky, Jiri
Publicado 2021

Screening of world approved drugs against highly dynamical spike glycoprotein of SARS-CoV-2 using CaverDock and machine learning

por Pinto, Gaspar P., Vavra, Ondrej, Marques, Sergio M., Filipovic, Jiri, Bednar, David, Damborsky, Jiri
Publicado 2021

A Nonconventional Archaeal Fluorinase Identified by In Silico Mining for Enhanced Fluorine Biocatalysis

por Pardo, Isabel, Bednar, David, Calero, Patricia, Volke, Daniel C., Damborský, Jiří, Nikel, Pablo I.
Publicado 2022

SoluProtMut(DB): A manually curated database of protein solubility changes upon mutations

por Velecký, Jan, Hamsikova, Marie, Stourac, Jan, Musil, Milos, Damborsky, Jiri, Bednar, David, Mazurenko, Stanislav
Publicado 2022

Decoding the intricate network of molecular interactions of a hyperstable engineered biocatalyst

por Markova, Klara, Chmelova, Klaudia, Marques, Sérgio M., Carpentier, Philippe, Bednar, David, Damborsky, Jiri, Marek, Martin
Publicado 2020

FireProt(ASR): A Web Server for Fully Automated Ancestral Sequence Reconstruction

por Musil, Milos, Khan, Rayyan Tariq, Beier, Andy, Stourac, Jan, Konegger, Hannes, Damborsky, Jiri, Bednar, David
Publicado 2020

pyCaverDock: Python implementation of the popular tool for analysis of ligand transport with advanced caching and batch calculation support

por Vavra, Ondrej, Beranek, Jakub, Stourac, Jan, Surkovsky, Martin, Filipovic, Jiri, Damborsky, Jiri, Martinovic, Jan, Bednar, David
Publicado 2023

Caver Web 1.0: identification of tunnels and channels in proteins and analysis of ligand transport

por Stourac, Jan, Vavra, Ondrej, Kokkonen, Piia, Filipovic, Jiri, Pinto, Gaspar, Brezovsky, Jan, Damborsky, Jiri, Bednar, David
Publicado 2019

EnzymeMiner: automated mining of soluble enzymes with diverse structures, catalytic properties and stabilities

por Hon, Jiri, Borko, Simeon, Stourac, Jan, Prokop, Zbynek, Zendulka, Jaroslav, Bednar, David, Martinek, Tomas, Damborsky, Jiri
Publicado 2020