Inhibition of serum- and glucocorticoid-induced kinase 1 ameliorates hydrocephalus in preclinical models

por Hochstetler, Alexandra, Smith, Hillary, Reed, Makenna, Hulme, Louise, Territo, Paul, Bedwell, Amanda, Persohn, Scott, Perrotti, Nicola, D’Antona, Lucia, Musumeci, Francesca, Schenone, Silvia, Blazer-Yost, Bonnie L.
Publicado 2023

Cortical cerebrovascular and metabolic perturbations in the 5xFAD mouse model of Alzheimer’s disease

por Jullienne, Amandine, Szu, Jenny I., Quan, Ryan, Trinh, Michelle V., Norouzi, Tannoz, Noarbe, Brenda P., Bedwell, Amanda A., Eldridge, Kierra, Persohn, Scott C., Territo, Paul R., Obenaus, Andre
Publicado 2023

Plcg2(M28L) Interacts With High Fat/High Sugar Diet to Accelerate Alzheimer’s Disease-Relevant Phenotypes in Mice

por Oblak, Adrian L., Kotredes, Kevin P., Pandey, Ravi S., Reagan, Alaina M., Ingraham, Cynthia, Perkins, Bridget, Lloyd, Christopher, Baker, Deborah, Lin, Peter B., Soni, Disha M., Tsai, Andy P., Persohn, Scott A., Bedwell, Amanda A., Eldridge, Kierra, Speedy, Rachael, Meyer, Jill A., Peters, Johnathan S., Figueiredo, Lucas L., Sasner, Michael, Territo, Paul R., Sukoff Rizzo, Stacey J., Carter, Gregory W., Lamb, Bruce T., Howell, Gareth R.
Publicado 2022

Prophylactic evaluation of verubecestat on disease‐ and symptom‐modifying effects in 5XFAD mice

por Oblak, Adrian L., Cope, Zackary A., Quinney, Sara K., Pandey, Ravi S., Biesdorf, Carla, Masters, Andi R., Onos, Kristen D., Haynes, Leslie, Keezer, Kelly J., Meyer, Jill A., Peters, Jonathan S., Persohn, Scott A., Bedwell, Amanda A., Eldridge, Kierra, Speedy, Rachael, Little, Gabriela, Williams, Sean‐Paul, Noarbe, Brenda, Obenaus, Andre, Sasner, Michael, Howell, Gareth R., Carter, Gregory W., Williams, Harriet, Lamb, Bruce T., Territo, Paul R., Sukoff Rizzo, Stacey J.
Publicado 2022

Pharmacokinetic, pharmacodynamic, and transcriptomic analysis of chronic levetiracetam treatment in 5XFAD mice: A MODEL‐AD preclinical testing core study

por Onos, Kristen D., Quinney, Sara K., Jones, David R., Masters, Andrea R., Pandey, Ravi, Keezer, Kelly J., Biesdorf, Carla, Metzger, Ingrid F., Meyers, Jill A., Peters, Johnathon, Persohn, Scott C., McCarthy, Brian P., Bedwell, Amanda A., Figueiredo, Lucas L., Cope, Zackary A., Sasner, Michael, Howell, Gareth R., Williams, Harriet M., Oblak, Adrian L., Lamb, Bruce T., Carter, Gregory W., Rizzo, Stacey J. Sukoff, Territo, Paul R.
Publicado 2022